Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0752347 (Dementia with Lewy bodies)
 1,653 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
alpha-synuclein 332
synuclein 206
Sep 95
ubiquitin 86
amyloid precursor protein 76
MRI 51
Mol 37
prion 36
olfactory 36
dopamine transporter 35
tau protein 33
TGF-beta 31
glucocerebrosidase 28
TDP-43 28
APOE 27
axonal 24
tyrosine hydroxylase 24
FDG 23
proteasome 23
acetylcholinesterase 23
apolipoprotein E 23
LBD 20
REM 20
SNCA 20
CIT 18
Cholinesterase 18
LRRK2 18
CA2 18
FTD 18
She 17
CSF 17
amyloid beta 14
dream 14
parkin 13
APP 13
14-3-3 13
prion protein 13
MSA 12
glial fibrillary acidic protein 12
CA1 12
PSP 11
Ubiquitin 11
GBA1 10
Apolipoprotein E 10
PrP 10
neuronal protein 9
beta-synuclein 9
Parkin 8
synaptophysin 8
PSEN1 8
DNA-binding protein 8
LC3 8
ALS 7
esterase 7
choline acetyltransferase 7
p62 7
endoplasmic reticulum 7
alpha synuclein 7
CBD 6
GRN 6
SDS 6
brain-derived neurotrophic factor 6
PARK2 6
leucine-rich repeat kinase 2 6
PARK8 6
fused 6
DJ-1 6
cystatin C 6
ATP 6
C9orf72 5
cathepsin D 5
insulin 5
ferritin 5
TPPP/p25 5
IL-6 5
huntingtin 5
crystallin 5
catalase 5
CA3 5
CYP2D6 5
E3 ubiquitin ligase 5
neurotrophic factor 4
caspase-3 4
14-3-3 protein 4
PGP 9.5 4
tumor necrosis factor 4
SNCB 4
TNF 4
PINK1 4
NMDA receptor 4
MAP2 4
PSEN2 4
Iba1 4
muscarinic receptor 4
MAO-B 4
GSH 4
apolipoprotein 4
APO 4
SOD 4
synphilin-1 4
DAT 4
ubiquitin C-terminal hydrolase 4
ERK 4
progranulin 4
neurofilament protein 4
ANOVA 4
butyrylcholinesterase 4
NMR 4
microtubule-associated protein 4
with Parkinsonism 3
collagen 3
PARK7 3
HLA-DR 3
Bcl-2 3
superoxide dismutase 3
amyloid protein 3
ERK1 3
calbindin 3
gamma-synuclein 3
enolase 3
Visinin-like protein 1 3
extracellular protein 3
p53 3
CD4 3
AChE 3
CA4 3
MRS 3
GSD 3
COMT 3
TAU 3
GABA 3
NACP 3
PDGF 3
TPPP 3
NUB1 3
SNAP 3
5-HT2A 3
UTR 3
MAPK 3
metabotropic glutamate receptor 3
SORL1 3
interferon 3
cytokine 3
FUS 3
TAR DNA-binding protein 43 3
p38 3
glutamate receptor 3
dentatorubral-pallidoluysian atrophy 2
PSD-95 2
cAMP response element-binding protein 2
proline-rich 2
hemoglobin 2
vimentin 2
Proteinase 2
nitric oxide synthase 2
alpha, beta 2
alternatively spliced 2
MDS 2
cathepsin B 2
lipopolysaccharide 2
ERK2 2
NOTCH3 2
phospholipase A2 2
histone 2
PARP 2
cyclin-dependent kinase 5 2
mitogen-activated protein 2
ICD 2
Met 2
Cu/Zn superoxide dismutase 2
SOD1 2
cytochrome c oxidase 2
C18 2
CR3 2
histone deacetylase 2
C-reactive protein 2
TLR2 2
MEKK 2
glutathione peroxidase 2
HTT 2
eIF4E 2
small GTPase 2
X-linked 2
parvalbumin 2
SYN 2
jerky 2
VAMP-2 2
PTEN 2
ABCA7 2
CD68 2
ALB 2
GTPase 2
c-Jun 2
serum albumin 2
AMBRA1 2
tyrosine kinase 2
TMEM106B 2
Beclin-1 2
polypeptide 2
ECD 2
alpha 4 2
asymmetrical 2
Glucocerebrosidase 2
membrane-bound 2
Polymerase 2
CD95 2
PICALM 2
FGF 2
nuclear protein 2
LAMP-2 2
neuron-specific enolase 2
Metalloproteinase 2
tRNA 2
microtubule associated protein 2
myelin basic protein 2
phosphoprotein 2
CML 2
substance P 2
pyruvate dehydrogenase 2
somatostatin 2
PDB 2
brain-derived 2
HLA 2
B12 2
cytochrome P450 2
CREB 2
BACE1 2
CYP3A4 2
housekeeping 2
ART 2
JNK 2
peptidase 2
vesicular monoamine transporter 2 2
MAP kinase 2
nerve growth factor 2
PDC 2
ATP13A2 2
