Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0729233 (Thoracic)
 6,478 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A five-month-old male Great Dane dog was clinically diagnosed as having a complex cardiac anomaly, including anomalous drainage of pulmonary veins. Thoracic radiographs were indicative of this condition, but cineangiocardiography was required for confirmation. At necropsy, examination of the heart revealed that all pulmonary veins entered the right atrium rather than the left atrium as in a normal animal. In addition, a large ostium secundum-type interatrial septal defect and stenosis of the pulmonic valve were demonstrated.
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PMID:Anomalous pulmonary venous return in a Great Dane. 111 90

A six-week-old male puppy was presented with a distended abdomen, dypsnoea and cyanosis. Auscultation revealed a grade II/VI systolic murmur. Thoracic radiographs showed gross cardiomegaly. An electrocardiogram revealed a narrow-complex tachycardia, deep S waves in leads I, II, III and aVF, and negative P waves in lead III. Two-dimensional echocardiography showed a high ventricular septal defect and marked dilation of the right-sided chambers. There was also an echolucent structure lateral to the left atrium at a site corresponding to the coronary sinus. Contrast echocardiography revealed right-to-left shunting through the septal defect. Necropsy confirmed the existence of a septal defect in the membranous part of the septum and a persistent left cranial vena cava with dilation of the coronary sinus. In addition, a small patent ductus arteriosus and tricuspid dysplasia were present.
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PMID:Persistent left cranial vena cava associated with multiple congenital anomalies in a six-week-old puppy. 940 13