Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0751295 (memory loss)
3,619 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 203
amyloid precursor protein 182
MRI 152
Mol 127
acetylcholinesterase 116
CA1 92
amyloid beta 87
tau protein 68
brain-derived neurotrophic factor 66
She 63
APP 61
insulin 61
PS1 47
CSF 44
CA3 41
NMDA receptor 38
caspase-3 36
TNF 35
cytokine 34
olfactory 32
glial fibrillary acidic protein 31
CREB 31
CD4 30
apolipoprotein E 30
superoxide dismutase 28
Mem 27
GABA 27
synaptophysin 27
BACE1 26
presenilin 1 25
GSH 22
Bcl-2 22
axonal 21
tumor necrosis factor 21
endoplasmic reticulum 21
ATP 20
choline acetyltransferase 20
ERK 19
glutamate receptor 19
IL-6 19
ACS 19
GSK 18
nerve growth factor 18
AChE 17
inducible nitric oxide synthase 17
CD8 16
lipopolysaccharide 15
phosphodiesterase 14
butyrylcholinesterase 14
neurotrophin 14
APOE 14
catalase 14
AKT 14
muscarinic receptor 14
gut 14
Pol 13
histone 13
ROS 13
mTOR 13
prion protein 13
nicotinic acetylcholine receptor 13
IL-10 12
neurotrophic factor 12
DCX 12
amyloid protein 12
JNK 12
glutathione peroxidase 12
PSD-95 12
ubiquitin 12
AMP 11
NMR 11
BACE 11
SOD 11
Apolipoprotein E 11
PI3K 11
lymphoid 10
cAMP response element-binding protein 10
ERK1 10
cyclooxygenase-2 10
precursor protein 10
more...
Disease
Alzheimer's disease 1488
dementia 801
cognitive impairment 522
amnesia 257
depression 250
memory impairment 234
confusion 167
stroke 94
encephalitis 93
disorientation 89
epilepsy 84
cancer 83
diabetes 81
plaque 68
Parkinson's disease 66
psychosis 64
tumor 61
retrograde amnesia 60
hallucinations 56
forgetting 53
encephalopathy 53
HIV 53
hypertension 50
aphasia 48
ischemia 42
AIDS 37
coma 37
parkinsonism 34
temporal lobe epilepsy 34
brain atrophy 33
cognitive deficit 32
transient global amnesia 30
senile dementia 30
obesity 30
fits 29
anterograde amnesia 29
apraxia 28
immunodeficiency 28
aggression 26
multiple sclerosis 26
type 2 diabetes 25
schizophrenia 24
hydrocephalus 23
delirium 22
Down syndrome 22
GSH 22
delusions 21
lymphoma 21
Huntington's disease 20
incontinence 20
breast cancer 20
alcoholism 19
posttraumatic stress disorder 19
neuroblastoma 18
neurological disease 18
mental illness 18
major depressive disorder 17
cardiovascular disease 17
disinhibition 17
teratoma 16
malnutrition 16
brain disorder 16
vascular disease 16
systemic lupus erythematosus 16
peripheral neuropathy 16
herpes simplex 15
neuropathy 15
hemiparesis 15
amyloidosis 15
sleep disturbances 15
agnosia 14
cerebral ischemia 14
migraine 14
status epilepticus 13
bipolar disorder 13
Korsakoff's syndrome 13
sleep disorders 13
nystagmus 13
Vascular dementia 12
fugue 12
more...
Symptom
memory loss 3619
seizures 193
headache 126
fatigue 93
weakness 64
ataxia 55
pain 46
dizziness 45
insomnia 42
agitation 35
tremor 33
nausea 30
apathy 27
forgetfulness 26
anesthesia 25
sleepiness 24
vomiting 23
diarrhea 22
personality change 19
dysarthria 17
myoclonus 16
anorexia 15
arthralgia 15
numbness 15
vertigo 15
bradykinesia 14
paresthesia 14
cerebellar ataxia 12
abdominal pain 12
stigma 12
myalgia 12
blurred vision 11
incoordination 11
hypothermia 10
lethargy 10
blackout 10
discomfort 9
discomfort 9
hot flashes 7
tinnitus 7
paresis 7
tingling 7
functional recovery 6
chest pain 6
exhaustion 6
dystonia 6
shortness of breath 6
ophthalmoplegia 6
ataxic gait 6
cough 6
catatonia 5
consciousness disturbance 5
thinning 5
hemiplegia 5
chorea 5
polyuria 5
Ill 4
nausea and vomiting 4
dyspnea 4
polydipsia 4
paraparesis 4
rhinorrhea 4
respiratory distress 4
clumsiness 4
hypersomnia 4
intention tremor 4
analgesia 4
hypertonia 4
Sedation 3
abnormal gait 3
acute stress 3
spasm 3
night sweats 3
syncope 3
clonus 3
constipation 3
pallor 3
asthenia 3
tonic-clonic seizure 3
back pain 3
more...
