Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0751295 (
memory loss
)
3,619
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
203
amyloid precursor protein
182
MRI
152
Mol
127
acetylcholinesterase
116
CA1
92
amyloid beta
87
tau protein
68
brain-derived neurotrophic factor
66
She
63
APP
61
insulin
61
PS1
47
CSF
44
CA3
41
NMDA receptor
38
caspase-3
36
TNF
35
cytokine
34
olfactory
32
glial fibrillary acidic protein
31
CREB
31
CD4
30
apolipoprotein E
30
superoxide dismutase
28
Mem
27
GABA
27
synaptophysin
27
BACE1
26
presenilin 1
25
GSH
22
Bcl-2
22
axonal
21
tumor necrosis factor
21
endoplasmic reticulum
21
ATP
20
choline acetyltransferase
20
ERK
19
glutamate receptor
19
IL-6
19
ACS
19
GSK
18
nerve growth factor
18
AChE
17
inducible nitric oxide synthase
17
CD8
16
lipopolysaccharide
15
phosphodiesterase
14
butyrylcholinesterase
14
neurotrophin
14
APOE
14
catalase
14
AKT
14
muscarinic receptor
14
gut
14
Pol
13
histone
13
ROS
13
mTOR
13
prion protein
13
nicotinic acetylcholine receptor
13
IL-10
12
neurotrophic factor
12
DCX
12
amyloid protein
12
JNK
12
glutathione peroxidase
12
PSD-95
12
ubiquitin
12
AMP
11
NMR
11
BACE
11
SOD
11
Apolipoprotein E
11
PI3K
11
lymphoid
10
cAMP response element-binding protein
10
ERK1
10
cyclooxygenase-2
10
precursor protein
10
more...
Disease
Alzheimer's disease
1488
dementia
801
cognitive impairment
522
amnesia
257
depression
250
memory impairment
234
confusion
167
stroke
94
encephalitis
93
disorientation
89
epilepsy
84
cancer
83
diabetes
81
plaque
68
Parkinson's disease
66
psychosis
64
tumor
61
retrograde amnesia
60
hallucinations
56
forgetting
53
encephalopathy
53
HIV
53
hypertension
50
aphasia
48
ischemia
42
AIDS
37
coma
37
parkinsonism
34
temporal lobe epilepsy
34
brain atrophy
33
cognitive deficit
32
transient global amnesia
30
senile dementia
30
obesity
30
fits
29
anterograde amnesia
29
apraxia
28
immunodeficiency
28
aggression
26
multiple sclerosis
26
type 2 diabetes
25
schizophrenia
24
hydrocephalus
23
delirium
22
Down syndrome
22
GSH
22
delusions
21
lymphoma
21
Huntington's disease
20
incontinence
20
breast cancer
20
alcoholism
19
posttraumatic stress disorder
19
neuroblastoma
18
neurological disease
18
mental illness
18
major depressive disorder
17
cardiovascular disease
17
disinhibition
17
teratoma
16
malnutrition
16
brain disorder
16
vascular disease
16
systemic lupus erythematosus
16
peripheral neuropathy
16
herpes simplex
15
neuropathy
15
hemiparesis
15
amyloidosis
15
sleep disturbances
15
agnosia
14
cerebral ischemia
14
migraine
14
status epilepticus
13
bipolar disorder
13
Korsakoff's syndrome
13
sleep disorders
13
nystagmus
13
Vascular dementia
12
fugue
12
more...
Symptom
memory loss
3619
seizures
193
headache
126
fatigue
93
weakness
64
ataxia
55
pain
46
dizziness
45
insomnia
42
agitation
35
tremor
33
nausea
30
apathy
27
forgetfulness
26
anesthesia
25
sleepiness
24
vomiting
23
diarrhea
22
personality change
19
dysarthria
17
myoclonus
16
anorexia
15
arthralgia
15
numbness
15
vertigo
15
bradykinesia
14
paresthesia
14
cerebellar ataxia
12
abdominal pain
12
stigma
12
myalgia
12
blurred vision
11
incoordination
11
hypothermia
10
lethargy
10
blackout
10
discomfort
9
discomfort
9
hot flashes
7
tinnitus
7
paresis
7
tingling
7
functional recovery
6
chest pain
6
exhaustion
6
dystonia
6
shortness of breath
6
ophthalmoplegia
6
ataxic gait
6
cough
6
catatonia
5
consciousness disturbance
5
thinning
5
hemiplegia
5
chorea
5
polyuria
5
Ill
4
nausea and vomiting
4
dyspnea
4
polydipsia
4
paraparesis
4
rhinorrhea
4
respiratory distress
4
clumsiness
4
hypersomnia
4
intention tremor
4
analgesia
4
hypertonia
4
Sedation
3
abnormal gait
3
acute stress
3
spasm
3
night sweats
3
syncope
3
clonus
3
constipation
3
pallor
3
asthenia
3
tonic-clonic seizure
3
back pain
3
more...
