Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0728731 (prematurity)
7,134 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Since the obstetrician has the first opportunity to influence the mother, he should be knowledgeable about breast-feeding. Prenatal preparation, discussion of fears and anxieties, and the provision of literature are outlined as elements of successful nursing. The anatomy and physiology of nursing include a discussion in lay terms of milk production and milk ejection (let down), nipple examination, nursing posture, simulated nursing technique, breast massage and manual expression. Elements of nursing during hospital stay discussed are parturition, the nursing staff, jack-nifing the infant in preparation for feeding, breaking suction, feeding schedule, milk tension, foremilk, ejection reflex and the formation of hindmilk, aids in milk ejection, frequency and length of feedings, the use of both breasts, the draught, demand feeding and rooming in, dehydration, brassiere, uterine cramps, sore nipples, prematurity, cesarean section, and multiple births. Infant requirements, jaundice, postpartum examination, stools, colic, rashes, medication, contraception, bottle-feeding, maternal diet, fatigue and stress, leaking, the working mother, solid foods, breast infection and weaning are discussed as a part of the posthospital period.
...
PMID:The obstetrician's approach to the breasts and breastfeeding. 112 77

The temperament of a group of preterm infants (n = 126) was studied as part of a large, longitudinal study of infant temperament and behavior in a representative sample of Australian infants (n = 2443). Utilizing the Infant Temperament Questionnaire of Carey and McDevitt, previously revised and validated for an Australian population, ratings were made at 4 to 8 months corrected age, and data for the preterm group (less than 37 weeks gestation) were compared to those infants born at term (37 to 41 weeks). There were no significant differences between the two groups on any of the sociodemographic variables, on the mother's global rating of temperament, or on the reported incidence of colic, sleep problems, and excessive crying. There were also no differences between premature and full-term infants on any of the individual dimensions or clinical categories of temperament. We conclude that prematurity per se does not affect observed temperament at 4 to 8 months. However, we cannot extend these conclusions to high-risk infants who experience medical complications of prematurity, and who require intensive care for prolonged periods of time. These may represent an entirely different category of risk for subsequent difficult temperament and behavior problems.
...
PMID:Temperament of preterm versus full-term infants. 372 91

The relative influence of early life events in the development of IgE-mediated allergy is still undetermined. We investigated early life factors in relation to skin-prick test positivity (SPT) and clinical manifestations of atopic disease in a population-based sample of 201 Italian children (3 months-5 years), after considering their interactions with known determinants of allergy. Among them, 143 children had SPT performed to common allergens. Threatened abortions, general anesthesia at delivery, prematurity, birthweight < 2500 g, maternal smoking, dampness and gas heating exposure were all significantly related to an increased risk of frequent rhinitis in the absence of cold (18%). In utero smoking, threatened abortions, fetal health complications, infantile colic, maternal smoking in childhood (satisfactorily correlated with maternal expired CO during the survey) and respiratory infections were all independent determinants of frequent wheezing (23%). Doctor's diagnosis of asthma (3%) was related to in utero smoking, being born in spring, infantile colic and respiratory infections. A simultaneous exposure to in utero smoking and infantile colic put the infants to a fourfold higher risk of frequent wheezing and to a ninefold risk of asthma, respectively. Having a pet and washing blankets at < 60 degrees C were inversely related to frequent wheezing. Data confirmed also that maternal phenotype influences the inheritance of atopic disease. No event, except a low intake of fruit (< 3/week), was significantly associated with positive SPT (20%) or eczema. Besides allergic sensitization, other events, which occur early in life, seem critical to the development of IgE-mediated allergy.
...
PMID:Early life factors related to clinical manifestations of atopic disease but not to skin-prick test positivity in young children. 1200 Apr 82

Diagnostic imaging can substantially augment physical examination findings in neonatal foals. Used in combination with radiography or as a stand-alone imaging modality, ultrasound evaluation of the thoracic and abdominal body cavities can be a high-yield diagnostic undertaking. Many of the conditions that afflict neonatal foals are highly amenable to sonographic interrogation, including pneumonia and other changes in the lungs associated with sepsis, systemic inflammatory response syndrome, multiple organ dysfunction, and prematurity; colic arising from medical and surgical causes; and urinary tract disorders. Sonographic imaging is not affected by intracavitary fluid accumulation and reveals abnormalities of soft tissue and bony origin.
...
PMID:Ultrasonographic Examination of the Equine Neonate: Thorax and Abdomen. 2661 46

Recent studies have highlighted the fact that the enteric microbiome, the trillions of microbes that inhabit the human digestive tract, has a significant effect on health and disease. Methods for manipulating the enteric microbiome, particularly through probiotics and microbial ecosystem transplantation, have undergone some study in clinical trials. We review some of the evidence for microbiome alteration in relation to childhood disease and discuss the clinical trials that have examined the manipulation of the microbiome in an effort to prevent or treat childhood disease with a primary focus on probiotics, prebiotics, and/or synbiotics (ie, probiotics + prebiotics). Studies show that alterations in the microbiome may be a consequence of events occurring during infancy and/or childhood such as prematurity, C-sections, and nosocomial infections. In addition, certain childhood diseases have been associated with microbiome alterations, namely necrotizing enterocolitis, infantile colic, asthma, atopic disease, gastrointestinal disease, diabetes, malnutrition, mood/anxiety disorders, and autism spectrum disorders. Treatment studies suggest that probiotics are potentially protective against the development of some of these diseases. Timing and duration of treatment, the optimal probiotic strain(s), and factors that may alter the composition and function of the microbiome are still in need of further research. Other treatments such as prebiotics, fecal microbial transplantation, and antibiotics have limited evidence. Future translational work, in vitro models, long-term and follow-up studies, and guidelines for the composition and viability of probiotic and microbial therapies need to be developed. Overall, there is promising evidence that manipulating the microbiome with probiotics early in life can help prevent or reduce the severity of some childhood diseases, but further research is needed to elucidate biological mechanisms and determine optimal treatments.
...
PMID:The Significance of the Enteric Microbiome on the Development of Childhood Disease: A Review of Prebiotic and Probiotic Therapies in Disorders of Childhood. 2777 1