Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0740441 (acute diarrhea)
2,275 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Sucrose absorption was studied by the Breath Test method (BTH) in 41 infants presenting with acute diarrhea. In 28, studies were performed in children treated orally with a 40% sucrose solution. Malabsorption was demonstrated in 8 cases. In 36 infants, sucrose loading test (1 g/kg) was carried out between the 3rd and the 7th days of the diarrhea: malabsorption was present in 9 cases. Malabsorption was transitory in all children. The frequency of this sucrose malabsorption during acute diarrhea is not sufficient to prevent the therapeutic use of sucrose solution, but differs from the usual lack of sucrose malabsorption in chronic diarrhea, even, as shown here, in children with complete villous atrophy.
...
PMID:[Breath test study of sucrose absorption in infants with acute diarrhea ]. 712 38

Based on studies showing improved absorption of hypo-osmolar oral rehydration solutions (ORS) with reduced glucose and sodium concentration, a hypo-osmolar ORS with sucrose replacing glucose (sodium 60, potassium 15, chloride 60, citrate 5, sucrose 58 mmol l-1, calculated osmolality 198 mOsm kg-1) was compared with mildly hyperosmolar glucose ORS (WHO) in 46 children aged 6-30 months with acute diarrhoea and dehydration. In the hypo-osmolar sucrose ORS group (n = 18) faecal output was less by 30% during the initial 24 and 48 h compared with controls, suggesting better absorption. Sucrose may be a suitable alternative to glucose in an absorption-efficient hypo-osmolar ORS.
...
PMID:Hypo-osmolar sucrose oral rehydration solutions in acute diarrhoea: a pilot study. 892 94