Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0752347 (Dementia with Lewy bodies)
 1,653 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
alpha-synuclein 332
synuclein 206
Sep 95
ubiquitin 86
amyloid precursor protein 76
MRI 51
Mol 37
prion 36
olfactory 36
dopamine transporter 35
tau protein 33
TGF-beta 31
TDP-43 28
glucocerebrosidase 28
APOE 27
axonal 24
tyrosine hydroxylase 24
FDG 23
apolipoprotein E 23
acetylcholinesterase 23
proteasome 23
SNCA 20
LBD 20
REM 20
LRRK2 18
CA2 18
Cholinesterase 18
CIT 18
FTD 18
She 17
CSF 17
dream 14
amyloid beta 14
parkin 13
14-3-3 13
APP 13
prion protein 13
CA1 12
MSA 12
glial fibrillary acidic protein 12
PSP 11
Ubiquitin 11
PrP 10
Apolipoprotein E 10
GBA1 10
beta-synuclein 9
neuronal protein 9
Parkin 8
DNA-binding protein 8
synaptophysin 8
PSEN1 8
LC3 8
esterase 7
ALS 7
endoplasmic reticulum 7
choline acetyltransferase 7
alpha synuclein 7
p62 7
PARK2 6
fused 6
SDS 6
PARK8 6
DJ-1 6
ATP 6
CBD 6
GRN 6
brain-derived neurotrophic factor 6
leucine-rich repeat kinase 2 6
cystatin C 6
TPPP/p25 5
CA3 5
cathepsin D 5
E3 ubiquitin ligase 5
insulin 5
huntingtin 5
catalase 5
CYP2D6 5
C9orf72 5
crystallin 5
ferritin 5
more...
Disease
Dementia with Lewy bodies 1653
dementia 913
Alzheimer's disease 903
Parkinson's disease 848
parkinsonism 283
cognitive impairment 193
hallucinations 178
progressive supranuclear palsy 150
depression 75
psychosis 68
delusions 56
Pick's disease 53
amyotrophic lateral sclerosis 48
REM sleep behavior disorder 43
plaque 42
Creutzfeldt-Jakob disease 39
Huntington's disease 36
behavior disorder 34
PDD 30
vascular disease 29
aphasia 25
movement disorder 23
delirium 23
apraxia 21
Multiple system atrophy 21
schizophrenia 21
encephalopathy 21
brain atrophy 20
LBD 20
sleep disorders 19
motor neuron disease 18
Gaucher disease 18
Vascular dementia 17
dysautonomia 16
memory impairment 15
Down syndrome 15
confusion 14
stroke 14
akinesia 12
MSA 12
hypertension 12
pneumonia 11
PSP 11
parasomnia 11
FTLD 11
PAF 10
dysphagia 10
Frontotemporal dementia 10
neurological disease 10
senile dementia 10
hydrocephalus 9
disinhibition 8
sleep disturbances 8
multiple sclerosis 8
major depressive disorder 7
incontinence 7
agnosia 7
dyskinesia 7
sleep apnea 7
amyloidosis 6
epilepsy 6
cognitive deficit 6
diabetes 6
PARK2 6
amnesia 6
bipolar disorder 6
neuroblastoma 6
SDS 6
CJD 6
CAA 5
disorientation 5
mental illness 5
multiple disorders 5
incontinence 4
leukoencephalopathy 4
CAA 4
aggression 4
ventricular dilatation 4
spongiform encephalopathy 4
PARK8 4
more...
