Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0740577 (acute abdominal pain)
 1,982 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The clinical diagnosis of acute colonic diverticulitis (ACD) is at times difficult and an early detection by a non-invasive method as ultrasonography (US) is required. The aim of this study is to evaluate the diagnostic sensibility of US performed on admission in patients with ACD, its value in monitoring assessment of severity and its influence on surgical decision. The Authors have carried out a retrospective study on 22 patients (8 men and 14 women, median age 58 years) admitted from January 1997 to June 1999 for ACD. In 21 cases the diagnosis was made on admission by US. The diagnostic sensibility was 95.5% (false-negative: 1 case). The true diagnosis in 2 false-positive patients was: ischemic colitis (1 case), aspecific thickening of colonic wall in patient with left renal carcinoma (1 case). The sensibility of clinical evaluation on admission was 68% (false-negative: 7 cases). The clinical diagnosis was unequivocal in only 36.4% of cases. In 14 patients, successfully treated conservatively, the US gave monitoring the reduction of hypoechogenic thickening of the colonic wall. Seven patients who underwent urgent surgery: in 3 cases for generalized peritonitis, but in 4 patients (18.2%) the immediate management was influenced by US detection of a clinical misdiagnosed abscess. The Authors conclude that, in the hands of an expert investigator, the extensive use of US in acute abdominal pain facilitate an accurate diagnosis of ACD and its appropriate management.
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PMID:[Ultrasonography of acute colonic diverticulitis. Effect on surgical treatment]. 1091 53

Gallbladder metastases are very rare and usually arise from malignant melanoma, renal cell carcinoma and cervical carcinoma. Breast carcinoma metastatic to the gallbladder is extremely rare and only 4 cases have been reported in the English literature. We hereby report a 54-year-old lady who was diagnosed as having breast carcinoma and underwent modified radical mastectomy. One month after the operation, she developed acute abdominal pain and underwent cholecystectomy after clinical investigation. Histopathological examination revealed metastasis to the gallbladder. Being considered a patient with metastatic breast carcinoma she was subjected to taxane and anthracycline-based palliative chemotherapy. Later she had CNS involvement and died of the progressive disease soon after few months.
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PMID:Breast carcinoma with metastasis to the gallbladder: an unusual case report with a short review of literature. 1669 97

Renal cell carcinoma (RCC) may metastasize to almost any organ, but metastasis to the small bowel is rare. Small bowel metastasis from RCC can induce obstruction or bleeding, and perforation can also be induced in rare case. Yet RCC metastasis to the small bowel is unlikely to be a direct cause of intussusceptions. A few cases of intussusceptions caused by small intestinal metastasis of RCC have been reported, but multiple small intestinal intussusceptions are extremely rare. We report here on a 47-year-old male patient who presented to the emergency room with acute abdominal pain. He had undergone radical nephrectomy 2 years previously due to left RCC. The abdominal CT scan revealed enhanced masses with the "target" sign that suggested enteric intussusceptions in the jejunum. Eight pedunculated masses within the small intestinal lumen led to intussusceptions at 30 and 150 cm distal to Treitz ligament. Three segmental resections of the small intestine and functional end to end anastomosis were done. The patient recovered uneventfully from this operation. To the best of our knowledge, this is the 1(st) report of metastases from RCC that presented as synchronous intraluminal polypoid tumors, and these tumors served as the lead points for two intussusceptions in the jejunum.
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PMID:A case of multiple intussusceptions in the small intestine caused by metastatic renal cell carcinoma. 1968 56

Here we report a rare case of coexisting renal cell carcinoma (RCC) with leiomyomatous stroma and a ruptured adrenal aneurysm. The patient was a 75-year-old woman with acute abdominal pain. Imaging studies showed a left peri-renal hematoma and a mass in the left kidney. Left nephrectomy and adrenalectomy were performed. Pathological examination showed a ruptured aneurysm in the left adrenal gland. The renal mass was composed of tubules and acini of epithelial cells and a prominent leiomyomatous stroma. The tumor cells were positive for carbonic anhydrase IX, cytokeratin 7, and negative for AMACR, consistent with clear cell (tubulo) papillary RCC.
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PMID:A Rare Case of Renal Cell Carcinoma With Leiomyomatous Stroma and Concomitant Ruptured Adrenal Aneurysm. 2751 74