Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0740441 (acute diarrhea)
2,275 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A protocol of nutritional rehabilitation using fermented milk, vegetable oil and caster sugar has been tested on 54 Senegalese children, aged 6-36 months, admitted with acute diarrhoea and malnutrition. At the time of admission, 39 per cent of children were dehydrated and 26 per cent had sugar intolerance. In the course of treatment three went home against medical advice and one died from acute pneumonia with respiratory-heart failure. Among the cases of marasmus there were no differences in mean weight gain between children with sugar intolerance and others despite a longer duration of diarrhoea in the first group. Furthermore, the experimental protocol has never been compromised because of worsening diarrhoea or weight loss. These results indicate that a formula based on fermented milk together with oral rehydration can be used to treat malnourished children with acute diarrhoea and sugar intolerance.
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PMID:Management of malnourished children with acute diarrhoea and sugar intolerance. 235 9

A protocol of nutritional rehabilitation using fermented milk, vegetable oil, and castor sugar has been tested on 54 Senegalese children age 6-36 months admitted with acute diarrhoea and malnutrition. At time of admission, 39 per cent of children were dehydrated and 26 per cent had sugar intolerance. In the course of treatment three absconded and one died from acute pneumonia with respiratory and heart failure. Among those with marasmus there were no differences in mean weight gains between children with sugar intolerance and others, despite a longer duration of diarrhoea in the first group. Furthermore, the treatment protocol has never been compromised because of worsening diarrhoea or weight loss. These results indicate that a formula based on fermented milk together with oral rehydration can be used to treat malnourished children with acute diarrhoea and sugar intolerance.
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PMID:Management of malnourished children with acute diarrhoea and sugar intolerance. 251 80

Acute diarrhoea is still a leading cause of child mortality and morbidity, second only to pneumonia as a killer of children, in India and Indonesia. Untreated diarrhoea precipitates malnutrition and is often the underlying cause of marasmus and kwashiorkor. Shigella and salmonella dysenteries are responsible for about 60% of all cases in Indonesia and India. These bacillary agents respond well to trimethoprim. Amoebiasis responds well to metronidazole. Most cases can be managed in the home, even if the exact cause is unknown, by giving liquids or a simple rehydration drink. Diarrhoea can be prevented by improving communal sanitation and personal hygiene, and by giving breast as opposed to bottle feeding of infants. Earlier introduction of supplementary feeding could provide the child with higher energy reserves giving it a better chance of survival when diarrhoeal insults occur.
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PMID:Acute diarrhoeal disease in India and Indonesia. 281 85

In Riyadh, Saudi Arabia, gastroenteritis is a leading cause of admission to Children's Hospital. A prospective study of 254 children between the ages of 0-5 admitted over a 4-month period for acute diarrhea was undertaken. Information was obtained from parents about each child's history and the children were medically examined and weighed before and after treatment. Blood urea and electrolytes were estimated and stools examined for parasites and bacteria. Almost 85% of the babies were under 1 year old, 46.5% were less than 5 months. 35.6% had normal weights for age; 25.6%, 1st degree malnutrition; 26.4%, 2nd degree and 12.4%, 3rd degree malnutrition. The severely malnourished were all marasmic, except for 6 who had kwashiorkor, alone or with marasmus. 65.4% were bottle fed but only 20% of the mothers used boiling or chemical means of sterilizing the bottles. Isonatremic dehydration accounted for 73% of the dehydrated infants or children, hyponatremia for 14% and hypernatremia for 13%. 11.8% were graded severely dehydrated on admission. Mothers of children with hypotonic dehydration tended to dilute the feeds, while mothers of hypertonic dehydrated children tended to concentrate them. The overall isolation rate for bacteria and parasites was 33.8%, including salmonella, entero-pathogenic E. coli, Giardia lambia and shigella species. 23 children died; mortality was highest in the younger age group, among babies who were bottle fed, among the more severely dehydrated and among those with hypertonic and hypotonic dehydration. The study results are comparable with incidence reported in proximal areas. The high incidence of bottlefeeding and the consequences to infant health as a major cause of morbidity is of concern. The mild cases of dehydration could be treated on an outpatient basis if adequate facilities are accessible to the population.
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PMID:Gastroenteritis among children in Riyadh: a prospective analysis of 254 hospital admissions. 618 53

Forty-five marasmic infants were studied for plasma zinc and copper levels. They were selected from those children admitted to a nutritional recovery center. The mean plasma zinc level was 92.4 +/- 24 micrograms/dl (mean +/- SD); 7% of the infants had low zinc values as defined by zinc less than 70 micrograms/dl. Median copper was 90 micrograms/dl (range 27-172) and 49% of the children had copper levels below 90 micrograms/dl (established as our normal limit). Birth weight, breast feeding and prior hospitalization for acute diarrhea with dehydration were studied as antecedents related to low Cu and Zn. Children with prior diagnosis of acute diarrhea and hospitalization had lower copper levels than those sent from primary care centers. Breast feeding was associated with higher Cu levels. No relationship was found between zinc levels and those antecedents, but differences were found in regard to the degree of malnutrition, season of the year and Zn status. In this investigation no Zn deficiency was found in marasmus cases. Hypocupremia, however, is a very significant problem in marasmic infants, especially when associated with early weaning and the presence of previous hospitalization for acute diarrhea.
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PMID:[Plasma zinc and copper in infants with protein-calorie malnutrition]. 644 37

To identify possible risk factors for persistent diarrhoea, 307 children with acute diarrhoea presenting at the University College Hospital, Ibadan, Nigeria over a 10-month period from July 1993 to April 1994 were followed up prospectively until the resolution of the illness. The children were aged 6-60 months. In 36 (11.7%) of them, diarrhoea became persistent (i.e. lasted more than 14 days). This hospital frequency of 11.7% of persistent diarrhoea is, as expected, higher than the figures from previous community-based studies of diarrhoea from Nigeria. The major factor associated with persistent diarrhoea was poor nutritional status. Mean z scores of weight-for-height and weight-for-age were significantly lower in the persistent diarrhoea group, while mean z scores of height-for-age were similar in the two groups. The frequencies of occurrence of undernutrition, marasmus and kwashiorkor were also higher in the persistent diarrhoea group. Therefore, in common with studies from other regions of the world, malnutrition is an important risk factor for persistent diarrhoea in this group of Nigerian children. The implication of these findings is that reduction in the prevalence of malnutrition may be associated with reduction in the proportion of acute diarrhoeal episodes that eventually progress to persistent diarrhoea.
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PMID:Persistent diarrhoea in Nigerian children aged less than five years: a hospital-based study. 947 79