Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0752347 (Dementia with Lewy bodies)
 1,653 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
KIAA1024L 14.2
calsyntenin 1 12.2
breast carcinoma amplified sequence 1 11.9
dipeptidyl aminopeptidase-like protein 6 11.4
SNCB 11.3
Visinin-like protein 1 11.2
RUFY3 11.1
NUB1 10.8
MYH13 10.8
eukaryotic translation elongation factor 1 alpha 10.6
SP18 10.6
Alpha-mannosidase 10.6
alpha-synuclein 10.6
TPPP/p25 10.4
PRPH 10.3
PARK8 10.2
beta-synuclein 10.2
SNCAIP 10.2
PARP-14 10.2
Lemur tyrosine kinase 2 10.1
HERC6 10.1
TPPP 10.1
KCNMB2 9.9
GBA1 9.9
alpha synuclein 9.9
CASS4 9.7
PARK11 9.6
PARK13 9.5
RAB39B 9.5
synuclein 9.5
ZCWPW1 9.5
GPR78 9.4
VPS13C 9.4
synphilin-1 9.4
LBD 9.3
SNCA 9.1
OLF 9.1
AMBRA1 9.1
gamma-synuclein 9.1
PARP9 9.0
EA6 9.0
PSMB4 8.9
Cholinesterase 8.9
TMEM106B 8.9
EIF4G1 8.9
colony stimulating factor receptor 8.9
Synphilin-1 8.9
ITIH4 8.8
MS4A6A 8.8
ASH1L 8.8
PRND 8.8
highly charged protein 8.7
Toll-like receptor 1 8.7
AKR7A2 8.7
Glucocerebrosidase 8.7
SORL1 8.6
BS4 8.6
ECE-2 8.6
CIT 8.6
LRRK2 8.5
SPRING 8.5
ubiquitin C-terminal hydrolase 8.4
MBP1 8.4
PSEN2 8.4
NACP 8.4
PSEN1 8.4
FTD 8.4
MYH8 8.4
DPP7 8.4
CHCHD2 8.4
MIC1 8.3
PTK2B 8.3
eIF3e 8.3
SAF-1 8.2
TDP-43 8.2
natural killer cell receptor 8.2
small acidic protein 8.2
DCTN1 8.2
neurosin 8.2
MSA 8.1
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Disease
Pallidonigral degeneration 14.2
pathological emotionality 14.2
Dementia with Lewy bodies 14.2
Pallidoluysian atrophy 13.2
Dementia in Parkinson's disease 11.8
Pseudodementia 11.6
PARK5 10.9
REM sleep behavior disorder 10.8
Bone lesion 10.8
Striatonigral degeneration 10.8
Secondary parkinsonism 10.8
PARK13 10.6
Parkinson's disease and parkinsonism 10.5
Sundowning 10.4
Progressive dementia 10.4
Pick's disease 10.3
PARK4 10.2
PARK3 10.1
Pure autonomic failure 10.0
PARK11 10.0
PARK8 9.9
Multiple system atrophy 9.9
Vascular dementia 9.8
progressive supranuclear palsy 9.7
CARASIL 9.7
BPSD 9.6
Cranial nerves 9.5
Cranial nerves 9.5
Corticobasal degeneration 9.5
behavior disorder 9.4
Brissaud 9.3
parasomnia 9.3
astereognosis 9.2
FTLD 9.1
Familial amyloidosis 9.0
PARK1 8.8
hallucinations 8.8
Kluver-Bucy syndrome 8.8
Primary Progressive Aphasia 8.7
Neurodegenerative Disorders 8.7
PDD 8.7
Frontotemporal dementia 8.7
parkinsonism 8.6
LBD 8.5
brain anoxia 8.5
Capgras syndrome 8.4
FTD-ALS 8.4
dysautonomia 8.4
dementia 8.3
Demented 8.2
primary lateral sclerosis 8.1
MSA 8.1
Meige syndrome 8.1
Pisa syndrome 8.1
extrapyramidal disorder 8.1
