Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0729233 (Thoracic)
 6,478 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Clinical stages of chronic obstructive pulmonary disease(COPD) have been described in the guideline by American Thoracic Society(ATS), European Respiratory Society(ERS), and Japanese Respiratory Society. Recently, the clinical stage in GOLD(Global Initiative Obstructive Lung Disease) was also published in the guideline as an international standard. Although severity or clinical stages of COPD in ATS, ERS, and JRS guidelines is determined by only % predicted FEV1.0/FVC(%FEV1.0), GOLD guideline added clinical symptoms to %FEV1.0 for determining clinical stages of COPD. Prognosis is also correlated with %FEV1.0 in COPD patients. Prognosis of COPD patients shows a clear decline in proportion to that of %FEV1.0. However, pulmonary circulation disorder also affects the prognosis of COPD. Pulmonary hypertension is often found in severe COPD.
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PMID:[Stage and prognosis of COPD]. 1467 15

Progressive non-malignant lung disease (PNMLD) is a common cause of morbidity and mortality in the UK. In 1999, chronic lung disease--including chronic obstructive pulmonary disease (COPD), tuberculosis, pulmonary circulatory disease, pneumonoconiosis, sarcoidosis and cystic fibrosis--killed almost 39,000 (British Thoracic Society, 2000), while it is estimated that 600,000 people in the UK have COPD, the most common non-malignant lung disease (BTS, 2001).
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PMID:Palliative care for people with end-stage non-malignant lung disease. 1573 98