Drug
CSF
44
ROS
13
vitamin E
12
Scopolamine
9
Donepezil
8
Phenytoin
6
p75
5
Estrogens
5
lysine
5
Piracetam
5
ascorbate
4
Leaf
4
Cardiovasc
4
EE2
4
Vitamin B
3
Parkin
3
Glucagon
3
Spectrum
3
IL-2
3
nitroglycerin
3
NADH
3
TAT
3
Parkin
3
Ginseng
3
niacin
2
MAP
2
Ethanol
2
Exelon
2
PCP
2
Nitric Oxide
2
PMPA
2
Nephron
2
caffeine
2
Aricept
2
IFN-gamma
2
ABC
2
Monit
2
ROC
2
Zileuton
1
Anafranil
1
Rauwolfia serpentina
1
ZnCl2
1
Alanine
1
lactose
1
Sorafenib
1
Campath
1
Campath
1
DEX
1
MCZ
1
MCZ
1
Ipilimumab
1
Hypaque
1
ampicillin
1
ZnCl2
1
DDAVP
1
ULR
1
CDP
1
Etoposide
1
CFS
1
MEA
1
Rolipram
1
Indomethacin
1
Cibacron Blue
1
DMAA
1
Vinpocetine
1
Nexavar
1
Riboflavin
1
Red ginseng
1
Vitamin K2
1
Rutin
1
Cobalamin
1
Propofol
1
Atenolol
1
ENT
1
Reminyl
1
FAD
1
Domoic Acid
1
Adenosine Monophosphate
1
Iopamidol
1
PCB
1
more...
Enzyme
acetylcholinesterase
136
cholinesterase
50
protein kinase
42
superoxide dismutase
37
mitogen-activated protein kinase
35
caspase-3
27
ERK
24
choline acetyltransferase
20
GSK
19
ACS
19
catalase
18
phosphodiesterase
14
protein kinase C
14
glutathione peroxidase
13
monoamine oxidase
11
calcineurin
9
proteasome
9
AMP-activated protein kinase
9
AMPK
8
AMPK
8
CaMKII
8
CD10
8
peroxidase
7
glutathione reductase
6
beta-secretase
6
NOS
6
ATPase
5
cytochrome oxidase
5
prolyl endopeptidase
5
adenylate cyclase
4
alanine aminotransferase
4
insulin-degrading enzyme
4
caspase-9
4
alkaline phosphatase
4
heme oxygenase
3
luciferase
3
cathepsin B
3
glutathione S-transferase
3
caspase-8
3
focal adhesion kinase
3
caspase-1
3
ceruloplasmin
3
TAT
3
aspartate aminotransferase
3
MEK
3
protein phosphatase 2A
3
cdc2
2
endothelin-converting enzyme
2
alcohol dehydrogenase
2
RNase
2
MAP
2
NQO1
2
5'-nucleotidase
2
lysozyme
2
aldehyde dehydrogenase
2
phosphoinositide 3-kinase
2
soluble epoxide hydrolase
2
PARP
2
PCP
2
phospholipase C
2
PDE
2
IKK
2
NO synthase
2
prostate-specific membrane antigen
2
3-hydroxy-3-methylglutaryl coenzyme A reductase
2
creatine kinase
2
diaphorase
2
sulfatase
2
endonuclease
2
enolase
2
RNase
2
dihydrolipoamide succinyltransferase
1
pepsin
1
caspase-2
1
methylmalonyl-CoA mutase
1
MEKK1
1
3-hydroxy-3-methylglutaryl-CoA reductase
1
NADPH oxidase
1
carbonic anhydrase
1
P-glycoprotein
1
more...
Compound
water
229
Dec
222
Clin
150
calcium
93
oxygen
89
DNA
76
glucose
74
glutamate
68
His
38
TNF
35
nitric oxide
35
ethanol
34
NMDA
34
sodium
28
GABA
28
AMPA
28
GABA
27
GSH
22
GSH
22
ATP
20
cAMP
20
ACS
19
ACS
19
potassium
19
hydrogen
18
zinc
17
galactose
17
mercury
17
Neuronal
17
methionine
16
5-HT
16
arginine
14
iron
14
DSM
13
CO2
12
Domoic acid
12
copper
11
aluminum
11
homocysteine
11
phosphate
11
AMP
11
tryptophan
11
tyrosine
10
tryptophan
10
tryptophan
10
Cereb
10
Insulin
10
nicotinamide
10
tryptophan
10
gamma-aminobutyric acid
10
leucine
10
STZ
9
SEE
9
glutamine
9
nitrogen
9
noradrenaline
9
creatinine
8
serine
8
Estrogen
8
Estrogen
8
Resveratrol
8
bromide
8
MTT
8
ACh
8
Asp
8
urea
7
MDA
7
aspartic acid
7
aspartic acid
7
Memantine
7
vitamin D
7
Melatonin
7
iodine
7
methanol
7
ADP
6
aspartic acid
6
valine
6
salt
6
threonine
6
Glutamate
6
more...