Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0700208 (scoliosis)
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Human Gene/Protein
MYH7 protein 11.9
Hypothetical short protein 11.9
Galactose-3-O-sulfotransferase 4 11.9
26S protease regulatory subunit 8 11.9
TMEM184C 11.9
G protein-coupled receptor 126 11.6
Ras and Rab interactor 2 11.3
ladybird homeobox 1 11.3
SH3TC2 protein 10.9
fibrillin 15 10.9
olfactomedin-like 1 10.9
ZNF541 10.9
golgin, RAB6-interacting 10.9
p59 subunit 10.9
CMT4C 10.4
RIN2 10.4
LBX1 10.3
SH3TC2 10.2
ROBO3 10.1
TMEM51 9.9
AHNAK nucleoprotein 9.9
PIGK 9.9
TBX6 9.8
GZF1 9.5
Golgi UDP-GlcNAc transporter 9.5
chromodomain helicase DNA binding protein 2 9.5
kyphoscoliosis peptidase 9.5
DSTYK 9.5
CLCF1 9.4
MESP2 9.3
EXOC6B 9.3
horizontal gaze palsy with progressive scoliosis 9.3
Golgi SNAP 9.3
MEIS3 9.3
potassium inwardly-rectifying channel 9.3
regulating synaptic membrane exocytosis 2 9.3
GPR126 9.2
COL27A1 9.2
PPP1R9B 9.2
KLHL7 9.2
TUBGCP4 9.1
RIPPLY2 9.1
SEPN1 9.0
FGD4 8.9
PIGU 8.9
SEDC 8.9
SLC8A2 8.9
NXF5 8.9
GOSR2 8.9
Chondroadherin 8.7
MSTO1 8.7
ECEL1 8.7
TMBIM4 8.7
myosin light chain, phosphorylatable, fast skeletal muscle 8.7
SNRPB 8.7
DA2B 8.7
HYDIN2 8.7
IRX4 8.6
SEDT 8.5
STAC3 8.5
COL23A1 8.5
LFNG 8.5
KIAA1217 8.5
BNC2 8.4
MHC class 1 antigen 8.4
Spinocerebellar ataxia 7 8.4
MATN1 8.4
G protein-regulated inducer of neurite outgrowth 1 8.4
DHX34 8.4
calmodulin-binding transcription activator 1 8.3
GNB4 8.3
TELO2 8.3
PTDSS1 8.3
AIS 8.2
IRX2 8.2
RIMS2 8.2
ZC4H2 8.2
IER3IP1 8.2
BRWD3 8.2
Homeobox protein 8.1
more...
Disease
Scoliosis associated with other conditions 11.9
VACTERL ASSOCIATION 11.9
Horizontal gaze palsy 11.9
scoliosis 11.9
Infantile idiopathic scoliosis 11.9
Drug-induced diabetes mellitus 11.9
Postoperative pneumothorax 11.9
MURCS ASSOCIATION 11.9
Resolving infantile idiopathic scoliosis 11.9
Biconcave vertebrae 11.9
Neuromuscular scoliosis 11.5
Kyphosis and lordosis 11.4
CISS2 11.1
Neuropathic arthritis 10.9
Thoracolumbar scoliosis 10.9
CISS1 10.9
Man-in-the-barrel syndrome 10.9
BRKS2 10.9
BRKS1 10.9
Iliac vein thrombosis 10.9
partial monosomy 2q 10.9
CMT4C 10.8
Progression of rheumatoid arthritis 10.3
Miles-Carpenter syndrome 10.3
Peripheral sensorimotor neuropathy 10.3
Generalized osteopenia 10.3
Amyloid neuropathy 10.3
Sponastrime dysplasia 9.9
Localized tetanus 9.9
CMT1E 9.9
Hydrosyringomyelia 9.9
SPONASTRIME 9.9
osteoarthritis of the lumbar spine 9.9
Bruck syndrome 9.8
Progressive pulmonary hypertension 9.5
Esophageal atresia/tracheoesophageal fistula 9.5
