Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0729233 (Thoracic)
 6,478 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Correctly performed antituberculous chemotherapy, together with the early diagnostics of tuberculosis, significantly lowered the need for surgery. Surgery is limited to patients with poor or no response to chemotherapy. In the period between 1983-1992 212 tuberculous patients were operated in the Clinic for Thoracic surgery, the Institute for the Pulmonary Disease the operated patients had the following form of the disease: primary tuberculosis in 4 patients (1.87%), 104 patients (49.06%) had the postprimary form of the disease, 67 patients (31.60%) had tuberculoma (causative lesion) cavernous tuberculosis existed in 33 patients (15.57%), while only 4 patients (1.87%) had diffuse pulmonary lesion. Diagnosis of post-tuberculous syndrome was made in 68 patients (32.08%). Secondary aspergylloma existed in 36 patients while the frequency of bronchial stenosis and bronchiectasis was the same -m 31 patients (16.98% and 14.63% respectively). One patient had broncho-oesophageal fistula. Tuberculous empiema, complicating the disease, existed in 36 patients (16.98%). Comparing the two 5-years periods, (1983-87 and 1988 to 1992) the authors conclude that the number of operations for tuberculosis is decreasing. Treatment was successful in all patients except in a patient with a broncho-esophageal fistula, who died postoperatively slow lung reexpansion existed in 5 patients, and in two cases partial upper thoracoplasty had to be done in order to solve the complication of the initial treatment. In all cases postoperative antituberculous chemotherapy was performed taking in consideration the problem of possible drug-resistance. There were no recurrences.
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PMID:[Modern surgical treatment of pulmonary tuberculosis]. 778 90

The clinical manifestations of thoracic tuberculosis are highly varied and unspecific, and can be superimposed on that of any other bacterial infection that affects the same organs. What is especially notable is the high frequency with which the primary infection goes unnoticed and the persistence of the symptomology in the secondary infection. This review analyses the most common signs and symptoms and the frequency of their presentation. Thoracic tuberculosis has a series of patterns of presentation and cure that, although equally varied and non-pathognomonic, are on occasion highly characteristic, with their discovery making possible a high level of diagnostic suspicion. We describe all the patterns of presentation of all the classically accepted primary and post-primary tuberculosis and their frequency, as well as the radiological characteristics of the most relevant complications and sequels.
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PMID:[Clinical manifestations and radiology of thoracic tuberculosis]. 1789 27