Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0751295 (memory loss)
 3,619 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case is presented of a 38-year old woman who, when treated for alternating amenorrhea and menorrhagia with Lyndiol (.l5 mg mestranol and 5 mg lynestrenol, combined) became anxious and depressed and developed depigmentation and alopecia of her left eyebrow. She showed several symptoms of luteal insufficiency: menstrual disorders, spontaneous abortions, menometrorrhagia, and hyperplastic endometrium, a fter progestagen treatment. During a 6 month course of Lydiol she became severely depressed with short attention span, loss of memory, fatique, frigidity, obsessions and phobic behavior. Treatment with Antideprein (Tofranil) and Napoton (Librium) were not effective, but stopping Lyndiol improved the depression, frigidity, and partially improved the obsessive-phobic behavior. The disscussion centered on the role of monoamines in the depressions associated with oral contraceptives.
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PMID:[Syndrome of depression and depigmentation after administration of combined estrogen-progestagens]. 1225 82