acrorenal syndrome 9.5
Multiple joint contractures 9.5
Choanal stenosis 9.5
Scheuermann's disease 9.5
Protrusio acetabuli 9.5
arachnodactyly 9.4
Scapuloperoneal spinal muscular atrophy 9.3
recombinant 8 syndrome 9.3
diploid/triploid mixoploidy 9.3
Staphylococcus epidermidis meningitis 9.3
labile personality 9.3
CMT2B1 9.3
Congenital fiber type disproportion 9.2
diastematomyelia 9.1
IS1 9.1
XLAG 9.1
Linear and whorled nevoid hypermelanosis 9.1
Wilms' tumor stage 9.1
Distal arthrogryposis 9.1
ring chromosome 12 9.1
Hepatic osteodystrophy 9.1
de Barsy syndrome 9.1
Neuhauser syndrome 9.0
LQT7 8.9
spondyloperipheral dysplasia 8.9
DA7 8.7
14q deletion syndrome 8.7
CMT2B2 8.7
protruded disk 8.7
Restrictive lung disease 8.7
Marshall-Smith syndrome 8.6
spondylolisthesis 8.6
Vertebral column 8.5
tetrasomy 15q 8.5
trisomy 19q 8.5
Bronchial compression 8.5
Vertebral column 8.5
CACP 8.5
Spinal instability 8.5
facet joint degeneration 8.5
flatback syndrome 8.4
uniparental disomy of chromosome 14 8.4
Jarcho-Levin syndrome 8.4
Proteus syndrome 8.3
more...
Symptom
Generalized fatigue 9.3
poor balance and coordination 9.3
musculoskeletal back pain 9.3
Antecollis 9.1
Tandem gait 8.5
chest restriction 8.5
Easy bruising 8.4
prominent nose 8.3
hypertrophic breast 8.3
Night pain 8.3
Persistent vomiting 8.2
Neurogenic pain 8.0
Sensory ataxia 7.8
Lasegue's sign 7.8
Ankle stiffness 7.7
Quadriceps weakness 7.5
rib pain 7.4
lumbar instability 7.4
iridodonesis 7.3
Pyramidal signs 7.3
Poor weight gain 7.2
torticollis 7.2
thoracic back pain 7.1
Halo 6.9
Q angle 6.8
finger pain 6.6
delayed language development 6.4
lumbar back pain 6.4
hypotonia 6.4
Radicular pain 6.4
Plantar flexion 6.2
back pain 6.2
leg pain 6.2
Central pain 6.2
Referred pain 6.1
coccygodynia 6.1
monoplegia 6.1
abnormal reflex 6.1
distraction 5.9
Joint hypermobility 5.9
Organ failure 5.9
nerve root irritation 5.9
Spontaneous nystagmus 5.9
abnormal breathing 5.7
paraparesis 5.6
abiotrophy 5.5
Lhermitte's sign 5.5
abnormal gait 5.4
athetosis 5.4
spasticity 5.4
low back pain 5.4
Spastic 5.4
loss of balance 5.4
ataxic gait 5.3
sighing 5.3
growing pains 5.2
Buckling 5.2
hypertonia 5.2
chronic back pain 5.1
cardiovascular impairment 5.1
Platypnea 5.1
weakness 5.0
female puberty 4.9
thigh pain 4.8
drooling 4.8
physical appearance 4.7
sciatica 4.6
ophthalmoplegia 4.5
Severe pain 4.5
Physical findings 4.5
Catch 4.4
scaly skin 4.4
hypalgesia 4.4
hyperesthesia 4.4
Postoperative pain 4.4
pachyonychia 4.3
Regurgitation 4.3
arm weakness 4.3
clonus 4.3
neck pain 4.2
more...
