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Query: UMLS:C0729233 (Thoracic)
 6,478 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Thoracic tumors have been infrequently reported as a complication of neurofibromatosis-1 (NF1). To determine the prevalence and clinical features of thoracic tumors seen in children with NF1, we reviewed medical records and imaging studies for a group of 260 pediatric patients with NF1 followed in a multidisciplinary NF Center. Extrapleural thoracic tumors were seen in nine patients with NF1, corresponding to a prevalence of 3.5% in this hospital-based series of patients. Pathological studies of the tumors demonstrated plexiform neurofibroma in four cases and neurofibrosarcoma in one case. The remaining four cases were suspected to be plexiform neurofibroma based on clinical features but have not been confirmed histologically. Three patients presented with symptoms of chest pain, syncope, or wheezing; six patients were asymptomatic at the time of diagnosis of the tumors. Physical findings frequently found in patients with thoracic tumors were scoliosis (especially focal scoliosis) and visible plexiform neurofibromas of the neck. We conclude that NF1 patients presenting with any of these signs and symptoms should be screened for thoracic tumors with chest X-ray and magnetic resonance imaging as needed. It is unknown whether screening asymptomatic NF1 patients with chest X-rays on a regular basis will result in an improved outcome.
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PMID:Thoracic tumors in children with neurofibromatosis-1. 934 7

Causes of postoperative spinal imbalance in patients with idiopathic scoliosis treated with multisegmental posterior instrumentation CD or TSRH and posterior fusion are presented. Investigation included 88 patients (77 girls, 11 boys) aged 11.4-17.1 (mean 13.8). Primary curve Cobb angle ranged from 52 (to 133 mean 75), secondary curve 16 (to 88 mean 47). Follow-up ranged from 12 to 19 months (mean 18.2 months). In 31 patients (35.2%) postoperative decompensation of the spine occurred. Six of them regained spinal balance within 12 to 19 months postoperatively. As the magnitude of correction increased in relation to preoperative correctiveness and/or preoperative rotation of the spine the imbalance of the spine was more pronounced. It was worsened also in cases where spontaneous correction within the secondary curve (not instrumented) was lesser than expected. Thoracic curve overcorrection in type II scoliosis with instrumentation inclusive of 1 or 2 vertebrae beyond neutral one resulted in decompensation to the left. To short a fusion (in relation to neutral and stable vertebrae) caused in this type as well as in type II and IV right sided decompensation. Overcorrection of lower (right sided) curve or omission of upper (left sided) curve in type V scoliosis caused shoulder girdle decompensation. In type I lumbar fusion done proximally to neutral and stable vertebrae caused left side decompensation of the spine.
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PMID:[Surgical treatment of idiopathic scoliosis with multisegmental posterior instrumentation and its influence on postoperative spinal balance]. 949 Feb 55

Forty-one patients with thoracic adolescent idiopathic scoliosis (AIS) treated with only a posterior spine fusion using specialized pedicle hooks (SPH) (hooks augmented with 3.2-mm screws) at the apex of the curve were reviewed in order to assess the effectiveness of this correction method. Inclusion in the study group required a minimum of 2 years' follow-up and the same strategy of correction where the apical vertebrae (3 or 4 vertebrae on the concave side) were instrumented with SPH. The mean preoperative Cobb angle was corrected from 55 degrees (42 degrees -80 degrees) to 18 degrees (67%) postoperatively and to 23 degrees (58%) at the last follow-up (28-50 months) for a flexibility index of 46%. Apical vertebral translation was corrected to 70% at the last follow-up. Thoracic kyphosis remained unchanged, from 23 degrees to 26 degrees, and the lumbar lordosis went from -53 degrees to -59 degrees. The lumbar curve was corrected from 38 degrees to 18 degrees. Coronal balance improved from 10 to 1 mm; shoulder balance was improved from 15 to 5 mm. The rib hump was improved from an average of 30 mm preoperatively to 15 mm postoperatively, but only to 25 mm at the last follow-up (17% of correction). One case of a spastic bladder was observed postoperatively, which resolved completely after 8 months. Three patients had to have their instrumentation removed because of pain. There was no complication related to the use of the SPH. The authors conclude that apical correction with SPH allows effective scoliosis correction without spinal distraction and does not require supra- or infralaminar hook in the spinal canal.
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PMID:Adolescent idiopathic thoracic scoliosis: apical correction with specialized pedicle hooks. 1048 27

Three instrumentation systems were tested using a unilateral rod construct for instrumenting thoracic scoliosis. Thoracic calf spines were instrumented with Texas Scottish Rite Hospital (TSRH), Cotrel Dubousset (CD), and Isola single-rod instrumentation systems. The constructs were mechanically tested, and rotational displacement and torsional stiffness were determined. The TSRH instrumentation was found to have significantly less rotational displacement and to be significantly stiffer in torsion than the uninstrumented control. The CD and Isola systems were not significantly different than the uninstrumented calf spine.
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PMID:Torsional stiffness of a single-rod construct using three instrumentation systems for thoracic scoliosis. 1054 9

