Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0740441 (acute diarrhea)
 2,275 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

"Pouchitis" is a well recognised complication of restorative proctocolectomy characterised by acute diarrhoea, sometimes with blood, often complicated by incontinence, malaise, arthritis, erythema nodosum and fever. The ileal mucosa is hyperaemic, there may be shallow ulcers and contact bleeding. Biopsies characteristically show villous atrophy, a poly-morphonuclear infiltrate and chronic inflammatory cells, but the histopathological features are often patchy and may be difficult to differentiate from ischaemic ileitis, colonic metaplasia or Crohn's disease. "Pouchitis" is probably due to an overgrowth of intestinal bacteria secondary to stasis but there is some evidence that there may be an ischaemic factor. Most patients respond rapidly to oral metronidazole.
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PMID:["Pouchitis"; histology]. 816 Nov 30

Yersinia enterocolitica infection presents a wide clinical spectrum; in infants and young children it usually presents as uncomplicated acute diarrhea, while in older children and adolescents it more frequently presents as terminal ileitis and/or mesenteric adenitis. We describe two infants who developed terminal ileitis complicating Y. enterocolitica infection, which is exceptionally rare. The clinical, laboratory and radiologic findings are described and ultrasound study is emphasized as a simple and reliable tool for investigation of terminal ileitis.
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PMID:[Terminal ileitis due to Yersinia enterocolitica in infants]. 1632 23

Yersinia enterocolitica, an important food- and water-borne enteropathogen causes acute diarrhea, terminal ileitis, and mesenteric lymphadenitis. It is represented by six biovars (1A, 1B, 2-5). The biovar 1A strains are generally regarded as avirulent as they lack pYV plasmid and major chromosomal virulence genes. Despite this, some biovar 1A strains produce disease symptoms indistinguishable from that produced by known pathogenic biovars (1B, 2-5). Suggested prospective studies to understand pathogenic potential of biovar 1A should focus on role of insecticidal toxins, urease, protease, superoxide dismutase, and host responses. These studies should also take into account the clonal groups of biovar 1A.
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PMID:The enigma of Yersinia enterocolitica biovar 1A. 2088 83