Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0751781 (NOD)
 6,696 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
NOD 6600
insulin 704
cytokine 633
CD4 548
CD34 422
Mol 389
pyrin 388
Sep 381
CD8 377
lymphoid 266
NLRP3 225
TNF 219
IL-10 218
IFN 215
IL-18 210
thymus 204
IL-6 200
lipopolysaccharide 178
MHC 175
severe combined immunodeficiency 172
IFN-gamma 172
autoantigen 164
IL-4 154
TCR 153
tumor necrosis factor 146
interferon 146
IL-2 144
DNA-dependent protein kinase 136
CD25 134
CD38 129
CD45 128
noggin 128
NOD2 127
TLR4 122
HLA 119
chemokine 114
major histocompatibility complex 101
DRPLA 98
RIG-I 96
MHC class II 95
NOD1 95
CD44 92
ATP 91
collagen 89
ASC 87
LPS 86
CD133 86
gut 84
MAPK 82
IL-1 81
Caspase-1 77
IL-17 77
CD19 76
B10 75
caspase-3 74
p53 72
erythroid 71
IDDM 71
CXCR4 68
TLR2 67
T cell receptor 65
stem cell factor 61
Fas 58
MHC class I 57
AKT 56
CD40 56
NLRC4 54
CD28 54
PI3K 54
mTOR 52
interferon-gamma 51
proinsulin 50
IL-8 50
glutamic acid decarboxylase 50
TNF-alpha 50
thrombopoietin 50
AIM2 50
TGF-beta 50
SCA1 48
p38 48
CXCL12 48
thyroglobulin 48
catenin 48
DBA 47
GAD65 47
lacrimal 46
GM-CSF 46
p65 45
fibronectin 45
MyD88 45
endoplasmic reticulum 44
inducible nitric oxide synthase 44
osteogenic 44
Cytokine 44
interacting protein 43
THP 43
CD86 42
ERK 42
vascular endothelial growth factor 42
IL-3 41
CD24 41
ROS 41
CD11b 41
IL-2 receptor 40
VEGF 38
SCA2 38
C-type lectin 38
BCR 37
ICAM-1 37
STAT 36
hematopoietic stem and progenitor cells 36
CD80 36
CD14 36
interleukin-6 36
GAD 36
albumin 35
CD20 35
HLA-A2 35
SCA3 34
IL-15 34
interleukin-2 34
p21 34
STAT3 34
perforin 33
SCA6 33
NLRP1 33
Bcl-2 32
Nanog 32
APC 32
fused 32
adaptor protein 32
glucagon 31
CXCL10 31
OCT4 31
granulocyte-macrophage colony-stimulating factor 31
CTLA-4 31
PD-1 31
CD11c 30
CD31 30
tyrosine kinase 30
CAST 30
mouse) 30
thioredoxin 29
HSC 29
TLR7 29
RIP2 29
interleukin-18 29
apoptosis-associated speck-like protein containing a CARD 28
ubiquitin 28
aldehyde dehydrogenase 28
TLR9 28
CCR5 28
islet-specific glucose-6-phosphatase catalytic subunit-related protein 27
SCA7 27
histone 27
ERK1 27
granulocyte colony-stimulating factor 27
PD-L1 27
CD33 27
cytokine receptor 27
more...
Disease
NOD 6696
SCID 2266
diabetes 1528
cancer 918
tumor 917
type 1 diabetes 805
leukemia 358
tumor growth 282
autoimmune disease 264
breast cancer 175
acute myeloid leukemia 155
hyperglycemia 144
HIV 135
tumorigenesis 127
metastases 113
lymphoma 99
acute lymphoblastic leukemia 95
immunodeficiency 87
melanoma 82
virus infection 81
Leukemia 79
graft-versus-host disease 76
infectious diseases 75
tumor progression 74
carcinoma 74
multiple myeloma 69
prostate cancer 69
hepatocellular carcinoma 63
autoimmune thyroiditis 62
encephalomyelitis 61
sepsis 58
chronic myeloid leukemia 56
multiple sclerosis 56
sepsis 56
type 2 diabetes 55
arthritis 54
colitis 52
thyroiditis 52
systemic lupus erythematosus 50
adenocarcinoma 50
inflammatory bowel disease 50
obesity 49
Crohn's disease 49
DBA 48
colorectal cancer 48
SCA1 48
Machado-Joseph disease 47
atherosclerosis 45
