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Query: UMLS:C0728731 (prematurity)
 7,134 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In 152 amniotic fluid samples, derived either from amniocentesis or amniotomy, smears have been performed for cytological investigation (staining after Harris-Shorr). The per cent amount of different cell-shapes has been determined. Polygonal, anucleate, transparent cells, representing desquameted fetal keratinocytes, are seen more frequently in late pregnancy and have been registered separately. These data have been compared to the postnatal determination of gestational age after Dubowitz et al, as well as Farr et al. This mode of investigation allows a safe and objective determination of maturity in the last weeks of pregnancy and thereby an exclusion of a presumed fetal prematurity. This method seems very useful in differential diagnosis between fetal hypotrophy and prematurity in the latter part of pregnancy.
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PMID:[Antenatal estimation of fetal maturity by exfoliative cytology of amniotic fluid (author's transl)]. 57 51

Current methods for estimating gestational age using clinical parameters can be inaccurate in prematurity. A simplified ultrasonographic system, based on cerebral sulcal development, for clinically determining fetal maturation in newborns was developed and studied in 148 newborns (92 appropriate-for-gestational-age, 54 small-for-gestational-age and 2 large-for-gestational age). This ultrasonographic sulcal method correlates better with the gestational age by dates than by the Dubowitz scoring system in the neonates less than 30 weeks' gestation. There are significant correlations between gestational age assessed by dates and by sonographic sulcal age in both appropriate-for-gestational-age (R = 0.91, P less than 0.001) and small-for-gestational-age newborns (R = 0.92, P less than 0.001). Maternal hypertension during pregnancy is a significant risk factor associated with accelerated fetal cerebral maturation in 12 neonates. Although overestimate of gestational age may occur in neonates born to mothers with hypertension, cranial ultrasonography is an accurate and convenient method of estimating gestational age in neonates.
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PMID:Assessment of gestational age in newborns by neurosonography. 193 42

Heavy maternal workloads are considered to be hazardous to the fetus. The effects of physical activity during pregnancy on low birth weight (LBW), small for gestational age (SGA), and prematurity were assessed from a sample of 1797 women in a follow-up study at the antenatal clinic of two hospitals in southern Thailand. The women were interviewed twice, at 17 and 32 gestational weeks. Outcome data were obtained from medical records and the newborn gestational age determined using Dubowitz's score. The risk of SGA was elevated for women working > 50 hours/week, squatting in work, commuting > 1 hour/day, and having high psychological job demands; the risk of preterm delivery was increased with obstetrical complications. Women who worked long hours and had demanding work conditions had an elevated risk of giving birth to SGA infants but not of preterm delivery.
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PMID:The effect of heavy maternal workload on fetal growth retardation and preterm delivery. A study among southern Thai women. 983 Jun 10

Mate, a hot infusion of Ilex paraguayensis, is a beverage largely consumed in Southeast Latin America, including during pregnancy. To assess the effect of mate drinking during pregnancy on preterm and small for gestational age (SGA) birth, a cross-sectional study was done. From January 1st to December 31st, 1993, in the first 24 h after delivery, all 5304 mothers giving birth at the hospitals in Pelotas, Southern Brazil, were interviewed and several of their characteristics were gathered. Birthweight was recorded and gestational age at birth assessed using the Dubowitz score. All 5189 single births were analyzed. The prevalence of SGA and preterm birth was 8.0 and 9.1%, respectively. Mate intake at least once a week during the entire pregnancy period was reported by approximately 68% of the mothers. Crude analyses showed a 30% increase in the risk of SGA among daily mate drinkers compared with nonconsumers (prevalence ratio = 1.3; 95% CI 1.1-1.6), whereas no statistical association was detected with preterm births. After controlling for confounders, the significance of the association with SGA birth no longer held and the lack of association with prematurity remained unchanged. In conclusion, prevalence of daily mate drinking was high among pregnant women and, contrary to the hypothesis, no harmful effect on intrauterine growth or duration of pregnancy was detected.
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PMID:Mate drinking during pregnancy and risk of preterm and small for gestational age birth. 1586 91

Newborns in Behira governorate represented 2.5% of total Behira population in 2000. In Damanhour teaching hospital 4040 live births were delivered during one year from 1st January 1995 to 31st December 1995. During this period an observational study of morbidity and mortality of the newborn unit (NBU) attendants was performed. The total number of admitted neonates to the newborn unit were 557, of those 307 were borne in hospital (representing 7.6% of total hospital deliveries) and 250 were admitted from outside the hospital. The number of eligible neonates for the study were 544, they spent 2355 days in the unit, thirteen neonates were excluded from the analysis. The low birth weight (< 2500 gm) were 218 (40% of studied cases). According to Dubowitz score, Infants were classified as appropriate for gestational age (AGA) 60.7%, small for gestational age (SGA) 27.6% and large for gestational age (LGA) 11.8%. Neonates with birth weight < 1500 gm and gestational age < 28 weeks had the worst prognosis with a mortality rate of 60.3% and 65.1% respectively. All neonates had 738 morbid conditions, the major causes were prematurity 262 (35.5%), respiratory distress (RD) 200 (27%) hyperbilirubinaemia 115 (15.6%) and sepsis 58 (7.9%). Most of the cases (73.9%) were admitted on the day of birth. The mortality rate was 28.5%. The leading causes of mortality were, RD ( 34.8% of all deaths), prematurity (32.9%) and sepsis (15.5%). Neonatal convulsions and congenital anomalies had highest case fatality rates (50% for each). Most of deaths (51%) occurred on the first day of admission. "The early results of this work was presented at the 6th international conference of the General Organization of "Teaching Hospitals and Institutes (GOTHI) "Health Services..... Present and future" 7-9 November 2001".
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PMID:A study of neonatal morbidity and mortality at Damanhour Teaching Hospital Newborn Unit. 1726 8