Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0752347 (Dementia with Lewy bodies)
1,653 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
alpha-synuclein 332
synuclein 206
Sep 95
ubiquitin 86
amyloid precursor protein 76
MRI 51
Mol 37
olfactory 36
prion 36
dopamine transporter 35
tau protein 33
TGF-beta 31
glucocerebrosidase 28
TDP-43 28
APOE 27
tyrosine hydroxylase 24
axonal 24
acetylcholinesterase 23
FDG 23
apolipoprotein E 23
proteasome 23
SNCA 20
LBD 20
REM 20
CIT 18
FTD 18
Cholinesterase 18
CA2 18
LRRK2 18
She 17
CSF 17
amyloid beta 14
dream 14
parkin 13
14-3-3 13
prion protein 13
APP 13
MSA 12
glial fibrillary acidic protein 12
CA1 12
more...
Disease
Dementia with Lewy bodies 1653
dementia 913
Alzheimer's disease 903
Parkinson's disease 848
parkinsonism 283
cognitive impairment 193
hallucinations 178
progressive supranuclear palsy 150
depression 75
psychosis 68
delusions 56
Pick's disease 53
amyotrophic lateral sclerosis 48
REM sleep behavior disorder 43
plaque 42
Creutzfeldt-Jakob disease 39
Huntington's disease 36
behavior disorder 34
PDD 30
vascular disease 29
aphasia 25
delirium 23
movement disorder 23
apraxia 21
encephalopathy 21
schizophrenia 21
Multiple system atrophy 21
LBD 20
brain atrophy 20
sleep disorders 19
motor neuron disease 18
Gaucher disease 18
Vascular dementia 17
dysautonomia 16
Down syndrome 15
memory impairment 15
confusion 14
stroke 14
MSA 12
akinesia 12
more...
Symptom
tremor 65
bradykinesia 24
dystonia 21
agitation 21
visual hallucination 20
apathy 19
myoclonus 14
memory loss 11
ataxia 10
syncope 10
constipation 10
sleepiness 9
weakness 6
anosmia 6
pain 5
Psychiatric symptoms 4
fatigue 4
catatonia 4
cerebellar ataxia 3
dysarthria 3
dizziness 3
insomnia 3
nausea 3
chorea 3
vomiting 3
paresis 2
thinning 2
motor symptom 2
Visual symptoms 2
muscle rigidity 2
spasticity 2
dysuria 2
anorexia 2
Retropulsion 2
Behavioral symptoms 2
blepharospasm 2
seizures 2
ophthalmoplegia 2
respiratory distress 2
headache 2
more...
Drug
CSF 17
Donepezil 9
Parkin 8
Parkin 8
Frontal 8
ROC 5
vitamin E 4
lysine 4
Spectrum 2
ascorbate 2
MDS 2
Fluorescein 2
Leaf 2
Portal 2
Paraffin 2
Azilect 2
Heme 2
ROS 1
lactose 1
Xanthium 1
Mazindol 1
Rotigotine 1
Triclosan 1
Modafinil 1
Pramipexole 1
CFT 1
Vitamin B12 1
Vitamin B 1
caffeine 1
NADH 1
Monit 1
IL-2 1
PPA 1
Tianeptine 1
Gluconolactone 1
Escitalopram 1
Pramipexole 1
Lovastatin 1
Aricept 1
citric acid 1
more...
Enzyme
acetylcholinesterase 73
cholinesterase 57
proteasome 25
tyrosine hydroxylase 23
glucocerebrosidase 22
mitogen-activated protein kinase 11
ERK 10
proteinase K 8
protein kinase 7
choline acetyltransferase 7
complex I 6
superoxide dismutase 6
monoamine oxidase 6
catalase 5
caspase-3 4
DAT 4
isopeptidase 4
cathepsin D 4
enolase 3
Thy1 3
trypsin 3
focal adhesion kinase 3
prolyl endopeptidase 2
protein phosphatase 2A 2
MEK 2
CYP3A4 2
MEKK1 2
phospholipase C 2
phospholipase A2 2
GSK 2
gamma-glutamyl transpeptidase 2
cathepsin B 2
tryptophan hydroxylase 2
protein kinase C 2
calcineurin 2
PARP 2
glutathione peroxidase 2
tryptase 1
CPT 1
caspase-2 1
more...
Compound
Clin 105
Dec 97
DNA 29
iron 26
glucose 22
CIT 18
CIT 18
calcium 16
glutamate 14
L-DOPA 13
Neuronal 12
oxygen 12
PSP 11
Ubiquitin 10
silver 10
hydrogen 9
DSM 9
His 9
iodine 8
formic acid 7
formic acid 7
formic acid 7
formic acid 7
Rivastigmine 7
formic acid 7
formic acid 7
serine 7
formic acid 7
formic acid 7
formic acid 7
formic acid 7
Dopamine 7
SDS 6
methionine 6
water 6
TDP 6
tyrosine 6
Clozapine 6
ATP 6
MPTP 5
more...