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7,134 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Blood pressure screening is an important component of the pediatric outpatient visit. The following case describes a 9-year-old male with a medical history significant for prematurity, obesity, asthma, and secondary nighttime enuresis who was admitted to our institution with hypertensive urgency. His blood pressure on presentation was 166/122 mm Hg, and he was clinically asymptomatic. There is a strong family history of hypertension, renal disease, and brain cancer. During his admission, his blood pressures were medically managed. He received a comprehensive diagnostic investigation of possible primary or secondary causes of hypertension, including consultation with nephrology, endocrinology, and ophthalmology subspecialty teams. The etiology of the hypertension was determined, and he was subsequently treated for a rare and life-threatening disease. This case highlights the importance of the close surveillance of children with hypertension.
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PMID:A 9-year-old male with hypertension. 2562 28

Characterizing the neuroanatomical correlates of brain development is essential in understanding brain-behavior relationships and neurodevelopmental disorders. Advances in brain MRI acquisition protocols and image processing techniques have made it possible to detect and track with great precision anatomical brain development and pediatric neurologic disorders. In this chapter, we provide a brief overview of the modern neuroimaging techniques for pediatric brain development and review key normal brain development studies. Characteristic disorders affecting neurodevelopment in childhood, such as prematurity, attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), epilepsy, and brain cancer, and key neuroanatomical findings are described and then reviewed. Large datasets of typically developing children and children with various neurodevelopmental conditions are now being acquired to help provide the biomarkers of such impairments. While there are still several challenges in imaging brain structures specific to the pediatric populations, such as subject cooperation and tissues contrast variability, considerable imaging research is now being devoted to solving these problems and improving pediatric data analysis.
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PMID:Structural neuroimaging. 3297 82