rheumatoid arthritis 45
colon cancer 43
lung cancer 41
B-cell lymphoma 40
SCA2 38
ischemia 38
Infection 37
Epstein 37
GAD 36
Mycobacterium 35
glioblastoma 35
primary tumor 35
influenza 34
insulinoma 33
carcinogenesis 33
SCA6 33
Alzheimer's disease 33
APC 32
MCF 32
Hodgkin's disease 30
lupus 30
pancreatic cancer 30
squamous cell carcinoma 30
chronic lymphocytic leukemia 29
AIDS 28
myocardial infarction 27
leukemogenesis 27
lupus 27
SCA7 27
bacterial infection 27
viremia 27
stroke 26
ulcerative colitis 26
ovarian cancer 26
neuroblastoma 25
gastric cancer 25
cytomegalovirus 25
tuberculosis 25
gout 25
Blocking 24
hematologic malignancies 24
BDC 24
glioma 24
immune deficiency 24
malaria 24
osteosarcoma 23
aggressiveness 23
adult T-cell leukemia/lymphoma 23
sarcoma 22
chronic lymphocytic leukemia 22
cardiovascular disease 21
ABL 21
liver cancer 21
Parkinson's disease 20
lymphopenia 20
SCA17 19
acute leukemia 19
pneumonia 19
cerebral ischemia 19
asthma 18
solid tumor 18
renal disease 18
teratoma 18
xerostomia 17
myelodysplastic syndrome 17
T-cell acute lymphoblastic leukemia 17
primary biliary cirrhosis 17
sialadenitis 17
glioblastoma multiforme 17
minimal residual disease 17
glucose intolerance 16
brain tumor 16
hepatitis B 16
stomatitis 16
fatty liver 16
bladder cancer 16
renal cell carcinoma 16
Graves' disease 16
cold 16
Huntington's disease 16
anemia 15
liver disease 15
myeloid leukemia 15
thrombocytopenia 15
liver cancer 15
depression 15
plaque 15
mantle cell lymphoma 15
Burkitt's lymphoma 15
HGF 14
peritonitis 14
celiac disease 14
hepatitis C 14
liver fibrosis 14
diphtheria 14
heart failure 14
Hashimoto's thyroiditis 14
cervical cancer 14
childhood ALL 14
SDS 13
lung metastases 13
Legionella 13
herpes simplex 13
metabolic syndrome 13
Kaposi's sarcoma 13
SCA8 13
acute promyelocytic leukemia 13
hepatitis 13
lung carcinoma 13
myocarditis 13
Syndrome 13
NAME 13
more...
Symptom
ataxia 29
pain 28
cerebellar ataxia 18
dry eye 13
diarrhea 12
exhaustion 12
seizures 12
splenomegaly 11
functional recovery 10
tremor 8
weakness 7
chorea 7
hypothermia 7
starvation 7
pelvic pain 6
lethargy 5
respiratory distress 5
anesthesia 5
erythema 5
dyspnea 3
thinning 3
myoclonus 3
cachexia 3
dystonia 2
dysarthria 2
analgesia 2
spasticity 2
Neuropathic pain 2
ketonuria 2
paraparesis 2
HSA 2
memory loss 2
paresis 2
neurological disability 2
ophthalmoplegia 2
collapse 2
fatigue 2
Chronic pelvic pain syndrome 2
ataxic gait 2
Ataxic 1
hypercapnia 1
skin damage 1
sneezing 1
vertigo 1
overweight 1
emaciation 1
vomiting 1
fasciculation 1
nasal discharge 1
hepatomegaly 1
clumsiness 1
tachypnea 1
bladder pain 1
knee pain 1
bradykinesia 1
stigma 1
spasm 1
asthenia 1
tonic-clonic seizure 1
incoordination 1
Gastrointestinal symptoms 1
adenitis 1
hypotonia 1
leg edema 1
athetosis 1
apathy 1
night sweats 1
muscle stiffness 1
constipation 1
bone pain 1
bloating 1
arthralgia 1
Behavioral symptoms 1
male subfertility 1
flushing 1
acidity 1
Spotting 1
abnormal gait 1
headache 1
urinary frequency 1
Tandem gait 1
Scratch 1
general problem 1
disturbed balance 1
Drug
IFN-gamma 169
