Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0729233 (
Thoracic
)
6,478
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Spinal fusion was performed in 23 patients with congenital
scoliosis
. Various procedures were used including posterior fusion and without instrumentation. No surgical procedure proved to be superior for obtaining correction regardless of the use of supplemental instrumentation. The use of Knodt or Harrington Instrumentation could not be correlated with a lower pseudoarthrosis rate, shorter postoperative immunobilization period, or a decrease in postoperative loss of correction. The morbidity associated with these surgical procedures was high (48%).
Thoracic
curves were more prone to lengthen or develop kyphoses postoperatively. A high incidence of varied congenital anomalies was found in association with congenital
scoliosis
. A through work-up including an intravenous pyelogram and myelogram is strongly recommended prior to the operative treatment of congenital
scoliosis
.
...
PMID:The operative treatment of congenital scoliosis. A report of 23 patients. 50 23
In 4 patients with juvenile idiopathic thoracic
scoliosis
an atelectasis as part of the convex-sided lungs was found. In all cases there was a small sagittal diameter of the chest; the atelectases were situated in the right lower and middle lobe and caused by the close topographical relation of large bronchi and scoliotic spine (sometimes compression of the bronchus) demonstrable by tomography, bronchoscopy and bronchography. The therapeutic approach of these atelectases is discussed.
Thoracic
casting either for conservative correction and treatment of
scoliosis
or as postoperative immobilisation after fusion was done. In all cases, it may influence the occurrence of an atelectasis.
...
PMID:[Atelectases as part of the convex-sided lungs in thoracic scoliosis (author's transl)]. 71 53
The posteroanterior and lateral chest X-ray films of 64 consecutive patients with an isolated systolic click (55 patients) or a systolic click with a late systolic murmur (9 patients) showed a striking frequency of thoracic skeletal abnormalities. There were 50 female and 14 male subjects. The average age of the female subjects was 36.7 years (range 13 to 67), that of the male subjects 39.7 years (range 17 to 56). Seventy-two percent of the female and 78 percent of the male subjects had an anteroposterior/transverse thoracic ratio less than the mean ratio in a small population. Bony abnormalities such as pectus excavatum, straight thoracic spine and
scoliosis
occurred alone or in a combination in 31 of the 50 female patients (62 percent) and in 8 of the 14 male patients (57 percent). Overall, 39 of the 64 patients (61 percent) had at least one of the skeletal abnormalities.
Scoliosis
occurred in 25 subjects (39 percent) and was mild in 19. A "straight back" was found in 15 (23 percent) and pectus excavatum in 7 patients (11 percent). The explanation for these findings is not apparent.
Thoracic
cage abnormalities should be included as one of the nonauscultatory features of the systolic click-late systolic murmur syndrome.
...
PMID:Radiographic appearance of the thorax in systolic click-late systolic murmur syndrome. 114 94
Idiopathic prolapse of the mitral valve is a common disorder, but many cases are clinically subtle.
Thoracic
skeletal abnormalities, reported recently to accompany the syndrome, may serve as an easily identifiable clinical indicator. The prevalence of these abnormalities was defined in 24 patients with proved prolapse of the mitral valve. The valvular syndrome was defined clinically, by echocardiography and, in seven cases, by left ventricular angiography. The skeletal deformities were defined clinically and radiographically. Pectus excavatum was present in 62 percent of the patients, "straight back" in 17 percent and severe
scoliosis
in 8 percent. Eighteen of the 24 patients (75 percent) had a definite thoracic skeletal deformity. The association of idiopathic prolapse of the mitral valve with these skeletal deformities may represent a forme fruste of Marfan's syndrome. Patients with "straight back" and pectus excavatum should be examined clinically and perhaps by echocardiography to exclude idiopathic prolapse of the mitral valve; when murmurs are present, a diagnosis of "pseudoheart disease" should not be made before mitral valve prolapse has been excluded.
...
