Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0751651 (mitochondrial disease)
 1,844 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MELAS 0.005
POLG 0.004
MERRF 0.003
EARS2 0.002
SURF1 0.001
EARS2 protein 0.001
sideroflexin 4 0.001
DNA polymerase gamma 0.001
LHON 0.001
C10orf2 0.001
MTND1 0.001
YARS2 0.001
C20orf7 0.001
complex I assembly factor 0.001
cytochrome c oxidase 0.001
GFM1 0.001
MTND6 0.001
METT11D1 0.001
C2orf64 0.001
NUCM 0.001
C1orf31 0.001
Succinate-CoA ligase, ADP-forming, beta subunit 0.001
PRO1853 0.001
CCDC44 0.001
TK2 protein 0.001
ATP6A 0.001
BOLA3 protein 0.001
FBXL4 0.001
COQ4 0.001
MTND3 0.001
MTATP6 0.001
NDUFAF1 0.001
ACAD9 0.001
SFRS8 0.001
MRPS22 0.001
ATP5SL 0.001
BCS1L 0.001
TTC19 0.001
RRM2B 0.000
SUCLA2 0.000
MT-ND5 0.000
F-box and leucine-rich repeat protein 4 0.000
mitochondrial ribosomal protein S23 0.000
CHCHD1 0.000
MRPS2 0.000
ADCK3 0.000
OXPHOS 0.000
tafazzin 0.000
polg 0.000
COQ9 0.000
GluRS 0.000
NARP 0.000
FOXRED1 0.000
TMEM70 0.000
COQ6 0.000
transmembrane protein 65 0.000
FARS2 0.000
pyruvate carboxylase, mitochondrial 0.000
MRPS28 0.000
TTC19 protein 0.000
POLG protein 0.000
LYRM7 0.000
MRPP1 0.000
NDUFA1 0.000
PDSS2 0.000
frataxin 0.000
tryptophan-tRNA ligase 0.000
PMPCA 0.000
tRNA 0.000
ATP12 0.000
Barth syndrome 0.000
NDUFA8 0.000
MTND4 0.000
TRIT1 0.000
COX6A 0.000
GALNT9 0.000
MT-ND4 0.000
FRDA 0.000
SURF-1 0.000
DARS2 0.000
GTPBP3 0.000
nucleotide binding protein-like 0.000
GPR172B 0.000
acyl-CoA dehydrogenase 9 0.000
ACN9 0.000
PPA2 0.000
ADCK4 0.000
PUS1 0.000
SCO2 0.000
NIPSNAP1 0.000
ATAD3C 0.000
Mitochondrial DNA polymerase gamma 0.000
PARS2 0.000
CABC1 0.000
NDUFA7 0.000
GK 2 0.000
SCAF1 0.000
ECGF1 0.000
SUCLG1 0.000
PDHA1 0.000
ATPIF1 0.000
VPS13D 0.000
SLC25A42 0.000
USMG5 0.000
MSTO1 0.000
NSUN3 0.000
TMEM126B 0.000
MT-ND3 0.000
SLC25A46 0.000
LONP1 0.000
Deoxyguanosine kinase 0.000
GatA 0.000
TRMU 0.000
protein of relevant evolutionary and lymphoid interest 0.000
MNGIE 0.000
NDUFS2 0.000
ETFB 0.000
COX15 0.000
MTND5 0.000
DGUOK 0.000
MTCYB 0.000
iron-sulfur protein 3 0.000
COX18 0.000
NDUFB8 0.000
MRPP2 0.000
NARS2 0.000
peroxisome proliferative activated receptor gamma 0.000
GBAS 0.000
mitochondrial ribosomal protein S12 0.000
ND6 0.000
NDUFS8 0.000
ND4 0.000
AGK 0.000
NDUFS3 0.000
COX 0.000
G protein-coupled receptor 35 0.000
NDUFC2 0.000
IARS2 0.000
FBN3 0.000
TSFM 0.000
NDUFAB1 0.000
COX7A2L 0.000
COX16 0.000
ATAD3A 0.000
ETHE1 0.000
NDUFS4 0.000
PDHB 0.000
NDUFB11 0.000
CLPB 0.000
RAB24 0.000
FASTKD2 0.000
NUBPL 0.000
PolB 0.000
MT-CO2 0.000
NDUFV1 0.000
TIM22 0.000
ETFA 0.000
PNPLA4 0.000
hUPF2 0.000
mitochondrial 3-oxoacyl-CoA thiolase 0.000
more...