Sixty cases of congenital scoliosis over a 13-year period were studied. The female:male ratio was 1.4:1. The deformity usually presented itself first either at 2 or 8-13 years of age. A positive family history was present in five cases, and parental consanguinity was observed in 40% of patients. Five patterns of deformity were recognized. Hemivertebra was the most common type, and unilateral unsegmented bar with contralateral hemivertebra was the most severe and most progressive pattern of deformity. Thoracic curves were more prevalent while larger curves were more commonly seen in the thoracolumbar area. The curves measured >40 degrees in 70% of the patients who had reached maturity. The curve progression index was 9 degrees for unilateral unsegmented bar with contralateral hemivertebra, and 6 degrees without contralateral hemivertebra. This index was 1.5 degrees for hemivertebra and complex type of deformity, and 0.5 degrees for block vertebra. Unbalanced fully segmented hemivertebra was next after the two types of unsegmented bars in terms of potential for progression. Presence of fused ribs on concave side of lower thoracic curves increased the rate of curve progression. Spinal dysraphism, diagnosed in 20% of cases, was the most commonly associated anomaly.
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PMID:Patterns and progression in congenital scoliosis. 1057 48

Eighteen patients with idiopathic scoliosis who underwent posterior spinal correction and fusion using Cotrel-Dubousset instrumentation between 1991 and 1996, were evaluated for curve correction and complications. Age at surgery averaged 14.7 years. Follow-up averaged 3.7 years. Thoracic curve correction averaged 65 per cent in those with King type III/IV curves and 51 per cent in those with King type II curves. At the recent follow-up, correction loss averaged 12 per cent and 8 per cent, respectively. Lumbar curve correction averaged 31 per cent after instrumentation in type II curves, with a loss of approximately 3 per cent correction at follow-up. Thoracic sagittal contour improved 14 degrees for hypokyphotic patients. Apical vertebral rotation improved an average of 37 per cent after derotation maneuver of the left side rod. No neurologic complications or deep infection occurred. In conclusion, frontal and sagittal thoracic curve correction can be satisfactorily achieved using Cotrel-Dubousset instrumentation.
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PMID:Treatment of adolescent idiopathic scoliosis using Cotrel-Dubousset spinal instrumentation. 1071 Aug 83

Previous studies have reported varying success rates with the use of the Charleston brace in idiopathic scoliosis. However, these studies have included patients from multiple centers, those with double curves, and those still undergoing treatment. This article presents the results of Charleston bracing in 42 skeletally immature patients (Risser 0/1) treated at one institution and followed up for a mean of 3.3 years after brace discontinuation. Selection criteria included a diagnosis of idiopathic scoliosis, Risser stage 0 or 1, at least 10 years of age at the time of bracing, female gender, a single curve between 25 degrees and 40 degrees, and no prior treatment. The average age at the time of bracing was 12.5 years (range 10-15) and the average curve was 30.3 degrees (range 25 degrees -40 degrees ). Outcome was considered a failure if the curve had increased more than 5 degrees at last follow-up, if surgical intervention was required, or if there was a change of orthosis during treatment (e.g., Charleston to Boston). In 25 of the 42 patients (60%), the brace was successful in preventing progression of the curve (mean follow-up 3.4 years; range 1.1-11.7). Thoracic curves had the same success as thoracolumbar and lumbar curves. Based on these results, the authors conclude that the Charleston brace is effective in preventing progression of curve. Proper patient selection is important.
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PMID:Results of Charleston bracing in skeletally immature patients with idiopathic scoliosis. 1213 58

Thoracic volume was calculated in 50 adolescent patients operated on for severe idiopathic thoracic scoliosis. In 25, anterior instrumentation was used (group 1), and posterior instrumentation in the other 25 patients (group 2). Calculation of thoracic volume was made from measurements of pre-operative and post-operative radiographs. The mean spinal curvature in group 1 was 73+/-12.4 degrees before the operation, and 19+/-15 degrees after the operation, and in group 2 the curvature was 75+/-13 degrees before the operation and 37+/-10 degrees after the operation. The calculated thoracic volume in the group with anterior instrumentation increased from 5234 ml pre-operatively to 6043 ml post-operatively, while with posterior instrumentation it increased from 5155 ml to 5489 ml. The correlation between the change in the Cobb angle and the thoracic volume change was poor for both groups. To determine the role in the thoracic volume increase of the frontal, sagittal and vertical thoracic diameters, further correlation tests were made between these and the thoracic volume increase in each diameter. The best correlation was found between the frontal and vertical increase of diameters in group 1, whereas in group 2 the best correlation was found between the volume increase and the sagittal parameters.
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PMID:Scoliosis curve correction, thoracic volume changes, and thoracic diameters in scoliotic patients after anterior and after posterior instrumentation. 1140 53

