Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0728731 (prematurity)
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Human Gene/Protein
SAPL 10.8
SEN34 10.5
GSTT2B 10.1
SLC27A4 9.5
EEFSEC 9.3
HLM-2 9.3
cysteine/histidine-rich 1 9.0
ABCA3 protein 8.8
SLC27A5 8.8
ALTE 8.4
FATP4 8.3
histone family member 8.3
VARS 8.2
Ermin 8.2
GATS 8.2
FREAC-1 8.1
TPSAB1 8.0
SP-A1 8.0
neuropeptide S receptor 1 7.9
Siglec-14 7.8
C16orf57 7.7
Thrombospondin-2 7.7
MRX34 7.7
very long-chain acyl-CoA synthetase 7.7
RDS 7.6
RLF 7.6
fatty acid transport protein 7.5
SLC12A1 7.5
Fumarylacetoacetate hydrolase 7.5
Leu-16 7.5
PKK2 7.4
Pregnancy-specific beta 1-glycoprotein 7.4
Myelin transcription factor 1 7.3
oxysterol 7alpha-hydroxylase 7.2
ALG12 7.1
SP-A2 7.1
Ca(2+)-transporting ATPase 7.1
C4BPA 7.1
PIPP 7.0
SERPINH1 7.0
ABHD12 6.8
SIDS 6.8
BREAST 6.8
mPR 6.8
AHCY 6.7
PNM 6.7
DLG4 6.6
M-ficolin 6.5
CRTAP 6.5
multidrug resistance protein 3 6.5
ADAMTS2 6.5
DGUOK 6.5
ABCA3 6.4
FATP 6.4
RagC 6.3
Citrin 6.3
Siglec-5 6.3
GP1BA 6.3
ZMPSTE24 6.3
NRG3 6.2
SLC26A3 6.2
SEH 6.2
KCNJ1 6.2
SPA1 6.2
EFTUD2 6.2
NPSR 6.2
ficolin-3 6.1
EPH 6.1
ARTS 6.1
antiquitin 6.1
IL1RAPL1 6.1
MPV17 6.0
OTOF 6.0
PNPO 6.0
CLCNKB 6.0
Epo receptor 6.0
5-oxoprolinase 6.0
ADK 5.9
Interleukin 18 5.9
IL-12A 5.9
more...
Disease
prematurity 12.1
Infantile hemiparesis 12.1
Neonatal nephrocalcinosis 12.1
Haemophilus sepsis 12.1
Homozygous alpha thalassaemia 12.1
Osteopenia of prematurity 11.4
Obstetric shock 11.1
Parotid abscess 11.1
Other anaemias 11.1
fetal neoplasm 11.1
Hypokalemic hypochloremic metabolic alkalosis 11.1
Neonatal chlamydial infection 10.5
Delayed delivery 10.5
Transient hypothyroxinemia 10.1
threatened labor 10.1
Tuberculosis in pregnancy 10.1
Listeria septicemia 10.1
Lactobezoar 10.1
Rotaviral infections 10.1
Acute otitis media with effusion 10.1
Congenital hyperthyroidism 9.8
Paroxysmal ventricular tachycardia 9.8
Congenital pneumonia 9.8
Recurrent apnea 9.5
Postnatal infection 9.5
CNS candidiasis 9.5
infantile apnea 9.4
Neonatal anemia 9.3
Glomerulonephropathy 9.3
Chronic lung disease 9.2
Enterococcal meningitis 9.1
Postoperative stricture 9.1
Neonatal listeriosis 9.1
Gallbladder sludge 9.0
Neonatal necrotizing enterocolitis 9.0
localized skin infection 9.0
ABO isoimmunization 9.0
Congenital diaphragmatic eventration 9.0
Metabolic bone disease 8.9
postmaturity 8.8
bronchopulmonary dysplasia 8.7
Cross syndrome 8.7
Benign neonatal sleep myoclonus 8.5
5-Oxoprolinuria 8.5
Anemia of prematurity 8.5
hyaline membrane disease 8.5
Periventricular leukomalacia 8.5
Wilson-Mikity syndrome 8.5
Hypertension complicated 8.4
Iatrogenesis 8.4
Cricopharyngeal achalasia 8.4
Anemia during pregnancy 8.4
Bone Dysplasia 8.4
premature rupture of membranes 8.4
Neonatal hyperthyroidism 8.3
Hemorrhagic disease of the newborn 8.3
Neonatal anoxia 8.3
Neonatal hypocalcemia 8.3
Sacrococcygeal teratoma 8.3
Fetal acidosis 8.2
LIH 8.2
chorioamnionitis 8.2
premature labor 8.2
necrotizing enterocolitis 8.1
Neonatal sepsis 8.1
Neonatal respiratory distress syndrome 8.1
Chlamydia trachomatis pneumonia 8.1
abruptio placentae 8.1
Acute viral bronchiolitis 8.1
caffeine abuse 8.1
Amnionitis 8.1
Embryopathy 8.1
NOMID 8.1
cervical incompetence 8.1
retinopathy of prematurity 8.0
Transient proteinuria 8.0
Klebsiella bacteremia 8.0
Neonatal meningitis 8.0
urinary tract infection during pregnancy 8.0
Cyanotic congenital heart disease 8.0
more...