PMID:Thoracic skeletal abnormalities in idiopathic mitral valve prolapse. 114 95
110 patients with idiopathic
scoliosis
are reported on, who had no treatment for 2 years or more before growth stopped. Another 36 patients untreated for 1 year could be observed. The changes in the scoliotic angle were followed up radiologically and entered into a diagram. The average progression of these scolioses during one year were calculated. Progression was always most pronounced between the 10th and 15th year and coincided with the prepubertal increase in growth. This has to be expected 2 years later in boys than in girls. The degree of progression definitely depended on the site of the primary curve.
Thoracic
and S
scoliosis
showed most pronounced progression, followed by thoracolumbar and lumbar
scoliosis
. Progression was worse the earlier
scoliosis
was diagnosed.
...
PMID:[Progression of untreated idiopathic scoliosis up to the end of growth]. 115 43
Cartilage-hair hypoplasia is a metaphyseal chondrodysplasia with short-limbed short stature. In childhood radiographs the metaphyseal regions of the tubular bones are widened, scalloped and irregularly sclerotic. We have analyzed radiological characteristics and skeletal growth in 149 radiographic surveys of 82 Finnish patients. All extremity long bones were affected and short for age. The growth failure was progressive. In the adults the median relative lengths were for the humerus -6.3 SD, radius -8.6 SD, ulna -6.7 SD, femur -9.7 SD, tibia -8.7 SD, and fibula -6.8 SD. the severity of the metaphyseal changes correlated with the degree of the growth failure. The skeletal age was markedly retarded in 14% of the patients. Caudal widening of the interpediculate distance in the lumbar spine was observed in 90% of the patients, but it tended to be less than normal. The sagittal diameter of the spinal canal was normal in the cervical region but decreased in the lumbar region. Mild
scoliosis
was observed in one-fourth of the patients, and its incidence increased with age. Lumbar lordosis was moderately increased.
Thoracic
deformity was observed in 82% of the patients. The relative interorbital distance was increased with the median of +2.2 SD in the adults.
...
PMID:Skeletal growth in cartilage-hair hypoplasia. A radiological study of 82 patients. 143 68
Clinical characteristics of 60 (41 males, 19 females) patients with echocardiographically proven mitral valve prolapse were analysed, with special interest in the associated thoracic skeletal abnormalities. There was a male preponderance (2.2:1) and 91.7% of patients were symptomatic--atypical chest pain, palpitations, exertional dyspnoea and easy fatiguability being the major symptoms. Sixty seven percent had an asthenic body habitus, and 55% had high-arched palate.
Thoracic
scoliosis
(55%), straight back syndrome (50%), flat chest (46.7%), and pectus excavatum (20%) were seen in association with the condition, with 81.7% having any one or combination of these features. Lateral chest radiography showed pancaking of heart shadow in 48.3%. Isolated non-ejection systolic click(s) was the major cardiac auscultatory finding (61.7%), while 60% showed pansystolic prolapse on echocardiography. Electrocardiographic ST-T-U changes in the inferior and/or lateral chest leads were seen in 46.7%, while 16.7% had cardiac arrhythmias. None had infective endocarditis, heart failure or cerebral embolic events. The findings corroborate the view that thoracic skeletal anomalies may be regarded as non-auscultatory features of this syndrome.
...
