Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0740577 (acute abdominal pain)
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Human Gene/Protein
Ras-related protein Rab-7b 12.0
coagulation factor I 11.2
BCA1 10.5
NKX2-8 10.1
HMBS 9.0
HOXC9 8.8
HOXD9 8.5
beta globin chain 8.3
IER3 8.1
SERPINH1 7.8
SAA protein 7.5
IL6ST 7.4
variegate porphyria 7.1
I-FABP 7.0
KvLQT1 6.9
beta catenin 6.8
porphobilinogen deaminase 6.7
thyroid transcription factor-1 6.4
API2 6.4
A27 6.2
INSR 6.1
ID3 6.1
cytokeratin 7 6.0
KLF5 6.0
TNFRSF1A 6.0
homeobox transcription factor 6.0
SOX4 5.9
macrophage-derived chemokine 5.7
Sho 5.7
PBG 5.7
CN2 5.6
ALK1 5.5
amylase 5.5
CA-125 5.5
AMACR 5.5
AMT 5.5
platelet-derived growth factor receptor alpha 5.4
Rubinstein-Taybi syndrome 5.4
white cell 5.4
HES1 5.3
BCL-6 5.3
CK20 5.3
mast cell tryptase 5.2
inhibin alpha 5.1
PRISM 5.1
She 5.1
ASAT 5.1
period 3 5.1
MALT1 5.0
MEFV 4.9
pancreatic lipase 4.8
BTR 4.8
CD117 4.8
lipase 4.8
LCA 4.8
WASP 4.8
high mobility group box 4.7
AIP 4.7
SS-B 4.6
MIS 4.6
signal transducer and activator of transcription 1 4.6
carbonic anhydrase IX 4.6
CAB 4.6
Lipase 4.6
CCL22 4.5
MCL 4.5
leukocyte common antigen 4.4
SS-A 4.4
slim 4.4
prune 4.4
C1 inhibitor 4.2
HCG 4.2
MTB 4.1
muscle specific 4.1
CXCL13 4.1
CCL17 4.1
glutamate pyruvate transaminase 4.0
anaplastic lymphoma kinase 4.0
cocaine- and amphetamine-regulated transcript 4.0
alpha2-macroglobulin 4.0
ADAMTS13 4.0
EWS 4.0
LAP 4.0
RANTES) 3.9
placental alkaline phosphatase 3.9
RIF 3.8
EMA 3.8
PDGFRA 3.7
APS 3.7
CD10 3.7
PCT 3.7
CRL 3.6
LPL 3.6
UGT1A1 3.6
PTA 3.6
CD43 3.6
KIT 3.6
C-reactive protein 3.6
patched 3.5
CD30 3.5
AAS 3.4
SAP 3.4
COL1A1 3.4
AE3 3.3
alpha-1-antitrypsin 3.3
glutathione transferase 3.3
CK7 3.3
ACG 3.2
CTLA4 3.2
IBD 3.2
fatty acid binding protein 3.2
factor V Leiden 3.2
CMS 3.2
smooth muscle actin 3.1
CRP 3.1
platelet-derived growth factor receptor 3.0
high mobility group box 1 3.0
serum amyloid A 3.0
ornithine transcarbamylase 3.0
DIC 3.0
deoxyribonuclease 2.9
ara 2.9
PEP 2.9
c-kit 2.9
SAGE 2.9
CD1a 2.9
ALA 2.8
Factor VIII 2.8
twist 2.7
AE1 2.7
MTS 2.7
ABCG2 2.7
MRI 2.7
reserved 2.7
alpha-fetoprotein 2.7
alpha-amylase 2.7
parathyroid hormone-related protein 2.7
E.coli 2.6
rheumatoid factor 2.6
ALK 2.6
CRF 2.6
carcinoembryonic antigen 2.5
tie 2.5
CTP 2.4
HCC 2.4
chromogranin A 2.4
CAT 2.4
S100 2.4
AFP 2.4
factor VII 2.4
PDF 2.4
protein C 2.3
calretinin 2.3
lipoprotein lipase 2.3
IVF 2.3
chorionic gonadotropin 2.3
CD34 2.3
urokinase-type plasminogen activator 2.3
alpha-smooth muscle actin 2.2
desmin 2.2
more...