Drug
CSF 44
ROS 13
vitamin E 12
Scopolamine 9
Donepezil 8
Phenytoin 6
p75 5
Estrogens 5
lysine 5
Piracetam 5
ascorbate 4
Leaf 4
Cardiovasc 4
EE2 4
Vitamin B 3
Parkin 3
Glucagon 3
Spectrum 3
IL-2 3
nitroglycerin 3
NADH 3
TAT 3
Parkin 3
Ginseng 3
niacin 2
MAP 2
Ethanol 2
Exelon 2
PCP 2
Nitric Oxide 2
PMPA 2
Nephron 2
caffeine 2
Aricept 2
IFN-gamma 2
ABC 2
Monit 2
ROC 2
Zileuton 1
Anafranil 1
Rauwolfia serpentina 1
ZnCl2 1
Alanine 1
lactose 1
Sorafenib 1
Campath 1
Campath 1
DEX 1
MCZ 1
MCZ 1
Ipilimumab 1
Hypaque 1
ampicillin 1
ZnCl2 1
DDAVP 1
ULR 1
CDP 1
Etoposide 1
CFS 1
MEA 1
Rolipram 1
Indomethacin 1
Cibacron Blue 1
DMAA 1
Vinpocetine 1
Nexavar 1
Riboflavin 1
Red ginseng 1
Vitamin K2 1
Rutin 1
Cobalamin 1
Propofol 1
Atenolol 1
ENT 1
Reminyl 1
FAD 1
Domoic Acid 1
Adenosine Monophosphate 1
Iopamidol 1
PCB 1
more...
Enzyme
acetylcholinesterase 136
cholinesterase 50
protein kinase 42
superoxide dismutase 37
mitogen-activated protein kinase 35
caspase-3 27
ERK 24
choline acetyltransferase 20
GSK 19
ACS 19
catalase 18
phosphodiesterase 14
protein kinase C 14
glutathione peroxidase 13
monoamine oxidase 11
calcineurin 9
proteasome 9
AMP-activated protein kinase 9
AMPK 8
AMPK 8
CaMKII 8
CD10 8
peroxidase 7
glutathione reductase 6
beta-secretase 6
NOS 6
ATPase 5
cytochrome oxidase 5
prolyl endopeptidase 5
adenylate cyclase 4
alanine aminotransferase 4
insulin-degrading enzyme 4
caspase-9 4
alkaline phosphatase 4
heme oxygenase 3
luciferase 3
cathepsin B 3
glutathione S-transferase 3
caspase-8 3
focal adhesion kinase 3
caspase-1 3
ceruloplasmin 3
TAT 3
aspartate aminotransferase 3
MEK 3
protein phosphatase 2A 3
cdc2 2
endothelin-converting enzyme 2
alcohol dehydrogenase 2
RNase 2
MAP 2
NQO1 2
5'-nucleotidase 2
lysozyme 2
aldehyde dehydrogenase 2
phosphoinositide 3-kinase 2
soluble epoxide hydrolase 2
PARP 2
PCP 2
phospholipase C 2
PDE 2
IKK 2
NO synthase 2
prostate-specific membrane antigen 2
3-hydroxy-3-methylglutaryl coenzyme A reductase 2
creatine kinase 2
diaphorase 2
sulfatase 2
endonuclease 2
enolase 2
RNase 2
dihydrolipoamide succinyltransferase 1
pepsin 1
caspase-2 1
methylmalonyl-CoA mutase 1
MEKK1 1
3-hydroxy-3-methylglutaryl-CoA reductase 1
NADPH oxidase 1
carbonic anhydrase 1
P-glycoprotein 1
more...
Compound
water 229
Dec 222
Clin 150
calcium 93
oxygen 89
DNA 76
glucose 74
glutamate 68
His 38
TNF 35
nitric oxide 35
ethanol 34
NMDA 34
sodium 28
GABA 28
AMPA 28
GABA 27
GSH 22
GSH 22
ATP 20
cAMP 20
ACS 19
ACS 19
potassium 19
hydrogen 18
zinc 17
galactose 17
mercury 17
Neuronal 17
methionine 16
5-HT 16
arginine 14
iron 14
DSM 13
CO2 12
Domoic acid 12
copper 11
aluminum 11
homocysteine 11
phosphate 11
AMP 11
tryptophan 11
tyrosine 10
tryptophan 10
tryptophan 10
Cereb 10
Insulin 10
nicotinamide 10
tryptophan 10
gamma-aminobutyric acid 10
leucine 10
STZ 9
SEE 9
glutamine 9
nitrogen 9
noradrenaline 9
creatinine 8
serine 8
Estrogen 8
Estrogen 8
Resveratrol 8
bromide 8
MTT 8
ACh 8
Asp 8
urea 7
MDA 7
aspartic acid 7
aspartic acid 7
Memantine 7
vitamin D 7
Melatonin 7
iodine 7
methanol 7
ADP 6
aspartic acid 6
valine 6
salt 6
threonine 6
Glutamate 6
more...