cathepsin 2
HDS 2
phosphatase 2
Pol 2
LAMP-1 2
nicotinic acetylcholine receptor 2
Net 2
cell surface protein 2
TOF 2
neurosin 2
tryptophan hydroxylase 2
Proteasome 2
BIN1 2
heme oxygenase-1 2
MET 1
COL4A2 1
ras 1
GABARAP 1
cholecystokinin 1
beclin 1 1
imiglucerase 1
platelet-derived growth factor 1
calpain 1
serine/threonine kinase 1
MEG 1
mTOR 1
cytoskeletal protein 1
PPAR 1
OGF 1
CEL 1
PGC 1
ubiquitin-like protein 1
GRK5 1
dipeptidyl aminopeptidase-like protein 6 1
PLB 1
LMP 1
transcription repressor 1
CD16) 1
lipid-binding protein 1
CD25 1
GPT 1
CD44 1
ubiquitin-protein ligase 1
Bcl-X 1
KCNMB2 1
CYP3A7 1
neurotrophin 1
ASH1L 1
AMP-activated protein kinase 1
heparin-binding epidermal growth factor-like growth factor 1
beta-actin 1
p65 1
COPD 1
RUFY3 1
PLA2G6 1
Huntingtin 1
ALD 1
MGC 1
CASS4 1
EIF4G1 1
calcium channel 1
EA6 1
PPARGC1A 1
GLT1 1
San 1
Gen 1
RRM1 1
FOXP2 1
5-lipoxygenase 1
IL-4 1
glutathione reductase 1
MS4A6A 1
annexin V 1
API 1
PAR-2 1
UCH-L1 1
IL-1 beta 1
UCHL1 1
EPA 1
IgA 1
ubiquitin carboxyl-terminal hydrolase 1
transglutaminase 2 1
cytochrome 1
more...
Disease
Dementia with Lewy bodies 1653
dementia 913
Alzheimer's disease 903
Parkinson's disease 848
parkinsonism 283
cognitive impairment 193
hallucinations 178
progressive supranuclear palsy 150
depression 75
psychosis 68
delusions 56
Pick's disease 53
amyotrophic lateral sclerosis 48
REM sleep behavior disorder 43
plaque 42
Creutzfeldt-Jakob disease 39
Huntington's disease 36
behavior disorder 34
PDD 30
vascular disease 29
aphasia 25
delirium 23
movement disorder 23
Multiple system atrophy 21
schizophrenia 21
apraxia 21
encephalopathy 21
LBD 20
brain atrophy 20
sleep disorders 19
Gaucher disease 18
motor neuron disease 18
Vascular dementia 17
dysautonomia 16
Down syndrome 15
memory impairment 15
confusion 14
stroke 14
akinesia 12
hypertension 12
MSA 12
pneumonia 11
PSP 11
FTLD 11
parasomnia 11
dysphagia 10
neurological disease 10
senile dementia 10
Frontotemporal dementia 10
PAF 10
hydrocephalus 9
sleep disturbances 8
multiple sclerosis 8
disinhibition 8
agnosia 7
dyskinesia 7
incontinence 7
sleep apnea 7
major depressive disorder 7
neuroblastoma 6
CJD 6
SDS 6
cognitive deficit 6
amyloidosis 6
bipolar disorder 6
diabetes 6
PARK2 6
amnesia 6
epilepsy 6
disorientation 5
mental illness 5
multiple disorders 5
CAA 5
CAA 4
ventricular dilatation 4
GSH 4
Cranial nerves 4
cardiovascular disease 4
cognitive disorder 4
incontinence 4
PARK8 4
narcolepsy 4
aggression 4
Corticobasal degeneration 4
Posterior 4
leukoencephalopathy 4
spongiform encephalopathy 4
Cranial nerves 4
restless legs syndrome 4
Bielschowsky 4
cold 4
cancer 4
olivopontocerebellar atrophy 4
Pure autonomic failure 4
encephalitis 4
migraine 3
PARK7 3
neurogenic bladder 3
sarcoma 3
FUS 3
renal failure 3
atherosclerosis 3
B-cell lymphoma 3
Hallervorden-Spatz disease 3
hypothyroidism 3
degenerative disease 3
MRS 3
mania 3
aggressiveness 3
bronchopneumonia 3
Capgras syndrome 3
dehydration 3
tumor 3
scrapie 3
BPSD 3
Neurodegenerative Disorders 3
posttraumatic stress disorder 3
primary lateral sclerosis 3
stereotypies 2
Pseudodementia 2
muscular atrophy 2
hyperlipidemia 2
agraphia 2
hypersexuality 2
suicide attempts 2
myelodysplastic syndrome 2
hallucinosis 2