Disease
mitochondrial disease 0.999
Leigh syndrome 0.008
MELAS 0.007
Leber's hereditary optic neuropathy 0.007
MELAS 0.006
mitochondrial myopathy 0.006
lactic acidosis 0.006
mitochondrial encephalomyopathy 0.005
MERRF 0.003
Alpers 0.003
Kearns-Sayre syndrome 0.003
Chronic progressive external ophthalmoplegia 0.002
Complex I deficiency 0.002
Pearson's syndrome 0.001
myopathy 0.001
myoclonus epilepsy 0.001
encephalopathy 0.001
Complex III deficiency 0.001
Barth syndrome 0.000
mental developmental delay 0.000
Metabolic cardiomyopathy 0.000
SCAE 0.000
Disorders of mitochondrial metabolism 0.000
ATP synthase deficiency 0.000
CMTX4 0.000
Idiopathic growth hormone deficiency 0.000
cardiomyopathy 0.000
MILS 0.000
deafness 0.000
FRDA 0.000
optic atrophy 0.000
Friedreich's ataxia 0.000
MEHMO 0.000
Cytochrome c oxidase deficiency 0.000
Cone dystrophy 0.000
sideroblastic anemia 0.000
MNGIE 0.000
Mitochondrial DNA depletion 0.000
Mitochondrial neurogastrointestinal encephalopathy 0.000
developmental delay 0.000
PDH deficiency 0.000
floppy baby syndrome 0.000
hypertrophic cardiomyopathy 0.000
Multiple symmetrical lipomatosis 0.000
epilepsy 0.000
3-Methylglutaconic aciduria 0.000
sensorineural hearing loss 0.000
DFNA4 0.000
neuropathy 0.000
prolapse 0.000
SPG7 0.000
leukoencephalopathy 0.000
failure to thrive 0.000
Fazio-Londe 0.000
encephalomyelopathy 0.000
Epilepsia partialis continua 0.000
stroke 0.000
leukodystrophy 0.000
Basal ganglia calcification 0.000
hyperlysinemia 0.000
basal ganglia disease 0.000
cholangiolitis 0.000
Brown-Vialetto-Van Laere syndrome 0.000
3p- syndrome 0.000
myofasciitis 0.000
Wolfram syndrome 0.000
Cortical blindness 0.000
Alternating hemiplegia of childhood 0.000
retinitis pigmentosa 0.000
Wiedemann-Rautenstrauch syndrome 0.000
FXTAS 0.000
OPA1 0.000
enzyme deficiency 0.000
status epilepticus 0.000
heart block 0.000
Dercum's disease 0.000
Pontocerebellar hypoplasia 0.000
Conduction disorders 0.000
Wolcott-Rallison syndrome 0.000
anarthria 0.000
hereditary chorea 0.000
primary disorders 0.000
Fanconi syndrome 0.000
Optic neuropathy 0.000
Kniest dysplasia 0.000
abdominal migraine 0.000
Fanconi 0.000
hereditary ataxia 0.000
Reye 0.000
peripheral neuropathy 0.000
ARTS 0.000
cardiofaciocutaneous syndrome 0.000
dilated cardiomyopathy 0.000
lipomatosis 0.000
macrocytic anemia 0.000
hyperprolinemia 0.000
Hypereosinophilia 0.000
Autoimmune encephalitis 0.000
aminoaciduria 0.000
acrocyanosis 0.000
diabetes 0.000
neuromuscular disorder 0.000
eye movement disorder 0.000
methylmalonic acidemia 0.000
gastrointestinal dysfunction 0.000
neurological disease 0.000
Ohtahara syndrome 0.000
Takotsubo syndrome 0.000
VATER association 0.000
grand mal epilepsy 0.000
X-linked sideroblastic anemia 0.000
Danon disease 0.000
X-linked retinoschisis 0.000
SBMA 0.000
retinopathy 0.000