Symptom
tremor 65
bradykinesia 24
agitation 21
dystonia 21
visual hallucination 20
apathy 19
myoclonus 14
memory loss 11
constipation 10
syncope 10
ataxia 10
sleepiness 9
anosmia 6
weakness 6
pain 5
fatigue 4
Psychiatric symptoms 4
catatonia 4
cerebellar ataxia 3
nausea 3
chorea 3
insomnia 3
dizziness 3
dysarthria 3
vomiting 3
seizures 2
thinning 2
spasticity 2
respiratory distress 2
anorexia 2
Visual symptoms 2
muscle rigidity 2
Behavioral symptoms 2
Retropulsion 2
ophthalmoplegia 2
paresis 2
blepharospasm 2
motor symptom 2
headache 2
dysuria 2
Involuntary Movement 1
Postural tremor 1
Rest tremor 1
Poor sleep 1
snoring 1
hypersomnia 1
asterixis 1
Fluctuation 1
Extrapyramidal rigidity 1
athetosis 1
personality change 1
spasm 1
metamorphopsia 1
paraparesis 1
Gastrointestinal symptoms 1
physical symptom 1
eds 1
Hemiballism 1
numbness 1
stridor 1
leg pain 1
lethargy 1
Depressive symptoms 1
stigma 1
auditory hallucination 1
cough 1
abnormal gait 1
vertigo 1
diarrhea 1
cachexia 1
abdominal pain 1
sneezing 1
clumsiness 1
dyspnea 1
Drug
CSF 17
Donepezil 9
Parkin 8
Parkin 8
Frontal 8
ROC 5
vitamin E 4
lysine 4
Spectrum 2
ascorbate 2
MDS 2
Heme 2
Fluorescein 2
Leaf 2
Portal 2
Azilect 2
Paraffin 2
ROS 1
lactose 1
Xanthium 1
Mazindol 1
Rotigotine 1
Triclosan 1
Vitamin E 1
CFT 1
Phenytoin 1
HCH 1
Vitamin B 1
caffeine 1
NADH 1
Monit 1
IL-2 1
PPA 1
Tianeptine 1
Gluconolactone 1
Escitalopram 1
Pramipexole 1
Modafinil 1
Pramipexole 1
Exametazime 1
Vitamin B12 1
Lovastatin 1
Aricept 1
citric acid 1
ETS 1
Domin 1
IPD 1
Enzyme
acetylcholinesterase 73
cholinesterase 57
proteasome 25
tyrosine hydroxylase 23
glucocerebrosidase 22
mitogen-activated protein kinase 11
ERK 10
proteinase K 8
choline acetyltransferase 7
protein kinase 7
superoxide dismutase 6
monoamine oxidase 6
complex I 6
catalase 5
cathepsin D 4
caspase-3 4
DAT 4
isopeptidase 4
enolase 3
focal adhesion kinase 3
Thy1 3
trypsin 3
phospholipase A2 2
prolyl endopeptidase 2
calcineurin 2
cathepsin B 2
protein kinase C 2
tryptophan hydroxylase 2
phospholipase C 2
GSK 2
CYP3A4 2
MEK 2
gamma-glutamyl transpeptidase 2
protein phosphatase 2A 2
PARP 2
glutathione peroxidase 2
MEKK1 2
cytochrome oxidase 1
CPT 1
ornithine decarboxylase 1
AMP-activated protein kinase 1
ACE 1
glutathione reductase 1
caspase-2 1
CPR 1
ubiquitin-protein ligase 1
pyruvate dehydrogenase 1
thrombin 1
alanine aminotransferase 1
hexosaminidase 1
caspase-9 1
pyruvate dehydrogenase 1
insulin-degrading enzyme 1
beta-secretase 1
IKK 1
cathepsin H 1
pyruvate dehydrogenase 1
PTA 1
ATPase 1
tryptase 1
GRK2 1
ACS 1
GRK5 1
caspase-2 1
chymotrypsin 1
NOS 1
CaMKII 1
endothelin-converting enzyme 1
CPT 1
phospholipid:diacylglycerol acyltransferase 1
beta-galactosidase 1
NADPH oxidase 1
creatine kinase 1
alpha-mannosidase 1
neurosin 1
DAP II 1
heparinase 1
mannanase 1
NADPH oxidase 1
BAL 1
more...
Compound
Clin 105
Dec 97
DNA 29
iron 26
glucose 22
CIT 18
CIT 18
calcium 16
glutamate 14
L-DOPA 13
oxygen 12
Neuronal 12
PSP 11
silver 10
Ubiquitin 10
hydrogen 9
DSM 9
His 9
iodine 8
formic acid 7
formic acid 7
formic acid 7
Rivastigmine 7
formic acid 7
formic acid 7
formic acid 7
serine 7
formic acid 7
formic acid 7
Dopamine 7
formic acid 7
formic acid 7
TDP 6
Clozapine 6
water 6
SDS 6
methionine 6
tyrosine 6
ATP 6
copper 5
MPTP 5
manganese 5
GSH 5
GSH 5
valine 4
threonine 4
galactose 4
APO 4
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 4
Memantine 4
galanthamine 4
DAT 4
nitrogen 4
Cereb 4
TNF 4
CAA 4
5-HT 4
NMDA 4
lysine 4
Quetiapine 4
cysteine 4
ACh 4
leucine 3
formaldehyde 3
GABA 3
phosphate 3
GABA 3
alanine 3
sulfate 3
creatinine 3
sodium 3
methyl carbamate 3
Hematoxylin 3
noradrenaline 3
PGA 2
Heme 2
zinc 2
Eosin 2
urea 2
Asp 2
more...