hemiparesis 2
language disorder 2
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy 2
paranoia 2
Tourette syndrome 2
Whipple's disease 2
alcoholism 2
multi-infarct dementia 2
alexia 2
Hashimoto's thyroiditis 2
ICD 2
Dementia in Parkinson's disease 2
presenile dementia 2
mole 2
aspiration pneumonia 2
Wilson's disease 2
pseudobulbar palsy 2
MDS 2
Meige syndrome 2
glioma 2
kuru 2
cataplexy 2
HIV encephalitis 2
memory disorder 2
mole 2
myasthenia gravis 2
immunodeficiency 2
celiac disease 2
varices 2
chronic obstructive pulmonary disease 2
bradyarrhythmia 2
amnesic syndrome 2
SPM 2
agranulocytosis 2
Progressive dementia 2
HIV 2
thrombocytopenia 2
colon cancer 2
chronic myeloid leukemia 2
autoimmune disease 2
ischemia 2
coma 2
leukemia 2
herpes 2
autism 2
cerebral infarction 2
ADHD 2
anemia 2
leprosy 2
hypochondriasis 2
PDC 2
liver disease 2
cytomegalovirus 2
myocardial infarction 2
visual dysfunction 2
Epstein 2
astrocytoma 2
Demented 2
metabolic syndrome 2
MCD 1
dyscalculia 1
Charcot-Marie-Tooth disease 1
progeria 1
hypercholesterolemia 1
varicella 1
Fabry 1
peptic ulcer 1
anhidrosis 1
unipolar depression 1
KRS 1
MAS 1
PDP 1
Plaque 1
pruritus 1
carcinoid syndrome 1
psychological stress 1
Secondary parkinsonism 1
trismus 1
heart disease 1
congestive heart failure 1
sepsis 1
leukodystrophy 1
obsessive-compulsive disorder 1
gastric cancer 1
stuttering 1
myopathy 1
subarachnoid hemorrhage 1
anxiety disorders 1
Ludwig 1
worms 1
Sundowning 1
familial Alzheimer disease 1
acalculia 1
Mycoplasma 1
tardive dyskinesia 1
familial disorder 1
borderline personality disorder 1
abnormal involuntary movements 1
Balint's syndrome 1
Larynx 1
Kluver-Bucy syndrome 1
early disease onset 1
Ewing's sarcoma 1
impulse control disorder 1
Goldstein 1
retinopathy 1
IBM 1
induced psychosis 1
Diffuse large B-cell lymphoma 1
AIDS dementia complex 1
sexual dysfunction 1
chronic disease 1
tuberculosis 1
CARASIL 1
diphtheria 1
suicide 1
panic attacks 1
fibromyalgia 1
pathological emotionality 1
CADASIL 1
major depressive episode 1
brain disorder 1
PARK1 1
Dystonia 1
PARK5 1
dysphoria 1
erectile dysfunction 1
HCI 1
Gerstmann 1
ALD 1
sick sinus syndrome 1
LAD 1
alcohol use disorder 1
neuritis 1
Bone lesion 1
hyperphagia 1
Cotard's syndrome 1
anhedonia 1
Hippocampal sclerosis 1
Rosenthal 1
measles 1
nystagmus 1
Pisa syndrome 1
forgetting 1
brain dysfunction 1
neutropenia 1
Lyme disease 1
tumor growth 1
type 2 diabetes 1
obstructive sleep apnea 1
Canavan 1
TCP 1
arteriopathy 1
breast cancer 1
disseminated intravascular coagulation 1
PARK6 1
acute myocardial infarction 1
acute disease 1
glioblastoma 1
pathological gambling 1
PARK11 1
myocardial ischemia 1
alcohol abuse 1
Poland 1
deafness 1
extrapyramidal disorder 1
iron overload 1
DWI 1
liver fibrosis 1
anguish 1
folate deficiency 1
meningioma 1
dysphasia 1
impotence 1
paranoid schizophrenia 1
psychogenic disorders 1
terminal disease 1
Parkinson's disease and parkinsonism 1
tuberculous pleurisy 1
brain anoxia 1
Charles Bonnet syndrome 1
familial adenomatous polyposis 1
Larynx 1
conduct disorder 1
PARK13 1
sepsis 1
abdominal aortic aneurysm 1
progressive muscular atrophy 1
Larynx 1
Niemann-Pick 1
Brissaud 1
Primary Progressive Aphasia 1
West 1
more...