Staphylococcus aureus endocarditis 0.000
polyneuropathy 0.000
mental retardation 0.000
common migraine 0.000
mental retardation 0.000
HDL1 0.000
blindness 0.000
Hypertrophic cardiomyopathy 0.000
MCAD deficiency 0.000
migraine 0.000
camptocormia 0.000
brain atrophy 0.000
spastic paraplegia 0.000
Autism spectrum disorder 0.000
IBM 0.000
EPI 0.000
movement disorder 0.000
Charcot-Marie-Tooth disease 0.000
MRS 0.000
muscular atrophy 0.000
malignant hyperthermia 0.000
propionic acidemia 0.000
Fahr's disease 0.000
borreliosis 0.000
hereditary fructose intolerance 0.000
Inborn errors of metabolism 0.000
galactosemia 0.000
PMD 0.000
learning disorder 0.000
fibroelastosis 0.000
Deafness 0.000
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy 0.000
Hypertrophic 0.000
delayed speech 0.000
chorioretinal atrophy 0.000
LMS 0.000
motor neuron disease 0.000
identity disorder 0.000
hemiplegic migraine 0.000
McArdle's disease 0.000
Menkes 0.000
respiratory failure 0.000
Focal segmental glomerulosclerosis 0.000
familial disorder 0.000
heart failure 0.000
more...
Symptom
ophthalmoplegia 0.002
Sensory ataxia 0.000
Ophthalmoparesis 0.000
hypotonia 0.000
ataxia 0.000
External ophthalmoplegia 0.000
benign congenital hypotonia 0.000
seizures 0.000
weakness 0.000
Ataxic 0.000
cerebellar ataxia 0.000
dysarthria 0.000
myoclonus 0.000
Cold intolerance 0.000
muscle cramps 0.000
dystonia 0.000
Exercise intolerance 0.000
fatigue 0.000
impaired motor coordination 0.000
myalgia 0.000
spasticity 0.000
hyperemesis 0.000
hepatomegaly 0.000
lethargy 0.000
clumsiness 0.000
ataxic gait 0.000
ketonuria 0.000
hyperoxia 0.000
tonic-clonic seizure 0.000
paraparesis 0.000
partial seizure 0.000
headache 0.000
tremor 0.000
anesthesia 0.000
blurred vision 0.000
neurological disability 0.000
DNA marker 0.000
chorea 0.000
dysesthesia 0.000
sleepiness 0.000
hypersomnia 0.000
Postoperative pain 0.000
abnormal gait 0.000
muscle stiffness 0.000
hypertonia 0.000
vomiting 0.000
fasciculation 0.000
cachexia 0.000
diarrhea 0.000
hypocapnia 0.000
incoordination 0.000
hemiplegia 0.000
hip pain 0.000
paresthesia 0.000
polydipsia 0.000
bradykinesia 0.000
pallor 0.000
constipation 0.000
paresis 0.000
asthenia 0.000
snoring 0.000
polyuria 0.000
dyspnea 0.000
neck pain 0.000
starvation 0.000
syncope 0.000
nausea and vomiting 0.000
hepatosplenomegaly 0.000
abdominal pain 0.000
numbness 0.000
ENT 0.000
exhaustion 0.000
analgesia 0.000
collapse 0.000
spasm 0.000
hypercapnia 0.000
respiratory distress 0.000
dizziness 0.000
nausea 0.000
thinning 0.000
pain 0.000
erythema 0.000
anorexia 0.000
chest pain 0.000
hypothermia 0.000
cough 0.000
overweight 0.000
Drug
Idebenone 0.000
NADH 0.000
EPI 0.000
ROS 0.000
Riboflavin 0.000
ISP 0.000
Parkin 0.000
Parkin 0.000
Sodium valproate 0.000
Caspofungin 0.000
CSF 0.000
Clofibrate 0.000
Kainic acid 0.000
Alliance 0.000