Disease
stage IV mesothelioma 14.0
Spontaneous rupture of bladder 14.0
Acute mesenteric arterial occlusion 14.0
Corpus luteum cyst 13.0
Basal pneumonia 13.0
Right-sided colitis 13.0
drepanocytic anemia 13.0
Adrenal infarction 12.7
Mesenteric vasculitis 12.6
Omental infarction 12.5
Epiploic appendagitis 12.4
left sided appendicitis 12.4
Ovarian hemorrhage 12.4
Infective aortitis 12.4
Omental torsion 12.3
fimbrial cyst 12.0
Tubal abortion 12.0
Superior mesenteric vein thrombosis 11.3
Spontaneous rupture of spleen 11.2
Biliary ascariasis 11.2
Ovarian fibroma 10.8
Varicella-zoster virus infection 10.8
Myoglobinemia 10.5
Neutropenic colitis 10.4
Inflammatory abdominal aortic aneurysm 10.4
Right atrial myxoma 10.3
Edematous pancreatitis 10.2
Wandering spleen 10.1
Acute gastric volvulus 10.1
Non-occlusive mesenteric ischemia 10.0
Recurrent pyogenic cholangitis 10.0
Norwalk gastroenteritis 9.9
Abdominal lymphadenopathy 9.9
acute appendicitis 9.8
Afferent loop syndrome 9.8
mesenteric lymphadenitis 9.8
Sigmoid colon 9.8
Sigmoid colon 9.8
Intra-abdominal hemorrhage 9.7
Internal hernia 9.7
myometritis 9.7
appendicitis 9.6
AIDS cholangiopathy 9.6
Renal infarction 9.4
Bilateral hydronephrosis 9.4
Biloma 9.4
splenic infarction 9.4
Bowel perforation 9.3
Type V hyperlipoproteinemia 9.3
Primary Sjogren's syndrome 9.2
Ovarian pregnancy 9.2
lithopedion 9.2
Clostridium septicum infection 9.2
Disseminated coccidioidomycosis 9.2
Zieve's syndrome 9.2
mesenteric thrombosis 9.1
Mesenteric panniculitis 9.1
periappendicitis 9.1
Adrenal hemorrhage 9.1
Small bowel obstruction 9.1
colonic diverticulitis 9.0
Splenic artery aneurysm 9.0
Intestinal infarction 8.9
enterolith 8.9
metastatic Wilms' tumor 8.8
gallbladder empyema 8.8
Ruptured abdominal aortic aneurysm 8.8
diverticulitis 8.8
panaritium 8.8
Duodenal perforation 8.8
Reactive hypoglycemia 8.8
Uterine rupture 8.7
cholangiolitis 8.7
Acute mesenteric ischemia 8.7
Sclerosing mesenteritis 8.7
gynecologic neoplasm 8.7
clotting factor deficiency 8.7
perforated duodenal ulcer 8.6
Angiostrongylus costaricensis 8.5
Pneumatosis intestinalis 8.5
Aortocaval fistula 8.4
acute intermittent porphyria 8.4
Acalculous cholecystitis 8.4
Pancreatic necrosis 8.4
trichobezoar 8.4
Erosive gastritis 8.4
Meckel's diverticulum 8.3
Meckel's diverticulum 8.3
Gastric perforation 8.3
Abdominal compartment syndrome 8.3
Degos 8.3
benign ovarian cyst 8.3
Mesenteric fibromatosis 8.2
Pneumoperitoneum 8.1
Abdominal actinomycosis 8.1
Intestinal pseudo-obstruction 8.1
Pancreatic pseudocyst 8.1
Lymphoid hyperplasia 8.1
Acute acalculous cholecystitis 8.1
pelvic adhesions 8.1
biliary colic 8.0
hematometra 8.0
Enteropathy-associated T-cell lymphoma 8.0
pylephlebitis 8.0
adrenal neoplasm 8.0
Abdominal pregnancy 8.0
Intestinal ischemia 8.0
ureterolithiasis 8.0
SLE flare 7.9
acute gastritis 7.9
Uterine perforation 7.9
Potomac horse fever 7.9
abdominal migraine 7.9
Ovarian metastasis 7.9
GI perforation 7.8
acute thyroiditis 7.8
cholecystitis 7.8
Congenital afibrinogenemia 7.8
intussusception 7.8
marginal ulcer 7.8
Mesenchymal hamartoma 7.8
anterolateral myocardial infarction 7.8
acute cholecystitis 7.8
volvulus 7.8
bowel obstruction 7.8
paralytic ileus 7.7
ischemic colitis 7.7
Placenta percreta 7.7
sickle cell crisis 7.7
hepatic porphyria 7.6
bezoar 7.6
Toxocara canis infection 7.6
Campylobacter enteritis 7.6
Ectopic pancreas 7.5
tubal pregnancy 7.5
hydrosalpinx 7.5
Congo hemorrhagic fever 7.5
Emphysematous cystitis 7.5
pyometra 7.5
coproporphyria 7.5
phytobezoar 7.5
Hyperamylasemia 7.4
splenic disease 7.4
strangulated hernia 7.4
porphyria 7.4
ovarian cysts 7.3
Munchausen syndrome 7.3
Solid pseudopapillary tumor 7.3
Bornholm 7.3
acute endocarditis 7.3
Endometrioma 7.3
clostridial infection 7.3
infectious enteritis 7.2
acute salpingitis 7.2
jejunitis 7.2
Libman-Sacks endocarditis 7.1
myoma 7.1
muscle swelling 7.1
Pneumatosis cystoides intestinalis 7.1
Yolk sac tumor 7.0
more...
