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Query: UMLS:C0729233 (Thoracic)
 6,478 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In this article, based on a presentation before The Society of Thoracic Surgeons, D. Bruce Burlington, MD, director of the United States Food and Drug Administration's Center for Devices and Radiological Health, describes the role of the Center in regulating medical devices. Doctor Burlington discusses issues concerning investigational device exemptions and development of protocols, marketing review for new products, the use of guidance by the agency in developing products, and humanitarian device provisions. He focuses this discussion on circulatory support devices and therapies for cardiac patients. Throughout the discussion, Dr Burlington encourages manufacturers of new devices to discuss their plans and protocols with the agency before beginning their studies.
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PMID:FDA regulation of medical devices. FDA perspective. 856 34

An 11-year-old girl was admitted with back pain for 2 months, inability to walk for 15 days, and enuresis and encopresis for 2 days. She had been hospitalized with the diagnosis of brucellosis in another hospital. At presentation, she had paraplegia, sphincter dysfunction, and bilateral sensory loss below the T6 level, and was initially diagnosed with transverse myelitis caused by brucellosis. On the third day of hospitalization, however, agglutination test for brucella was negative, but it was positive for Salmonella. Therefore, transverse myelitis was considered to be due to salmonellosis. Thoracic spine magnetic resonance imaging showed an extradural, paraspinal mass at the level of T6-T7. The mass was totally extracted, and histopathological examination revealed Ewing's sarcoma. During follow-up, no improvement in paraplegia was noted and an enlarged presacral decubital ulcer developed. Aside from supportive care, local radiotherapy was applied. Unfortunately, the patient died from probable infection 9 months after the diagnosis. We emphasize that metastatic spinal Ewing's sarcoma may mimic brucellosis and transverse myelitis in childhood.
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PMID:A case of metastatic spinal Ewing's sarcoma misdiagnosed as brucellosis and transverse myelitis. 1476 89

Thomas Bruce Ferguson, the 12th president of The Society of Thoracic Surgeons, died surrounded by his family on May 26, 2013. He was a legendary figure in the world of cardiothoracic surgery. His visionary leadership was an inspiration to generations of cardiothoracic surgeons around the world.
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PMID:Thomas Bruce Ferguson, MD, May 6, 1923-May 26, 2013. 2469 40