IL-2 144
Norplant 127
CSF 56
ROS 41
G-CSF 22
lysine 21
NaI 19
NaI 19
NaI 19
NaI 19
Dermatol 16
CTX 13
Cardiovasc 11
Silica 7
uPA 7
IL-11 7
G418 6
ABC 6
MAP 6
Rituximab 5
TAT 5
Monit 5
CTX 4
Imatinib 4
CTX 4
Glucagon 4
Gleevec 4
Ethanol 4
p75 4
Heme 4
ascorbate 3
anti-CD33 3
PDL 3
Fluorescein 3
Propofol 3
IL-1ra 3
RFP 3
BLyS 3
EE2 3
MDS 3
Fructose 3
ATV 3
CPT-11 3
NBT 3
IFN-beta 3
Anakinra 2
BCG vaccine 2
Simvastatin 2
Nitric Oxide 2
CDX 2
Doxycycline 2
Maltose 2
Denosumab 2
NVP 2
Gel 2
Albumin 2
Liraglutide 2
Taxol 2
CDX 2
Bifidobacterium 2
Herceptin 2
Copaxone 2
Alliance 2
Adriamycin 2
Areca 2
GEO 2
Bevacizumab 2
Lenalidomide 2
Dextran sulfate sodium 2
Emodin 2
lactose 2
Rosiglitazone 2
MRC 2
Mycophenolic acid 2
Indomethacin 2
DM1 2
Arsenic trioxide 2
Forskolin 2
Cetuximab 2
Emodin 2
Docetaxel 2
Auranofin 2
Asthma 2
Beta-2 2
Tuberculin 2
AZT 2
Rolipram 2
AZT 2
Alanine 2
Thyroglobulin 1
Rosuvastatin 1
CAM 1
Aliskiren 1
Cholic Acid 1
Exenatide 1
CaCl2 1
FAD 1
Phosphatidylserine 1
CCL 1
Lovastatin 1
Epoetin 1
SBT 1
CTC 1
Gelatin 1
Maltrin 1
ALA 1
Enrofloxacin 1
KGF 1
ICI 1
CaCl2 1
Irinotecan 1
THF 1
Asn 1
Panitumumab 1
Activin 1
Carbazeran 1
Ontak 1
Valerianae radix 1
Itraconazole 1
APD 1
Glycyrrhiza 1
Rebamipide 1
Ginseng 1
ADM 1
-deoxyadenosine 1
Pirfenidone 1
niacin 1
Humulin 1
Scopolamine 1
Ezetimibe 1
Calcipotriol 1
Ganciclovir 1
Tacrolimus 1
Campath 1
CaCl2 1
Ontak 1
Diamox 1
Adenosine triphosphate 1
Erlotinib 1
Leucin 1
ETS 1
BH4 1
Resovist 1
Palmitoyl 1
Radicicol 1
citric acid 1
ID2 1
Clopidogrel 1
Sorafenib 1
Angiotensin II 1
Adenosine deaminase 1
TEL 1
Compound 19 1
Parkin 1
Campath 1
Lactase 1
Estrogens 1
Apaziquone 1
CIA 1
more...
Enzyme
caspase-1 353
mitogen-activated protein kinase 159
ERK 148
focal adhesion kinase 96
luciferase 62
caspase-3 54
protein kinase 37
APC 35
aldehyde dehydrogenase 33
aldehyde dehydrogenase 29
aldehyde dehydrogenase 28
aldehyde dehydrogenase 28
aldehyde dehydrogenase 28
superoxide dismutase 26
peroxidase 26
proteasome 26
AMP-activated protein kinase 23
thyroid peroxidase 22
IKK 21
alkaline phosphatase 21
lactate dehydrogenase 21
alanine aminotransferase 20
reverse transcriptase 20
PARP 19
aspartate aminotransferase 18
caspase-8 18
CD13 16
lysozyme 16
MEK 16
protein kinase C 15
ACS 15
cathepsin B 15
catalase 14
caspase-9 14
ALDH 14
NADPH oxidase 13
MDP 13
granzyme B 13
caspase-11 12
firefly luciferase 12
caspase-11 12
urokinase-type plasminogen activator 12
ATPase 11
AMPK 11
NADPH oxidase 11
AMPK 11
DNA methyltransferase 10
MIP 9
MMP 9
glutathione peroxidase 9
CD10 9
RNA polymerase 9
phosphoinositide 3-kinase 9
RNase 9
NO synthase 9
calcineurin 9
trypsin 8
P-glycoprotein 8
RNase 8
thymidine kinase 8
transcriptase 7
collagenase 7
thrombin 7
phosphatidylinositol 3-kinase 6
indoleamine 2,3-dioxygenase 6
transglutaminase 6
beta-glucuronidase 6
tyrosine hydroxylase 6
GSK 6
kinesin 6
glucose-6-phosphatase 6
TAT 5
AST 5
Thy1 5
prostate-specific membrane antigen 5
asparaginase 5
MDR 5
TSP-1 5
phosphoglycerate kinase 5
creatine kinase 5
phosphodiesterase 5
xanthine oxidase 4
tyrosinase 4