Symptom
acute abdominal pain 14.0
Rebound tenderness 12.2
localized abdominal pain 11.1
Kehr's sign 10.7
decreased bowel sounds 10.5
left lower quadrant pain 10.1
generalized abdominal pain 10.0
acute abdomen 9.7
Lower abdominal pain 9.4
right lower quadrant pain 9.4
Pneumobilia 9.3
iliac fossa pain 9.3
McBurney's point 9.2
Murphy's sign 9.0
abdominal rigidity 9.0
Acute chest pain 8.4
abdominal pain 7.8
right upper quadrant pain 7.7
Gastrointestinal symptoms 7.4
renal colic 7.3
left upper quadrant pain 6.9
colic 6.6
Flare 6.5
chyluria 6.4
generalized pain 6.3
vomiting 6.3
dyschezia 6.2
inanition 6.2
epigastric pain 6.0
abdominal discomfort 6.0
constipation 5.9
pelvic pain 5.9
ketonuria 5.9
dark urine 5.8
hyperemesis 5.7
acute pain 5.7
loin pain 5.6
Physical findings 5.6
nausea and vomiting 5.5
testicular pain 5.5
oliguria 5.4
Tenderness 5.4
intestinal bleeding 5.3
abdominal fullness 5.3
nausea 5.2
tenesmus 5.1
abdominal cramps 4.9
flank pain 4.9
retching 4.9
hypoproteinemia 4.8
pleuritic chest pain 4.8
dysuria 4.7
pallor 4.7
sneezing 4.7
chronic constipation 4.6
Sedation 4.6
anorexia 4.5
splenomegaly 4.3
bloating 4.3
Wind 4.2
diarrhea 4.2
sore throat 4.1
leg pain 4.0
fever of unknown origin 3.9
Postoperative pain 3.9
polydipsia 3.9
productive cough 3.8
lethargy 3.8
night sweats 3.7
chills 3.5
pain 3.5
cancer pain 3.4
syncope 3.4
chest pain 3.4
photophobia 3.3
enuresis 3.3
shortness of breath 3.2
neuralgia 3.2
respiratory distress 3.2
hepatomegaly 3.1
cough 3.0
hemiplegia 3.0
chorea 2.9
myalgia 2.9
hepatosplenomegaly 2.9
rhinorrhea 2.8
dyspnea 2.8
analgesia 2.8
arthralgia 2.7
back pain 2.7
spasm 2.7
tachypnea 2.7
sleepiness 2.7
asthenia 2.6
Ill 2.5
polyuria 2.4
hemoptysis 2.4
collapse 2.3
flushing 2.3
discomfort 2.3
dizziness 2.3
headache 2.3
low back pain 2.3
ophthalmoplegia 2.3
weakness 2.2
discomfort 2.2
myoclonus 1.9
acute stress 1.8
paresthesia 1.7
insomnia 1.6
cachexia 1.5
hypotonia 1.5
vertigo 1.2
anesthesia 1.1
hypercapnia 1.0
regurgitation 1.0
fatigue 0.9
seizures 0.9
angina 0.6
thinning 0.5
erythema 0.3
acidity 0.1
overweight -0.7
Drug
Demerol 7.9
Human Serum Albumin 7.7
Kayexalate 7.7
Mesalazine 6.1
Spiegel 6.1
Magnevist 6.0
Iohexol 6.0
Gastro 5.7
Duloxetine 5.7
Pemetrexed 5.3
Ipilimumab 5.3
Tocilizumab 5.2
Papaverine 5.1
Vicryl 4.9
Domperidone 4.6
HCG 4.2
Methylprednisolone 4.1