alcoholic dementia 8.0
Parkinson's disease 8.0
PSP 7.9
Hallervorden-Spatz disease 7.9
PARK2 7.8
autonomic disorder 7.8
Balint's syndrome 7.8
PARK7 7.8
CJD 7.7
Bielschowsky 7.7
Cotard's syndrome 7.7
PARK6 7.5
delusions 7.4
Creutzfeldt-Jakob disease 7.4
KRS 7.4
Hippocampal sclerosis 7.4
olivopontocerebellar atrophy 7.3
Alzheimer's disease 7.3
hallucinosis 7.3
ALS2 7.3
cognitive disorder 7.2
Charles Bonnet syndrome 7.2
apraxia 7.2
early disease onset 7.1
agnosia 7.1
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Symptom
Extrapyramidal rigidity 12.6
Retropulsion 11.5
visual hallucination 10.4
Postural tremor 9.1
Behavioral symptoms 8.9
Hemiballism 8.6
Rest tremor 8.5
Visual symptoms 8.4
Psychiatric symptoms 7.9
bradykinesia 7.6
asterixis 6.5
apathy 6.5
motor symptom 6.4
metamorphopsia 6.3
physical symptom 6.3
anosmia 6.2
auditory hallucination 6.2
athetosis 6.2
catatonia 6.1
tremor 6.1
myoclonus 6.0
memory loss 5.9
Poor sleep 5.7
dystonia 5.6
Involuntary Movement 5.6
blepharospasm 5.2
muscle rigidity 5.2
clumsiness 5.1
personality change 5.1
agitation 5.1
Gastrointestinal symptoms 5.0
Fluctuation 5.0
chorea 4.8
syncope 4.4
constipation 4.2
hypersomnia 4.2
eds 4.2
abnormal gait 4.1
cerebellar ataxia 4.0
dysuria 4.0
dysarthria 3.9
sleepiness 3.8
ataxia 3.6
ophthalmoplegia 3.5
sneezing 3.3
Depressive symptoms 3.3
leg pain 3.2
stridor 3.0
paraparesis 2.8
snoring 2.7
paresis 2.7
dizziness 2.6
spasticity 2.6
insomnia 2.4
numbness 1.9
thinning 1.8
cachexia 1.8
lethargy 1.8
weakness 1.6
anorexia 1.5
vertigo 1.4
spasm 1.4
nausea 1.3
respiratory distress 1.0
vomiting 0.9
fatigue 0.6
stigma 0.5
cough -0.3
dyspnea -0.5
headache -0.5
abdominal pain -0.7
seizures -1.1
pain -1.4
diarrhea -1.6
Drug
Exametazime 10.4
Gluconolactone 10.0
Azilect 9.9
Donepezil 8.3
Domin 7.8
Rotigotine 7.6
Aricept 7.5
Mazindol 7.4
Tianeptine 6.9
Pramipexole 6.6
Pramipexole 6.5
Parkin 6.4
Parkin 6.4
Escitalopram 6.3
Frontal 6.2
IPD 6.0
Modafinil 5.6
PPA 5.0
CFT 5.0
Xanthium 4.5
Paraffin 4.1
MDS 4.1
Vitamin B12 4.0
Vitamin B 3.9
Lovastatin 3.9
Phenytoin 3.9
ROC 3.6
Heme 3.6
Triclosan 3.6
CSF 3.4
Fluorescein 3.4
Portal 3.2
ETS 2.9
Vitamin E 2.6
HCH 2.5
Spectrum 2.3
vitamin E 2.1
citric acid 1.0
Leaf 0.8
ascorbate 0.7
lysine 0.4
lactose 0.2
ROS -0.0
caffeine -0.2
NADH -0.2
IL-2 -0.6
Monit -0.9
Enzyme
neurosin 9.2
phospholipid:diacylglycerol acyltransferase 8.4
glucocerebrosidase 8.2
DAP II 7.5
isopeptidase 7.1
cholinesterase 6.4
cathepsin H 5.7
DAT 5.7
acetylcholinesterase 5.6
prolyl endopeptidase 5.6
Thy1 5.6
proteinase K 5.2