OTC 0.000
Rosiglitazone 0.000
OTC 0.000
DMAP 0.000
AZT 0.000
RFP 0.000
Apomorphine 0.000
Glutathione 0.000
BLM 0.000
AZT 0.000
Vitamin E 0.000
Mutagen 0.000
niacin 0.000
lysine 0.000
Propofol 0.000
MDS 0.000
TAT 0.000
FAD 0.000
ascorbate 0.000
Fluorescein 0.000
MRC 0.000
PCP 0.000
Fluorescein 0.000
Spectrum 0.000
Portal 0.000
citric acid 0.000
vitamin E 0.000
Asn 0.000
Nephron 0.000
ICI 0.000
Gel 0.000
EPA 0.000
ROC 0.000
Spectrum 0.000
Nephron 0.000
ENT 0.000
Leaf 0.000
caffeine 0.000
IL-2 0.000
Cardiovasc 0.000
Enzyme
complex I 0.002
cytochrome oxidase 0.000
succinate dehydrogenase 0.000
tRNA isopentenyltransferase 0.000
pyruvate dehydrogenase 0.000
sulfur dioxygenase 0.000
ATP synthase 0.000
acylglycerol kinase 0.000
GMP reductase 0.000
citrate synthase 0.000
glycerate kinase 0.000
pyruvate dehydrogenase 0.000
pyruvate dehydrogenase 0.000
NADH dehydrogenase 0.000
aspartyl-tRNA synthetase 0.000
rhomboid protease 0.000
DNA polymerase 0.000
tRNase Z 0.000
aconitase 0.000
deoxyguanosine kinase 0.000
RNase P 0.000
acyl-CoA dehydrogenase 0.000
thymidine phosphorylase 0.000
adenylosuccinate lyase 0.000
histidyl-tRNA synthetase 0.000
diaphorase 0.000
acyl-CoA dehydrogenase 0.000
phosphatidylserine decarboxylase 0.000
AMP-activated protein kinase 0.000
glutaryl-CoA dehydrogenase 0.000
alanyl-tRNA synthetase 0.000
PRPP synthetase 0.000
sulfhydryl oxidase 0.000
tryptophanyl-tRNA synthetase 0.000
phenylalanyl-tRNA synthetase 0.000
AMPK 0.000
biotinidase 0.000
succinyl-CoA synthetase 0.000
ornithine transcarbamylase 0.000
IscS 0.000
creatine kinase 0.000
branching enzyme 0.000
PDH 0.000
ATPase 0.000
glycerol kinase 0.000
succinic dehydrogenase 0.000
AMPK 0.000
TMT 0.000
MDH 0.000
MDH 0.000
PHD 0.000
LasR 0.000
ferrochelatase 0.000
chaperonin 0.000
PDK1 0.000
SCS 0.000
nucleotidase 0.000
ECH 0.000
21-hydroxylase 0.000
ribonucleotide reductase 0.000
alpha-ketoglutarate dehydrogenase 0.000
CPR 0.000
ribonucleotide reductase 0.000
purine nucleoside phosphorylase 0.000
pyruvate carboxylase 0.000
PNGase F 0.000
NQO1 0.000
glycerol-3-phosphate dehydrogenase 0.000
glutathione peroxidase 0.000
glycerol-3-phosphate dehydrogenase 0.000
MPP 0.000
TdT 0.000
superoxide dismutase 0.000
topoisomerase 0.000
TAT 0.000
topoisomerase 0.000
phosphoinositide 3-kinase 0.000
catalase 0.000
UDP-glucuronosyltransferase 0.000
enolase 0.000
xanthine oxidase 0.000
PCP 0.000
phosphofructokinase 0.000
NADPH-diaphorase 0.000
MMP 0.000
malate dehydrogenase 0.000
proteasome 0.000
transglutaminase 0.000
MIP 0.000
glutamine synthetase 0.000
adenosine deaminase 0.000
adenosine deaminase 0.000
aspartate aminotransferase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
ribonuclease 0.000
ribonuclease 0.000
alanine aminotransferase 0.000
thymidine kinase 0.000
DNase 0.000
reverse transcriptase 0.000
endonuclease 0.000
pepsin 0.000