Symptom
Pruritus of pregnancy 11.5
Poor weight gain 9.1
KIDNEY 8.1
Very Low Birth Weight 8.0
Bilious vomiting 8.0
Fetal tachycardia 7.5
false labor 7.5
Other pain 7.4
abnormal taste 7.2
stomach distension 6.8
delayed language development 6.7
bigeminal 6.7
Periodic breathing 6.6
Reticulocytosis 6.5
Darier's sign 6.5
respiratory distress 6.4
athetosis 6.1
hyperemesis gravidarum 5.8
hyperoxia 5.7
Flare 5.7
wheezing 5.6
trigeminy 5.5
tachypnea 5.5
monoplegia 5.3
nocturnal cough 5.3
iliac fossa pain 4.8
No adverse effect 4.8
cyanosis 4.8
Anoxia 4.6
Neurologic symptoms 4.6
labored breathing 4.4
tonic seizure 4.4
microbial colonization 4.4
torticollis 4.3
hypercapnia 4.1
Catch 4.1
stridor 4.1
lassitude 4.0
hyperemesis 3.9
neurological disability 3.9
rales 3.8
Psychiatric symptoms 3.8
hypotonia 3.8
pallor 3.6
oliguria 3.6
hypothermia 3.5
hypertonia 3.4
spasticity 3.4
rhinorrhea 3.3
lethargy 3.2
polyuria 3.1
enuresis 3.0
retching 3.0
ketonuria 3.0
hypocapnia 3.0
adenitis 3.0
hypoproteinemia 3.0
persistent cough 2.9
dysuria 2.9
colic 2.8
Mills 2.8
drooling 2.7
leg pain 2.7
hepatomegaly 2.6
clonus 2.6
cough 2.6
physical appearance 2.5
seizures 2.5
renal colic 2.5
epigastric pain 2.4
hepatosplenomegaly 2.3
incoordination 2.3
clubbing 2.3
vomiting 2.3
regurgitation 2.3
hoarseness 2.2
diarrhea 2.1
tense 2.0
splenomegaly 2.0
abnormal gait 2.0
more...
Drug
Colfosceril palmitate 12.1
Lucinactant 9.1
Dopram 8.8
Dalacin 8.5
Doxapram 8.5
Indecainide 8.4
Palivizumab 8.3
Tranexamic Acid 7.9
anti-RSV 7.3
Prepidil 7.2
Epostane 6.9
Magnesium sulfate 6.9
Atosiban 6.9
Dalacin 6.9
Pleconaril 6.8
Visken 6.7
Survanta 6.7
Domin 6.7
Imferon 6.4
Meconium 6.3
Vibramycin 5.9
Ceftibuten 5.7
Ovulen 5.6
Syntocinon 5.5
Sinemet 5.4
Spiegel 5.3
Theophylline 5.1
Meditec 5.0
Sulphasalazine 4.9
Epoetin alfa 4.9
Methyldopa 4.8
Eculizumab 4.7
Inderal 4.6
caffeine 4.6
Lipidex 4.5
Epoetin alfa 4.5
Ethane 4.4
Ipratropium bromide 4.4
Fenoterol 4.2
Tubocurarine 4.2
Epoetin 4.0
IPD 3.9
Fluconazole 3.8
Modafinil 3.5
Lugol 3.5
Doyle 3.5
Rolipram 3.4
APD 3.3
CVA 3.2
Prednisone 3.1
AmBisome 3.1
Salbutamol 3.1
Neoral 3.1
Triclosan 3.1
LMWH 3.1
Dakar 3.1
ampicillin 2.9
Vitamin A 2.9
Hypaque 2.9
Indomethacin 2.8
Everolimus 2.7
Tocopherol 2.7
Vitamin K 2.7
OTC 2.6
Ganciclovir 2.6
vitamin E 2.5
Pravastatin 2.5
Vitamin E 2.4
CPR 2.4
Atenolol 2.4
Alliance 2.3
Gastro 2.3
DDAVP 2.2
DDAVP 2.2
Bifidobacterium 2.2
CTC 2.1
OTC 2.1
IL-11 2.0
Infliximab 2.0
Infliximab 2.0
more...