The sagittal and frontal profiles of the entire spine are poorly studied in lumbosacral spondylolisthesis. It was the purpose of this study to further investigate these profiles. Standing posterior-anterior and lateral radiographs in 24 children with lumbosacral spondylolisthesis were reviewed (18 isthmic, 6 congenital). Cervical lordosis, lumbar lordosis, thoracic kyphosis, sagittal vertebral axis, sacral inclination, slip magnitude, slip angle, and sagittal rotation were measured. Cobb magnitude, Risser sign, curve location, and direction were noted for those with scoliosis. Relationships between sagittal variables were explored (Pearson correlation). The average age of patients was 14.7 +/- 2.5 years, slip magnitude was 38 +/- 38%, slip angle was 5 +/- 31 degrees, sagittal rotation was -6 +/- 31 degrees, thoracic kyphosis was 29 +/- 16 degrees, cervical lordosis was -1 +/- 12 degrees, and lumbar lordosis was 62 +/- 22 degrees. Correlations were noted between thoracic kyphosis and sacral inclination, percent slip, slip angle, and sagittal rotation. Sacral inclination decreased as the slip increased. Scoliosis was present in 10 children, with an average curve of 19 +/- 6 degrees. Thoracic kyphosis was less in those with scoliosis (21 +/- 25 degrees versus 33 +/- 25 degrees, p = 0.033). In children with lumbosacral spondylolisthesis, the sacrum becomes more vertical as the slip worsens. As the sacrum becomes more vertical, the thoracic spine becomes more lordotic, which is likely an adaptive mechanism used by the body to maintain forward visual gaze.
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PMID:Profiles of the cervical, thoracic, and lumbosacral spine in children and adolescents with lumbosacral spondylolisthesis. 1172 94

As scoliotic curve is a rotational deformity, derotation maneuvre was used as the corrective factor, but recent studies demonstrated spinal imbalance and decompensation problems in patients treated with this method. This study evaluates 217 late onset idiopathic scoliosis patients surgically treated with third generation instrumentation (Texas Scotish Rite Hospital System - TSRH) from September 1991 to November 1996 with a minimum 2 years follow up. Preoperative and postoperative Cobb angles in the frontal plane and thoracic kyphosis and lumbar lordosis angles in the sagittal plane are measured. The balance was analyzed clinically and radiologically by measurement of the lateral trunk shift (LT), shift of head (SH) and shift of stable vertebra (SS) in vertebral unit (VU). At final follow - up correction loss, infection and other complications were documented. Mean age of the patients was 14.8 +/- 2.3 and mean follow up period 55.8 +/- 29.5 months. When all the patients were included, preoperative mean Cobb angles of major curves in the frontal plane was 59.1 +/- 20.7 degrees. Major curves that were corrected by 34.8 +/- 20.5 % in the bending radiograms were achieved by 58.9 +/- 19.5 % correction postoperatively. At the last control, 7.3 degrees +/- 6.4 degrees of correction loss was recorded in major curves in the frontal plane. Also postoperative kyphosis angle and lumbar lordosis angles were 31.4 degrees +/- 11.6 degrees and 30.6 degrees +/- 10.9 degrees respectively. Postoperatively, a statistically significant correction was obtained in LT, SH and SS values. None of the patients had complete balance (SH: 0 VU, SS: 0 VU) preoperatively. Only 39.2 % of the patients had clinically balanced curves (0 VU < SH < 0.5 VU and 0 VU < SS < 0.5 VU). Postoperatively, 47.9 % of the patients were found to be completely balanced, while 43.8 % had a balanced curve. Overall 91.7 % of the patients had a trunk balance after surgical intervention. The remaining 8.3 % imbalanced curve rate raised up to 16.6 % at final follow up, but the loss of correction rates in S S and SH values were found to be insignificant. The postoperative "imbalance" problem was mostly seen in Type II and Type IV curves. However, at final follow up, the imbalance problem due to overcorrection which became evident especially by "shift of head" to opposite side was seen in all types of curves. It is established that high correction rates can be obtained in scoliotic curves with third - generation instrumentation. No undue effects were observed in the uninstrumented lumbar curves. Thoracic sagittal contours of the hypokyphotic patients were improved. Use of this instrumentation system causes minimal imbalance problems and with proper preoperative planning high correction rates can be achieved.
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PMID:Frontal and sagittal balance analysis of late onset idiopathic scoliosis treated with third generation instrumentation. 1187 Mar 34


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