protein kinase 0.000
gamma-glutamyl transpeptidase 0.000
transcriptase 0.000
luciferase 0.000
glutathione S-transferase 0.000
mitogen-activated protein kinase 0.000
lactate dehydrogenase 0.000
PARP 0.000
tyrosine hydroxylase 0.000
RNase 0.000
calcineurin 0.000
RNase 0.000
MEK 0.000
ACE 0.000
lipase 0.000
RNA polymerase 0.000
renin 0.000
ERK 0.000
alkaline phosphatase 0.000
Compound
DNA 0.000
coenzyme Q10 0.000
COX 0.000
CoQ 0.000
Coenzyme Q10 0.000
ATP 0.000
ubiquinone 0.000
reduced riboflavin 0.000
Cytochrome c 0.000
heme O 0.000
oxygen 0.000
AMPD 0.000
Deoxyuridine 0.000
4-oxobutanoic acid 0.000
NADH 0.000
leucine 0.000
phosphocreatine 0.000
3-methylcrotonyl-CoA 0.000
Triphosphate 0.000
CoQ9 0.000
BRA 0.000
Ferricyanide 0.000
Riboflavin 0.000
MGA 0.000
AICAR 0.000
4-hydroxyphenylpyruvate 0.000
NAD 0.000
NAD 0.000
Rotenone 0.000
AICAR 0.000
Riluzole 0.000
lysine 0.000
L-carnitine 0.000
folinic acid 0.000
Fumarate 0.000
Lactate 0.000
ubiquinol 0.000
nonanoic acid 0.000
ADP 0.000
Levetiracetam 0.000
iron 0.000
Acyl-CoA 0.000
MPT 0.000
Coenzyme A 0.000
nicotinamide 0.000
Rapamycin 0.000
dGMP 0.000
B17 0.000
carbamyl phosphate 0.000
decanoic acid 0.000
alanine 0.000
Clofibrate 0.000
Dec 0.000
decanoic acid 0.000
His 0.000
Kainic acid 0.000
Kainic acid 0.000
CIT 0.000
DAPT 0.000
FMN 0.000
CoA 0.000
Epigallocatechin 0.000
BSO 0.000
Guo 0.000
17-OHP 0.000
uridine 0.000
Linezolid 0.000
N-acetylaspartate 0.000
HCA 0.000
4-hydroxybenzoic acid 0.000
AAT 0.000
glucose 0.000
Enalapril 0.000
ADP 0.000
ADP 0.000
Wellcome 0.000
DPI 0.000
ammonium 0.000
PDH 0.000
Valproic acid 0.000
Taurine 0.000
Carnitine 0.000
nonyl 0.000
Clin 0.000
Guo 0.000
Thiamine 0.000
POP 0.000
phosphorus 0.000
arginine 0.000
nicotinic acid 0.000
nicotinic acid 0.000
FAD 0.000
nicotinic acid 0.000
Argentine 0.000
GSSG 0.000
DAMP 0.000
TCA 0.000
AZT 0.000
DES 0.000
SO3 0.000
pentose 0.000
pentose 0.000
serine 0.000
pentose 0.000
palmitoyl-CoA 0.000
CCP 0.000
Phosphatidylcholine 0.000
Biotin 0.000
pentose 0.000
2-nonenal 0.000
MPP 0.000
Lac 0.000
COI 0.000
MPP 0.000
tungsten 0.000
Vitamin E 0.000
2-oxoglutarate 0.000
Pyruvate 0.000
A 3 0.000
Gentamicin 0.000
nicotinic acid 0.000
Methionine 0.000
H2S 0.000
Phe 0.000
urea 0.000
FFA 0.000
UGA 0.000
threonine 0.000
CdCl2 0.000
Propofol 0.000
Glycogen 0.000
creatinine 0.000
acetyl-CoA 0.000
methyl methanesulfonate 0.000
phosphate 0.000
galactose 0.000
calcium 0.000
isoleucine 0.000
aspartic acid 0.000
isoleucine 0.000
aspartic acid 0.000
Retinal 0.000
Lactic acid 0.000
N-acetylcysteine 0.000
naphthoquinone 0.000
naphthoquinone 0.000
naphthoquinone 0.000
naphthoquinone 0.000
naphthoquinone 0.000
TTP 0.000
naphthoquinone 0.000
BLM 0.000
propionic acid 0.000
propionic acid 0.000
CIT 0.000
NADP 0.000
Neuronal 0.000
aspartic acid 0.000
methionine 0.000
naphthoquinone 0.000
more...