DDAVP 4.1
DDAVP 4.0
Acyclovir 3.9
Etoposide 3.8
ALA 3.5
Glycyrrhiza 3.5
Bayer 3.3
Norplant 3.2
Estrogens 2.8
Rituximab 2.5
EE2 2.0
Spectrum 2.0
Portal 1.9
ENT 1.9
ROC 1.1
ampicillin 0.9
Asn 0.5
Monit -0.1
Cardiovasc -0.3
Leaf -0.4
Dial -0.9
CSF -0.9
Dermatol -1.2
Enzyme
isoamylase 7.0
porphobilinogen deaminase 6.2
uroporphyrinogen decarboxylase 5.1
lipase 4.7
LPL 3.6
tryptase 3.5
deoxyribonuclease 3.4
deoxyribonuclease 3.4
PTA 3.2
alpha-amylase 3.2
glucoamylase 2.9
BMT 2.6
asparaginase 2.6
CD10 2.3
lipoprotein lipase 2.2
urokinase-type plasminogen activator 2.2
CAD 1.9
CAD 1.9
alanine aminotransferase 1.9
plasmin 1.8
CAD 1.8
alkaline phosphatase 1.7
transglutaminase 1.7
pyruvate kinase 1.6
ACE 1.4
phospholipase A2 1.2
aspartate aminotransferase 1.2
urease 1.1
lactate dehydrogenase 1.1
urease 1.1
DNase 1.1
APC 1.0
gamma-glutamyl transpeptidase 0.8
tissue plasminogen activator 0.5
thromboplastin 0.3
beta-lactamase 0.3
ERK 0.2
calcineurin -0.1
catalase -0.2
creatine kinase -0.2
trypsin -0.4
glutathione S-transferase -0.5
thrombin -1.1
renin -1.2
focal adhesion kinase -1.5
Compound
Phenazocine 14.0
Dolin 8.8
A-14 8.5
BON 6.9
C 5 6.9
Florid 6.8
Alfentanil 6.1
DBI 6.1
PBG 6.0
BEP 5.7
Meperidine 5.6
Papaverine 5.1
Fenofibrate 4.7
Tramadol 4.5
Hemin 4.5
A 42 4.5
Methylprednisolone 4.3
hippurate 4.0
Acyclovir 4.0
Valproic acid 4.0
Coronal 3.8
barium 3.7
Warfarin 3.6
ANCA 3.1
APS 2.9
A 71 2.9
Isoproterenol 2.8
PEP 2.8
DIC 2.6
MTS 2.6
Formal 2.5
BLM 2.5
CAT 2.4
CAT 2.4
CTP 2.4
Guo 2.4
A 1 2.3
VP-16 2.3
CAT 2.3
CAP 2.3
Lead 2.3
Metformin 2.3
Valproic acid 2.2
Metformin 2.2
INH 2.2
creatinine 2.2
5-FU 2.2
Tamoxifen 2.1
L-carnitine 2.1
A 3 2.1
His 2.0
Salix 2.0
Cocaine 1.9
EMS 1.9
Guo 1.7
Estrogen 1.6
pyrrolidine 1.5
pyrrolidine 1.5
Hemoglobin 1.2
DDP 1.1
Diabetol 1.0
Adrenal 0.9
Angiotensin II 0.9
Estrogen 0.7
Cholesterol 0.7
oxalate 0.7
Clin 0.6
Diabetol 0.6
sodium chloride 0.5
tin 0.4
uridine 0.3
Dec 0.2
valine 0.1
carbonate 0.1
glutamic acid -0.0
Optimal -0.1
glucose -0.4
iodine -0.6
EDTA -0.7
EDTA -0.7
mercury -0.8
iron -0.8
CO2 -0.9
Dial -1.0
urea -1.0
Asp -1.1
sodium -1.5
potassium -1.6
Phe -1.7
nitrate -1.7
calcium -1.8
acetate -1.9
TNF -1.9
alanine -2.1
oxygen -2.2
galactose -2.2
cysteine -2.2
water -2.3
lysine -2.4
copper -2.5
arginine -2.6
sulfate -2.8
ATP -3.0
DNA -3.7
Cardiol -3.9