ACE 4
lipase 4
neutrophil elastase 4
renin 4
carboxypeptidase E 4
cdc2 4
neuraminidase 4
caspase-4 4
arginase 4
glyceraldehyde-3-phosphate dehydrogenase 4
DNA polymerase 4
caspase-4 4
CDR 4
phospholipase C 4
MMP-3 3
alpha-L-iduronidase 3
heme oxygenase 3
cathepsin S 3
glutamate decarboxylase 3
pepsin 3
MEKK1 3
fumarylacetoacetate hydrolase 3
beta-galactosidase 3
adenylate cyclase 3
caspase-7 3
PWD 3
caspase-7 3
MPP 3
glyceraldehyde-3-phosphate dehydrogenase 3
phosphoglucose isomerase 3
peptidylarginine deiminase 3
matrix metalloproteinase 2 2
dihydroorotate dehydrogenase 2
adenosine deaminase 2
glutathione reductase 2
glyceraldehyde-3-phosphate dehydrogenase 2
phospholipase A2 2
thioredoxin reductase 2
elastase 2
adenosine deaminase 2
isocitrate dehydrogenase 2
isocitrate dehydrogenase 2
hexosaminidase 2
ADP-ribosyltransferase 2
chymase 2
TdT 2
Pla 2
diaphorase 2
complex I 2
aldose reductase 2
hypoxanthine-guanine phosphoribosyltransferase 2
NQO1 2
glutamine synthetase 2
PDK1 2
SLB 2
glucose-6-phosphate dehydrogenase 2
caspase-5 2
inositol 3-kinase 2
glyceraldehyde-3-phosphate dehydrogenase 2
tryptase 2
adenosine kinase 2
phosphatidylinositol 4-kinase 2
Rex 2
cathepsin L 2
dihydrofolate reductase 2
STR 2
deoxyhypusine synthase 2
gamma-glutamylcysteine synthetase 2
thymidylate synthase 2
tissue plasminogen activator 2
HK2 2
apyrase 2
histidine kinase 2
glyceraldehyde-3-phosphate dehydrogenase 2
dipeptidyl peptidase IV 2
prostate-specific antigen 2
NOS 2
more...
Compound
Dec 491
DNA 338
Clin 311
glucose 290
TNF 219
oxygen 208
water 109
ATP 91
ASC 87
leucine 82
calcium 68
MDA 67
phosphate 59
Insulin 56
sodium 53
nitric oxide 51
iodine 50
DBA 47
DBA 47
DBA 47
THP 43
THP 43
NKT 41
tyrosine 40
BCR 37
nitrogen 37
sulfate 33
arginine 32
LTC4 32
retinoic acid 30
lysine 27
cysteine 26
nicotinamide 25
serine 24
vitamin D 22
STZ 22
PEG 22
ADP 22
DAP 21
Diazepam 21
ADP 21
ABL 21
ADP 21
alanine 21
DAP 21
ethanol 19
tryptophan 19
iron 19
potassium 18
methionine 17
MTT 16
zinc 16
PEG 16
acetate 16
ACS 15
NAD 15
ACS 15
salt 15
Thyroid 15
urea 14
Asp 14
cAMP 14
MEK 14
CTX 13
NAD 13
threonine 13
GM1 13
SDS 13
hydrogen 13
glutamate 12
glutamine 12
DMSO 11
His 11
TSH 11
proline 11
BCG 11
boron 11
galactose 10
tryptophan 10
GABA 10
AMP 10
copper 10
tryptophan 10
silicon 10
GSH 10
tryptophan 10
GSH 10
alloxan 10
GABA 9
FK506 9
ADP-ribose 9
H2O2 9
ASA 9
GMP 8
PMA 8
Hoechst 33342 8
Rapamycin 8
Hematoxylin 8
creatinine 8
Cyclosporine 8
CO2 7
N-acetylcysteine 7
palmitic acid 7
Adriamycin 7
Collagen 7
aspartic acid 7
hyaluronic acid 7
gamma-aminobutyric acid 6
aspartic acid 6
cGMP 6
aspartic acid 6
TEC 6
PMA 6
aluminum 6
ADR 6
dUTP 6
quinoline 6
TEM 6
aspartic acid 6
PGE2 6
Leucine 5
Neo 5
HPC 5
Optimal 5
RELA 5
DDP 5
TBP 5
MDR 5
glutamic acid 5
diacetate 5
GTP 5
5-FU 5
palmitic acid 5
ammonium 5
TBP 5
BCNU 5
silver 5
Quercetin 5
nitrate 5
PGA 5
HPC 5
manganese 5
MIA 4
acetic acid 4
Oil Red O 4
Colchicine 4
Oil Red O 4
Vitamin D 4
acetone 4
Retinal 4
Phe 4
asparagine 4
NPA 4
NADPH 4
DSS 4
NADPH 4
PGE 4
Cardiol 4
DHA 4
bis(2-chloroethyl) 4
more...