Enzyme
PdxH 6.4
C5a peptidase 5.9
5-oxoprolinase 5.7
phosphatidylglycerophosphate synthase 5.5
PRT 5.3
sulfiredoxin 5.1
guanidinoacetate methyltransferase 5.0
glycine N-methyltransferase 4.8
glycine amidinotransferase 4.8
ScpA 4.7
adenylosuccinate lyase 4.6
valyl-tRNA synthetase 4.5
AOR 4.5
phosphocholine cytidylyltransferase 4.4
PPH 4.2
lysophosphatidylcholine acyltransferase 4.1
acyl-CoA synthetase 4.0
fumarylacetoacetate hydrolase 4.0
EPT 3.9
p100 3.9
3-hydroxyacyl-CoA dehydrogenase 3.7
3-hydroxyacyl-CoA dehydrogenase 3.7
methionine adenosyltransferase 3.7
phospholipase A1 3.5
argininosuccinate lyase 3.4
choline kinase 3.3
meprin 3.0
CDH 3.0
lecithin:cholesterol acyltransferase 2.9
acyl-CoA synthetase 2.8
glutathione synthetase 2.7
monoacylglycerol lipase 2.7
argininosuccinate synthetase 2.7
type III procollagen 2.7
methylenetetrahydrofolate reductase 2.7
methylenetetrahydrofolate reductase 2.6
gamma-glutamylcysteine synthetase 2.6
ornithine aminotransferase 2.6
SST 2.6
GABA transaminase 2.5
ceruloplasmin 2.4
12-lipoxygenase 2.4
ferrochelatase 2.3
prostaglandin synthetase 2.3
adenosine kinase 2.3
BIS 2.2
glucokinase 2.2
thioredoxin reductase 1.9
PDE 1.9
phenylalanine hydroxylase 1.7
PGM 1.7
acyl-CoA dehydrogenase 1.6
TOR 1.6
MAT 1.6
glucose-6-phosphate dehydrogenase 1.5
leucine aminopeptidase 1.5
ornithine transcarbamylase 1.4
MAT 1.4
tryptophan hydroxylase 1.3
alkaline phosphatase 1.3
renin 1.2
cholesterol acyltransferase 1.1
ADH 1.0
gamma-glutamyl transpeptidase 1.0
elastase 1.0
diamine oxidase 0.9
MAP 0.9
CDR 0.8
CPR 0.8
collagenase 0.8
thromboplastin 0.7
MDP 0.7
sialidase 0.7
myosin light chain kinase 0.7
tryptase 0.7
tissue plasminogen activator 0.7
phospholipase A2 0.6
acetyl-CoA carboxylase 0.6
plasmin 0.6
AST 0.6
more...
Compound
Dopram 8.8
Methylxanthine 8.8
HPLA 8.1
1-hydrazinophthalazine 7.2
Magnesium sulfate 6.8
Magnesium sulfate 6.7
Ritodrine 6.6
Pinitol 6.4
Betamethasone 6.3
beta-BHC 6.0
Phloroglucinol 6.0
Ceftibuten 5.9
PNB 5.9
Phloroglucinol 5.9
PIH 5.8
Disopyramide 5.7
N'-methylnicotinamide 5.7
OLN 5.4
Diatrizoate 5.4
Maltodextrin 5.4
Diatrizoate 5.4
17-OHP 5.3
Zinc protoporphyrin 5.2
3-methylcrotonyl-CoA 5.2
4-hydroxyphenylpyruvate 5.1
Heroin 5.1
Prone 5.1
Theophylline 5.0
Procainamide 5.0
Practolol 4.8
PDP 4.8
Parenteral 4.7
caffeine 4.6
5-oxoproline 4.6
5-oxoproline 4.6
Benznidazole 4.5
Benznidazole 4.5
Benznidazole 4.5
Tauroursodeoxycholic acid 4.4
5-oxoproline 4.4
Tubocurarine 4.3
EOS 4.3
Hydroxychloroquine 4.2
Cabergoline 4.2
VMA 4.1
S 1 4.1
Aminophylline 4.1
IAS 4.0
5-oxoproline 4.0
5-HETE 4.0
Nitrofurantoin 4.0
IPD 3.9
Calcium carbonate 3.9
Thiopental 3.9
Thyroxine 3.9
Ursodeoxycholic acid 3.9
Akron 3.9
PRN 3.9
Nevirapine 3.8
Sulindac 3.8
Creatine 3.7
Vigabatrin 3.6
Xanthine 3.6
Metyrapone 3.6
DBM 3.6
Erythromycin 3.6
Metyrapone 3.6
DBM 3.6
NMA 3.6
Pyridoxine 3.6
Terbutaline 3.5
Epirubicin 3.5
Sotalol 3.5
AIR 3.5
PHE 3.5
Docosahexaenoic acid 3.4
HCA 3.4
Cystine 3.4
cyclopentanone 3.4
cyclopentanone 3.4
more...