Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0752347 (
Dementia with Lewy bodies
)
1,653
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
alpha-synuclein
332
synuclein
206
Sep
95
ubiquitin
86
amyloid precursor protein
76
MRI
51
Mol
37
olfactory
36
prion
36
dopamine transporter
35
tau protein
33
TGF-beta
31
glucocerebrosidase
28
TDP-43
28
APOE
27
tyrosine hydroxylase
24
axonal
24
acetylcholinesterase
23
FDG
23
apolipoprotein E
23
proteasome
23
SNCA
20
LBD
20
REM
20
CIT
18
FTD
18
Cholinesterase
18
CA2
18
LRRK2
18
She
17
CSF
17
amyloid beta
14
dream
14
parkin
13
14-3-3
13
prion protein
13
APP
13
MSA
12
glial fibrillary acidic protein
12
CA1
12
more...
Disease
Dementia with Lewy bodies
1653
dementia
913
Alzheimer's disease
903
Parkinson's disease
848
parkinsonism
283
cognitive impairment
193
hallucinations
178
progressive supranuclear palsy
150
depression
75
psychosis
68
delusions
56
Pick's disease
53
amyotrophic lateral sclerosis
48
REM sleep behavior disorder
43
plaque
42
Creutzfeldt-Jakob disease
39
Huntington's disease
36
behavior disorder
34
PDD
30
vascular disease
29
aphasia
25
delirium
23
movement disorder
23
apraxia
21
encephalopathy
21
schizophrenia
21
Multiple system atrophy
21
LBD
20
brain atrophy
20
sleep disorders
19
motor neuron disease
18
Gaucher disease
18
Vascular dementia
17
dysautonomia
16
Down syndrome
15
memory impairment
15
confusion
14
stroke
14
MSA
12
akinesia
12
more...
Symptom
tremor
65
bradykinesia
24
dystonia
21
agitation
21
visual hallucination
20
apathy
19
myoclonus
14
memory loss
11
ataxia
10
syncope
10
constipation
10
sleepiness
9
weakness
6
anosmia
6
pain
5
Psychiatric symptoms
4
fatigue
4
catatonia
4
cerebellar ataxia
3
dysarthria
3
dizziness
3
insomnia
3
nausea
3
chorea
3
vomiting
3
paresis
2
thinning
2
motor symptom
2
Visual symptoms
2
muscle rigidity
2
spasticity
2
dysuria
2
anorexia
2
Retropulsion
2
Behavioral symptoms
2
blepharospasm
2
seizures
2
ophthalmoplegia
2
respiratory distress
2
headache
2
more...
Drug
CSF
17
Donepezil
9
Parkin
8
Parkin
8
Frontal
8
ROC
5
vitamin E
4
lysine
4
Spectrum
2
ascorbate
2
MDS
2
Fluorescein
2
Leaf
2
Portal
2
Paraffin
2
Azilect
2
Heme
2
ROS
1
lactose
1
Xanthium
1
Mazindol
1
Rotigotine
1
Triclosan
1
Modafinil
1
Pramipexole
1
CFT
1
Vitamin B12
1
Vitamin B
1
caffeine
1
NADH
1
Monit
1
IL-2
1
PPA
1
Tianeptine
1
Gluconolactone
1
Escitalopram
1
Pramipexole
1
Lovastatin
1
Aricept
1
citric acid
1
more...
Enzyme
acetylcholinesterase
73
cholinesterase
57
proteasome
25
tyrosine hydroxylase
23
glucocerebrosidase
22
mitogen-activated protein kinase
11
ERK
10
proteinase K
8
protein kinase
7
choline acetyltransferase
7
complex I
6
superoxide dismutase
6
monoamine oxidase
6
catalase
5
caspase-3
4
DAT
4
isopeptidase
4
cathepsin D
4
enolase
3
Thy1
3
trypsin
3
focal adhesion kinase
3
prolyl endopeptidase
2
protein phosphatase 2A
2
MEK
2
CYP3A4
2
MEKK1
2
phospholipase C
2
phospholipase A2
2
GSK
2
gamma-glutamyl transpeptidase
2
cathepsin B
2
tryptophan hydroxylase
2
protein kinase C
2
calcineurin
2
PARP
2
glutathione peroxidase
2
tryptase
1
CPT
1
caspase-2
1
more...
Compound
Clin
105
Dec
97
DNA
29
iron
26
glucose
22
CIT
18
CIT
18
calcium
16
glutamate
14
L-DOPA
13
Neuronal
12
oxygen
12
PSP
11
Ubiquitin
10
silver
10
hydrogen
9
DSM
9
His
9
iodine
8
formic acid
7
formic acid
7
formic acid
7
formic acid
7
Rivastigmine
7
formic acid
7
formic acid
7
serine
7
formic acid
7
formic acid
7
formic acid
7
formic acid
7
Dopamine
7
SDS
6
methionine
6
water
6
TDP
6
tyrosine
6
Clozapine
6
ATP
6
MPTP
5
more...