PMID:Mitral valve prolapse syndrome and associated thoracic skeletal abnormalities. 130 Oct 49
Thoracic
ratios (TRs) were measured segmentally (T1-12) in the chest radiographs of 412 children aged 0-17 years attending hospital with minimal disorder or diseases (boys 193, girls 219). A new method for measuring TRs was used which calculates the width of the left hemithorax, the right hemithorax and the total thorax relative to T1-T12 distance. The data were analysed in 3 age groups--infancy, childhood and puberty, after the classification of Karlberg (1989). The findings are as follows. 1. The chest broadens from T1 to about T10-11. 2. Between infancy and childhood, relative to its length the chest narrows from above downwards and particularly in the lower chest (T5-12 average diminution, boys 9.5%, girls 9.8%). In the upper chest, the narrowing is more marked in girls than boys (T1-4 average diminution, boys 5.1%, girls 8.2%). 3. Between childhood and puberty, the girl's but not the boy's chest narrows further in its lower half (below T6 average diminution 3.3%). At T6 and above there is no detectable change in the relative width of the chest in either boys or girls. 4. The relative narrowing of the chest during growth appears to result from several mechanisms: (1) elevation of upper rib-vertebra angles (above 90 degrees); (2) drooping of lower rib-vertebra angles (below 90 degrees); and (3) linear rib growth being impaired relative to thoracic spinal growth in the lower ribcage (T6-12) of girls between childhood and puberty (Grivas et al. 1991 d). 5. The hypothesis is suggested that the relative narrowing of the lower chest with increasing age reduces the rotational inertia of the thorax in gait. There is a greater need for such reduction in girls because of the greater rotational inertia generated by the mass of their larger pelves. This hypothesis provides a mechanical explanation for the proportionate change in the girl's lung in the later stages of growth (Simon et al. 1972). 6. Developmentally, the left hemithorax is ahead of the right hemithorax in childhood. 7.
Thoracic
asymmetry favouring the right chest is found, and more so in puberty than childhood which is connected with the larger size of the thorax and lung in the adult. 8. The evidence suggests that hemithoracic development is caudocranial; this is consistent with an adaptation of the human ribcage to control spinal rotation and counterrotation when bipedal gait was acquired in evolution. 9. In progressive infantile idiopathic
scoliosis
, the upper chest is funnel-shaped.(ABSTRACT TRUNCATED AT 400 WORDS)
...
PMID:A segmental analysis of thoracic shape in chest radiographs of children. Changes related to spinal level, age, sex, side and significance for lung growth and scoliosis. 181 Sep 28
The incidence of thoracic
scoliosis
after completion of growth was studied in a group of patients operated on in childhood with a lateral thoracotomy for esophageal atresia and cardiac and pulmonary disorders. Twenty of 61 patients had a thoracic
scoliosis
exceeding 10 degrees. The curves were mostly convex toward the operated side except in patients treated surgically for esophageal atresia, in which they were concave toward the operated side. None of the curves exceeded 25 degrees, and no therapy was needed.
Thoracic
scoliosis
should, however, be remembered as a possible complication after lateral thoracotomy in childhood.
...
PMID:Thoracotomy and scoliosis. 194 3
Respiratory failure is the major cause of death in patients with Duchenne muscular dystrophy (DMD). In this report we retrospectively examined the clinical courses, pulmonary function, progression of
scoliosis
and the time of assisted ventilation. Forty nine patients, aged 2 to 27 years were studied and thirty eight patients of them were examined twice in some intervals. The subjects of examinations included pulmonary function studies consisting of spirometry, measurement of the thoracic
scoliosis
measured according to the method of Cobb and room air arterial blood gas values. The results were the following; 1) The decline in percentage values of vital capacity (%VC) began at age 8 or 9 and decreased consistently with age. Finally %VC reached under 10 percent at mean age of 21.53 with respiratory failure. 2)
Thoracic
scoliosis
measured according to the method of Cobb increased further with advancing age. The greater the angle of curvature, the more likely the development of respiratory failure. 3) Sixteen patients received negative pressure ventilator (chest respirator: CR) between 16.5 and 25.1 years of age. Twelve patients used part-time (mainly night-time) ventilator and four patients used it in full-time. The average PaCO2 and PaO2 before administration of ventilator were 67.49 mmHg and 71.46 mmHg, respectively. The levels after ventilation were 58.01 mmHg (PaCO2) and 82.09 mmHg (PaO2).
...
PMID:[Respiratory failure and its care in Duchenne muscular dystrophy]. 206 Feb 38
1
2
3
4
5
6
7
8
Next >>