Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0752347 (
Dementia with Lewy bodies
)
1,653
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
alpha-synuclein
332
synuclein
206
Sep
95
ubiquitin
86
amyloid precursor protein
76
MRI
51
Mol
37
olfactory
36
prion
36
dopamine transporter
35
tau protein
33
TGF-beta
31
glucocerebrosidase
28
TDP-43
28
APOE
27
axonal
24
tyrosine hydroxylase
24
proteasome
23
FDG
23
apolipoprotein E
23
more...
Disease
Dementia with Lewy bodies
1653
dementia
913
Alzheimer's disease
903
Parkinson's disease
848
parkinsonism
283
cognitive impairment
193
hallucinations
178
progressive supranuclear palsy
150
depression
75
psychosis
68
delusions
56
Pick's disease
53
amyotrophic lateral sclerosis
48
REM sleep behavior disorder
43
plaque
42
Creutzfeldt-Jakob disease
39
Huntington's disease
36
behavior disorder
34
PDD
30
vascular disease
29
more...
Symptom
tremor
65
bradykinesia
24
dystonia
21
agitation
21
visual hallucination
20
apathy
19
myoclonus
14
memory loss
11
constipation
10
syncope
10
ataxia
10
sleepiness
9
anosmia
6
weakness
6
pain
5
fatigue
4
catatonia
4
Psychiatric symptoms
4
dizziness
3
cerebellar ataxia
3
more...
Drug
CSF
17
Donepezil
9
Parkin
8
Frontal
8
Parkin
8
ROC
5
vitamin E
4
lysine
4
Heme
2
Portal
2
Leaf
2
ascorbate
2
MDS
2
Azilect
2
Spectrum
2
Fluorescein
2
Paraffin
2
ROS
1
Tianeptine
1
Mazindol
1
more...
Enzyme
acetylcholinesterase
73
cholinesterase
57
proteasome
25
tyrosine hydroxylase
23
glucocerebrosidase
22
mitogen-activated protein kinase
11
ERK
10
proteinase K
8
protein kinase
7
choline acetyltransferase
7
superoxide dismutase
6
complex I
6
monoamine oxidase
6
catalase
5
isopeptidase
4
caspase-3
4
DAT
4
cathepsin D
4
enolase
3
focal adhesion kinase
3
more...
Compound
Clin
105
Dec
97
DNA
29
iron
26
glucose
22
CIT
18
CIT
18
calcium
16
glutamate
14
L-DOPA
13
oxygen
12
Neuronal
12
PSP
11
silver
10
Ubiquitin
10
His
9
hydrogen
9
DSM
9
iodine
8
formic acid
7
more...