Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0740577 (acute abdominal pain)
 1,982 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 48-year-old patient known to have Crohn's disease (diagnosis verified by clinical findings, histology and colonoscopy) was admitted to the hospital with acute abdominal pain. Additional examination did not suggest another pathology. Acute mesenteric ischaemia was suspected late and diagnosed only during laparotomy. CT scan and MR were normal, but abdominal angiography confirmed total occlusion of the superior mesenteric artery. In this case the outcome was death.
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PMID:[Acute mesenteric ischaemia in a patient with Crohn's disease]. 1727 29

In spite of introduction modern diagnostics and therapeutics modalities in clinical practice diagnostics of acute intestinal ischaemia is very difficult. Acute intestinal ischaemia is rare cause of acute abdominal dissease but results of surgical treatment and prognosis of the patients with acute intestinal ischaemia is very poor. The aim of study is occurence, diagnostics and therapeutics possibilities of acute intestinal ischaemia, because tretament of acute intestinal ischaemia have high rate of mortality. Authors claiming on own small set of patients that in diagnostics of acute abdominal pain everything in once mind on acute intestinal ischaemia.
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PMID:[Acute intestinal ischaemia]. 1762 60

Acute mesenteric ischemia (AMI) is one of the most severe diagnostic and therapeutic vital emergencies. This affection is characterized by the insufficient blood supply to the gastrointestinal tract, related to an occlusive or non-occlusive mechanism, resulting in an ischemic and inflammatory injury that may progress to necrosis of the intestinal wall. The clinical picture is nonspecific, dominated by acute abdominal pain. At present, no early biological marker is commonly used in clinical practice for diagnostic purposes. The purpose of this review was to review the markers that have been evaluated in this condition. Among the biological blood markers which have shown a diagnostic interest in the IMA, there are notably the two stereoisomers of lactate (D and L), D-dimers, and alpha glutathione transferase. More specific markers include the intestinal fatty acid binding protein or I-FABP, which is a marker of enterocyte necrosis, citrulline, a marker of enterocyte mass, or Smooth muscle protein 22 (SM22) marker for muscle damage. The early diagnosis of intestinal ischemia remains a challenge. It is likely that in the future IMA's biomarker research will be better customized and adapted to the physiopathological mechanism. More global approaches (proteomics, metabolomics) should also make it possible to identify new biomarkers.
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PMID:Biomarkers for acute mesenteric ischemia diagnosis: state of the art and perspectives. 3122 1

Acute mesenteric ischemia is an abdominal emergency because reduced blood flow to bowel loops rapidly leads to irreversible necrosis and death. This paper reviews the different conditions (arterial, venous, low-flow states) that can result in reduced blood flow to bowel loops. Since the clinical and laboratory findings are nonspecific, imaging tests play an important role in the diagnosis of mesenteric ischemia. Multidetector computed tomography is the first-choice technique for the initial workup in cases of suspected acute mesenteric ischemia because it can rule out other causes of acute abdominal pain. It is important to know the characteristic radiological signs of this entity, because early diagnosis is essential to prevent progression to life-threatening intestinal necrosis.
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PMID:Acute mesenteric ischemia: a review of the main imaging techniques and signs. 3238 83