endothelin-converting enzyme 4.9
tyrosine hydroxylase 4.9
mu-calpain 4.8
insulin-degrading enzyme 4.7
caspase-2 4.6
ubiquitin-protein ligase 4.6
caspase-2 4.6
GRK2 4.5
tryptophan hydroxylase 4.4
beta-secretase 4.4
choline acetyltransferase 4.4
MEKK1 4.4
mannanase 4.3
cathepsin D 4.2
GRK5 4.1
proteasome 4.1
enolase 4.0
heparinase 3.9
complex I 3.7
alpha-mannosidase 3.7
protein phosphatase 2A 3.7
PTA 3.5
monoamine oxidase 3.4
BAL 3.3
cathepsin B 3.2
tryptase 2.8
CYP3A4 2.6
CPT 2.6
GSK 2.5
CPT 2.5
pyruvate dehydrogenase 2.5
pyruvate dehydrogenase 2.5
hexosaminidase 2.4
CaMKII 2.3
gamma-glutamyl transpeptidase 2.1
CPT 2.1
IKK 2.0
CPR 1.9
pyruvate dehydrogenase 1.8
diaphorase 1.7
kallikrein 1.7
ornithine decarboxylase 1.6
PARP 1.5
phospholipase A2 1.4
NOS 1.4
caspase-9 1.4
calcineurin 1.2
mitogen-activated protein kinase 1.1
cytochrome oxidase 1.1
caspase-3 1.1
MEK 1.1
phospholipase C 1.1
glutathione reductase 1.0
ERK 1.0
superoxide dismutase 1.0
NADPH oxidase 0.9
chymotrypsin 0.8
glutathione peroxidase 0.8
catalase 0.8
NADPH oxidase 0.8
protein kinase 0.7
AMP-activated protein kinase 0.6
trypsin 0.5
beta-galactosidase 0.4
focal adhesion kinase 0.4
ACE 0.1
creatine kinase 0.0
protein kinase C -0.4
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Compound
Carbidopa-levodopa 11.2
ethyl methylcarbamate 10.8
Thioflavine S 9.8
Rivastigmine 9.3
Gluconolactone 9.3
Donepezil hydrochloride 9.2
hexadecanedioic acid 8.6
methyl carbamate 8.4
Tuberin 8.0
PSP 7.7
Candesartan cilexetil 7.4
Quetiapine 7.3
cysteate 7.1
CIT 7.0
Memantine 7.0
CIT 6.9
DCL 6.9
TDP 6.9
galanthamine 6.8
Elan 6.7
Cardamine 6.6
Elan 6.4
1,2,3,6-tetrahydropyridine 6.4
1,2,3,6-tetrahydropyridine 6.4
CAA 6.2
Ubiquitin 6.2
Clozapine 6.1
Montelukast 6.1
IPD 6.1
Tacrine 6.0
APO 5.9
6-Hydroxydopamine 5.8
Xanthine 5.7
DAT 5.7
Dieldrin 5.7
DLA 5.6
Lorazepam 5.5
Clonazepam 5.5
Zolpidem 5.4
Ceftriaxone 5.4
Crocin 5.4
Baicalein 5.3
PDP 5.3
Sertraline 5.3
Amantadine 5.3
Amantadine 5.3
Eosin 5.2
Amantadine 5.2
Aripiprazole 5.2
Eosin 5.0
pentosidine 5.0
sparteine 4.9
Amantadine 4.9
Kallikrein 4.9
Thioflavin T 4.8
PPA 4.8
L-DOPA 4.8
Lovastatin 4.8
Lamotrigine 4.7
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 4.6
Rotenone 4.6
HMM 4.5
CHIP 4.5
2-nonenal 4.5
HVA 4.5
Hematoxylin 4.5
Olanzapine 4.4
quinazoline 4.4
quinazoline 4.4
Neuronal 4.4
Neurotensin 4.3
SPM 4.3
Corticosterone 4.3
MPTP 4.2
Haloperidol 4.2
Trehalose 4.2
HCI 4.0
Glycogen synthase 4.0
coenzyme Q10 4.0
Haloperidol 4.0
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