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Query: UMLS:C0728731 (prematurity)
 7,134 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Six month infant-mother interaction patterns were observed and 10 month Bayley MDI scores were obtained in 10 fullterm and 14 healthy preterm (less than 37 weeks) infants. Relationships among interaction parameters and intellectual performance are compared with those among earlier interaction patterns and development. At 6 months preterm dyads were more synchronised and had higher levels of interaction than fullterm dyads; preterm mothers demonstrated lower levels of affection. Fullterm variables reflecting unfocussed infant vocalising at 2, 3 and 6 months were negatively related to later development while those maternal variables indicating general and specific stimulation were positively related. Preterm infant vocalising levels at 3 and 6 months were positively related while 3 and particularly 6 month variables indicating maternal stimulation and high levels of dyadic interaction were negatively related to later development. In both groups early maternal state differentiation in responses was positively related to 10 month intellectual performance. Ten month MDI scores for the preterm group were lower than for the fullterm group. The results are discussed with respect to information processing abilities, optimal patterns of interaction for each kind of infant, and their differential paths of development in the first year.
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PMID:Interaction and development in the first year. I. The effects of prematurity. 370

Maternal cocaine use during pregnancy can affect the infant directly through toxic effects or indirectly through cocaine's influence on maternal psychological status. We followed 160 cocaine exposed and 56 nonexposed infants and their mothers identified at birth through interview and/or urine screen. Although cocaine exposure defined the groups, infant exposure to alcohol, marijuana, and tobacco was allowed to vary. Infants were 99% African American and poor. All mothers completed the Brief Symptom Inventory (BSI) and infants were given the Bayley Scales of Mental (MDI) and Motor (PDI) Development at a mean corrected age of 17 +/- 8 months. Both MDIs (94 +/- 17 vs. 103 +/- 16) and PDIs (101 +/- 16 vs. 108 +/- 12) were lower for cocaine exposed infants. Psychological distress was greater in cocaine using mothers. Hierarchical multiple regression was used to assess the relative effects of gestational age, maternal psychological distress, and cocaine and polydrug exposure on infant outcomes. Both psychological distress and cocaine and alcohol exposure predicted lower MDIs after controlling for prematurity. Neither psychological distress nor alcohol exposure predicted motor outcome, while cocaine had a significant effect. Tobacco and marijuana exposure were unrelated to outcome. These findings provide further support for direct effects of cocaine and alcohol on infant development as well as highlight the need for studies to document maternal psychological factors, which may increase child risk for poorer outcomes.
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PMID:Relationship of prenatal cocaine exposure and maternal postpartum psychological distress to child developmental outcome. 932 34