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Query: UMLS:C0740577 (acute abdominal pain)
 1,982 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Colonic metastasis from lung cancer is rare and generally asymptomatic. Here, we report a case with lung adenocarcinoma that presented with acute abdominal pain due to intestinal obstruction caused by the metastatic colon tumor. The patient underwent emergency colonoscopy and the pathologic report was adenocarcinoma, which was the same as that for a bronchoscopic biopsy from a large lung mass. Immunohistochemistry was positive for thyroid transcription factor-1 and cytokeratin 7, and negative for cytokeratin 20 and caudal-related homeobox transcription factor 2 on both lung biopsy and colon surgical specimens. Accordingly, we used immunohistochemistry for thyroid transcription factor-1, cytokeratin 7, cytokeratin 20 and caudal-related homeobox transcription factor-2 to diagnose primary adenocarcinoma of the lung with colonic metastasis.
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PMID:Colonic metastasis from a primary adenocarcinoma of the lung presenting with acute abdominal pain: a case report. 2004 Apr 72

We report on 2 cases of visceral arterial embolism presenting with acute abdominal pain. In neither patient a cause could be established on initial clinical, laboratory, echographic or radiological investigation. Both patients were subsequently found to have a mural thrombus in the thoracic aorta, with visceral arterial embolism. Each underwent a successful operative thrombectomy. Both patients had a normal underlying aortic intima at inspection. The first patient was a young male with no known diseases. He regularly used cannabis and tested positive on admission, an association not yet reported with aortic mural thrombus. He was found to have a slightly reduced protein C. The second patient was a middle aged man with non-insulin dependent diabetes, hyperlipidaemia, arterial hypertension and hyperthyroidism. He was found to have an underlying adenocarcinoma of the lung and received chemotherapy. He died due to his cancer, 4 months after first presentation.
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PMID:An uncommon cause of visceral arterial embolism in patients presenting with acute abdominal pain: a report of 2 cases. 2045 52

Symptomatic gastro-intestinal metastasis in lung cancer is extremely rare and only a few case reports have been published. Here, we report a case with lung adenocarcinoma that presented with acute abdominal pain, nausea and vomiting due to duodenum, jejunum, and colon obstruction by the gastro-intestinal metastasis. The patient underwent colonoscopy and the pathologic report was adenocarcinoma. When there are similar histologic findings in both colon and pulmonary lesion, the question is whether both lesions are primary cancer or the colon lesions are metastases from lung cancer. Microscopic examination of a conventional pathologic section was not sufficient to make this determination. Immunohistochemistry was positive for thyroid transcription factor-1 (TTF-1) and cytokeratin 7 (CK7), and negative for cytokeratin 20 (CK20) and caudal-related homeobox transcription factor-2 (CDX-2) on colon mucosa specimen. Accordingly, we used immunohistochemical marker for differential diagnosis of primary adenocarcinoma of the lung with gastro-intestinal metastasis.
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PMID:[Gastrointestinal metastasis from a primary adenocarcinoma of the lung presenting with acute abdominal pain]. 2261 34

Small intestinal metastasis from primary lung carcinoma is infrequent and seen at the terminal stage of the disease as the first sign. These patients are often present as perforation and peritonitis but rarely with small bowel obstruction. We reported a case of a 61-year-old man who was admitted to our hospital with acute abdominal pain. Abdominal X-ray manifested an acute ileus. Ileoileal resection-anastomosis was performed after removal of two separate tumors in the small intestine. Histopathological result indicated metastatic adenocarcinoma. The patient had not been diagnosed as any carcinoma or lung disease previously. The postoperative thorax computed tomography scan showed a lesion at the right lung, which was pathologically defined as adenocarcinoma of the lung by bronchial brushing. This case is reported to arouse a clinical suspicion of intestinal metastasis in undiagnosed primary lung cancer presenting with acute abdominal pain. Early diagnosis and treatments are vital for improving survival of the patients.
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PMID:Undiagnosed primary lung carcinoma with initial manifestation of intestinal obstruction: A case report and literature review. 2632 14