Symptom
tremor 65
bradykinesia 24
agitation 21
dystonia 21
visual hallucination 20
apathy 19
myoclonus 14
memory loss 11
constipation 10
syncope 10
ataxia 10
sleepiness 9
anosmia 6
weakness 6
pain 5
fatigue 4
Psychiatric symptoms 4
catatonia 4
cerebellar ataxia 3
nausea 3
chorea 3
insomnia 3
dizziness 3
dysarthria 3
vomiting 3
seizures 2
thinning 2
spasticity 2
respiratory distress 2
anorexia 2
Visual symptoms 2
muscle rigidity 2
Behavioral symptoms 2
Retropulsion 2
ophthalmoplegia 2
paresis 2
blepharospasm 2
motor symptom 2
headache 2
dysuria 2
Involuntary Movement 1
Postural tremor 1
Rest tremor 1
Poor sleep 1
snoring 1
hypersomnia 1
asterixis 1
Fluctuation 1
Extrapyramidal rigidity 1
athetosis 1
personality change 1
spasm 1
metamorphopsia 1
paraparesis 1
Gastrointestinal symptoms 1
physical symptom 1
eds 1
Hemiballism 1
numbness 1
stridor 1
leg pain 1
lethargy 1
Depressive symptoms 1
stigma 1
auditory hallucination 1
cough 1
abnormal gait 1
vertigo 1
diarrhea 1
cachexia 1
abdominal pain 1
sneezing 1
clumsiness 1
dyspnea 1
Drug
CSF 17
Donepezil 9
Parkin 8
Parkin 8
Frontal 8
ROC 5
vitamin E 4
lysine 4
Spectrum 2
ascorbate 2
MDS 2
Heme 2
Fluorescein 2
Leaf 2
Portal 2
Azilect 2
Paraffin 2
ROS 1
lactose 1
Xanthium 1
Mazindol 1
Rotigotine 1
Triclosan 1
Vitamin E 1
CFT 1
Phenytoin 1
HCH 1
Vitamin B 1
caffeine 1
NADH 1
Monit 1
IL-2 1
PPA 1
Tianeptine 1
Gluconolactone 1
Escitalopram 1
Pramipexole 1
Modafinil 1
Pramipexole 1
Exametazime 1
Vitamin B12 1
Lovastatin 1
Aricept 1
citric acid 1
ETS 1
Domin 1
IPD 1
Enzyme
acetylcholinesterase 73
cholinesterase 57
proteasome 25
tyrosine hydroxylase 23
glucocerebrosidase 22
mitogen-activated protein kinase 11
ERK 10
proteinase K 8
choline acetyltransferase 7
protein kinase 7
complex I 6
monoamine oxidase 6
superoxide dismutase 6
catalase 5
cathepsin D 4
DAT 4
isopeptidase 4
caspase-3 4
enolase 3
focal adhesion kinase 3
Thy1 3
trypsin 3
phospholipase A2 2
prolyl endopeptidase 2
protein phosphatase 2A 2
calcineurin 2
cathepsin B 2
protein kinase C 2
tryptophan hydroxylase 2
phospholipase C 2
GSK 2
CYP3A4 2
MEK 2
gamma-glutamyl transpeptidase 2
PARP 2
glutathione peroxidase 2
MEKK1 2
cytochrome oxidase 1
CPT 1
ornithine decarboxylase 1
AMP-activated protein kinase 1
ACE 1
glutathione reductase 1
caspase-2 1
CPR 1
ubiquitin-protein ligase 1
pyruvate dehydrogenase 1
thrombin 1
alanine aminotransferase 1
hexosaminidase 1
caspase-9 1
insulin-degrading enzyme 1
kallikrein 1
beta-secretase 1
diaphorase 1
IKK 1
cathepsin H 1
pyruvate dehydrogenase 1
PTA 1
ATPase 1
tryptase 1
caspase-2 1
GRK2 1
ACS 1
GRK5 1
chymotrypsin 1
NOS 1
CaMKII 1
endothelin-converting enzyme 1
CPT 1
phospholipid:diacylglycerol acyltransferase 1
beta-galactosidase 1
NADPH oxidase 1
