Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0729233 (Thoracic)
 6,478 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Long-term domiciliary ventilation is an effective treatment for chronic hypoventilation due to neuromuscular disease or thoracic deformity. As the majority of patients require assisted ventilation only at night, it is a simple means of improving quality of life, and even sometimes of prolonging life. According to a nationwide enquiry organised by the Swedish Thoracic Society in 1993, 460 patients (5.5 per 100,000 of the population) were using domiciliary ventilation (almost a doubling of the figure of 250 patients reported from a similar survey in 1990). The most prevalent indications were poliomyelitis sequelae (30%), followed by myopathy (21%), idiopathic scoliosis (13%) and tuberculosis sequelae (13%). Eighty per cent of the patients used assisted ventilation only at night, and 60 per cent used non-invasive devices such as a nasal mask.
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PMID:[Home respiratory therapy becomes more and more frequent. Increased quality of life via a simplified technique]. 770 Jan 13

Increasing numbers of patients are surviving episodes of prolonged mechanical ventilation or benefitting from the recent availability of userfriendly noninvasive ventilators. Although many publications pertaining to specific aspects of home mechanical ventilation (HMV) exist, very few comprehensive guidelines that bring together all of the current literature on patients at risk for or using mechanical ventilatory support are available. The Canadian Thoracic Society HMV Guideline Committee has reviewed the available English literature on topics related to HMV in adults, and completed a detailed guideline that will help standardize and improve the assessment and management of individuals requiring noninvasive or invasive HMV. The guideline provides a disease-specific review of illnesses including amyotrophic lateral sclerosis, spinal cord injury, muscular dystrophies, myotonic dystrophy, kyphoscoliosis, post-polio syndrome, central hypoventilation syndrome, obesity hypoventilation syndrome, and chronic obstructive pulmonary disease as well as important common themes such as airway clearance and the process of transition to home. The guidelines have been extensively reviewed by international experts, allied health professionals and target audiences. They will be updated on a regular basis to incorporate any new information.
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PMID:Home mechanical ventilation: a Canadian Thoracic Society clinical practice guideline. 2205 78