creatine kinase 1
pyruvate dehydrogenase 1
alpha-mannosidase 1
neurosin 1
DAP II 1
heparinase 1
mannanase 1
NADPH oxidase 1
BAL 1
CPT 1
mu-calpain 1
Compound
Clin 105
Dec 97
DNA 29
iron 26
glucose 22
CIT 18
CIT 18
calcium 16
glutamate 14
L-DOPA 13
Neuronal 12
oxygen 12
PSP 11
Ubiquitin 10
silver 10
hydrogen 9
His 9
DSM 9
iodine 8
formic acid 7
formic acid 7
formic acid 7
formic acid 7
formic acid 7
serine 7
formic acid 7
Rivastigmine 7
formic acid 7
formic acid 7
formic acid 7
Dopamine 7
formic acid 7
water 6
TDP 6
ATP 6
tyrosine 6
Clozapine 6
methionine 6
SDS 6
GSH 5
copper 5
manganese 5
MPTP 5
GSH 5
cysteine 4
Quetiapine 4
Cereb 4
galanthamine 4
threonine 4
nitrogen 4
Memantine 4
TNF 4
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 4
APO 4
NMDA 4
DAT 4
lysine 4
ACh 4
5-HT 4
valine 4
galactose 4
CAA 4
methyl carbamate 3
formaldehyde 3
leucine 3
phosphate 3
noradrenaline 3
GABA 3
creatinine 3
GABA 3
alanine 3
sulfate 3
Hematoxylin 3
sodium 3
zinc 2
quinazoline 2
Heme 2
urea 2
salt 2
aldehyde 2
nitric oxide 2
HVA 2
Asp 2
Corticosterone 2
guanidine 2
arginine 2
Haloperidol 2
PGA 2
Eosin 2
Eosin 2
TOF 2
2-nonenal 2
Triton X-100 2
Haloperidol 2
potassium 2
aldehyde 2
cAMP 2
quinazoline 2
benzamide 2
coenzyme Q10 2
SPM 2
Retinal 2
aluminum 2
Ceftriaxone 2
HMM 1
Amantadine 1
GMP 1
PDP 1
IPD 1
DCL 1
ATF 1
DIC 1
Lovastatin 1
THE 1
CPT 1
5-HIAA 1
NADH 1
Gluconolactone 1
CoA 1
Ile 1
Elan 1
TCP 1
GTP 1
Lithium 1
BMC 1
Thioflavin T 1
CoQ 1
hexadecanedioic acid 1
cyanide 1
TCP 1
Trehalose 1
mercury 1
Baicalein 1
Amantadine 1
ethyl methylcarbamate 1
dUTP 1
Glycogen synthase 1
Melatonin 1
NAD 1
PPA 1
acridine 1
HCI 1
PMA 1
Montelukast 1
Ara-C 1
acetate 1
Lactate 1
hydroxide 1
Candesartan cilexetil 1
ACS 1
Amantadine 1
xylose 1
ANA 1
Tuberin 1
Risperidone 1
PAP 1
Cholesterol 1
Panam 1
DLA 1
GSSG 1
Cardamine 1
DPH 1
MK801 1
Crocin 1
Kallikrein 1
Aripiprazole 1
Zolpidem 1
nitrate 1
CHIP 1
NAD 1
Xanthine 1
Cocaine 1
Vitamin E 1
Dopa 1
glutamine 1
PEG 1
BAL 1
nicotinic acid 1
Amantadine 1
LSD 1
Thioflavine S 1
PPA 1
PMA 1
Maps 1
1,2,3,6-tetrahydropyridine 1
Elan 1
Dieldrin 1
DDE 1
TCP 1
ACS 1
glutamic acid 1
PAM 1
proline 1
nicotinamide 1
PAP 1
TSH 1
6-Hydroxydopamine 1
Clonazepam 1
Ara-C 1
Lamotrigine 1
IMP 1
isoleucine 1
Letter 1
retinol 1
Rotenone 1
Lorazepam 1
Olanzapine 1
aspartic acid 1
Carbidopa-levodopa 1
Hemoglobin 1
ANA 1
CPT 1
isoleucine 1
sparteine 1
N-acetylcysteine 1
Serine 1
MEK 1
Substance P 1
TCP 1
N-acetylaspartate 1
Donepezil hydrochloride 1
cysteate 1
A 3 1
A 71 1
GalNAc 1
1,2,3,6-tetrahydropyridine 1
Sertraline 1
DOPAC 1
Optimal 1
Malondialdehyde 1
ethanol 1
H2O2 1
caffeine 1
acetic acid 1
chlorobenzene 1
GPT 1
TAR 1
AMPA 1
Neurotensin 1
Tacrine 1
pentosidine 1