Drug
Deflazacort 8.1
Arfonad 6.9
Somatropin 6.3
Arfonad 6.3
CXM 6.2
Sulla 5.9
Triptorelin 5.6
TMX 5.6
Cobalamin 4.8
Metrizamide 4.7
Conray 4.4
Growth hormone 4.2
Growth hormone 4.2
Thiopentone 4.2
Aprotinin 4.0
CTM 3.9
Desferal 3.9
Zmax 3.8
Desferal 3.8
TES 3.7
Premarin 3.6
CPO 3.6
EDR 3.5
CTM 3.5
Dexon 3.5
Posture 3.5
Teriparatide 3.5
Frontal 3.4
Piracetam 3.4
Zinat 3.3
MTC 2.9
AIC 2.8
Propofol 2.8
Vicryl 2.8
GHRP 2.7
BTC 2.7
Azithromycin 2.6
Vitamin B12 2.6
Glide 2.6
Fentanyl 2.5
Depo-Provera 2.5
CAM 2.3
Gelfoam 2.3
Clonidine 2.2
Ceftazidime 2.2
PTC 2.1
DDAVP 2.0
Isoniazid 1.9
DDAVP 1.9
Check 1.9
Salbutamol 1.8
CTC 1.8
Horizon 1.6
Serum albumin 1.6
Vitamin B 1.6
DPA 1.5
CTC 1.5
NBT 1.5
CTA 1.4
Prednisolone 1.3
Monit 1.3
Bayer 1.2
TAC 1.2
CPR 1.1
Award 1.1
Norplant 1.1
nitroglycerin 1.1
TTC 1.0
CSF 0.9
Spectrum 0.9
Dakar 0.8
Paraffin 0.8
Fragment 0.7
Adriamycin 0.7
Spectrum 0.5
Ringer's solution 0.4
Mutagen 0.3
AZT 0.3
Leaf 0.3
Retinoic acid 0.1
more...
Enzyme
PHOSPHO1 8.0
lysyl hydroxylase 6.2
DSR 6.0
galactosyltransferase I 5.7
coagulation factor VIIa 5.2
hatching enzyme 4.8
CTD kinase 4.7
CAO 4.4
CDH 4.3
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.2
GM3 synthase 4.1
esterase D 3.9
pantothenate kinase 3.9
proline oxidase 3.8
PME 3.3
nucleotide pyrophosphatase 3.3
rhodopsin kinase 3.3
transaldolase 3.2
methylmalonyl-CoA mutase 3.2
chymopapain 3.2
chymopapain 3.1
cyclohydrolase 3.1
CAD 3.1
CAD 3.1
CAD 3.0
BIS 3.0
TGT 2.9
nucleotidase 2.9
MMP-3 2.7
myosin ATPase 2.7
lysyl oxidase 2.6
endothelin-converting enzyme 2.5
DAT 2.3
MCS 2.3
acyl-CoA dehydrogenase 2.2
ubiquitin-protein ligase 2.2
methionine synthase 2.2
PHD 2.1
methionine synthase 2.0
cathepsin K 2.0
Rex 2.0
creatine kinase 2.0
ECH 1.8
proprotein convertase 1.8
fumarase 1.7
acyl-CoA dehydrogenase 1.4
alpha-mannosidase 1.3
triphosphatase 1.3
sialyltransferase 1.3
apyrase 1.3
sialyltransferase 1.3
sialyltransferase 1.3
succinic dehydrogenase 1.1
glycerol-3-phosphate dehydrogenase 1.1
AOR 1.1
glycerol-3-phosphate dehydrogenase 1.0
prolyl hydroxylase 1.0
DCF 0.9
alkaline phosphatase 0.8
methylenetetrahydrofolate reductase 0.8
methylenetetrahydrofolate reductase 0.8
phosphoglycerate kinase 0.8
matrix metalloproteinase 9 0.8
citrate synthase 0.7
thromboplastin 0.5
MDP 0.5
succinate dehydrogenase 0.4
phosphorylase 0.4
pepsin 0.4
carboxylesterase 0.3
isocitrate dehydrogenase 0.3
cholinesterase 0.2
CPT 0.2
furin 0.2
sulfatase 0.2
isocitrate dehydrogenase 0.1
CPT 0.1
MAP 0.0
PCP -0.0
acetylcholinesterase -0.1
more...
Compound
Simetryn 9.1
MB 1 7.9
2-Nitrophenol 7.5
EOS 7.3
Hydroxylysine 7.1
Quinalphos 6.9
Trimethaphan 6.8
dihydrosphingosine-1-phosphate 6.6
2-hydroxy-3-methoxybenzaldehyde 6.6
T11 6.6
Coronal 6.4
T10 6.3
AICA-riboside 6.3
Ziram 6.1
SD 25 6.1
Methomyl 5.6
Cloxacillin 5.2
Semicarbazide 5.2
Etoricoxib 5.2
Edrophonium 5.0
Cobalamin 4.8
TDT 4.5
Remifentanil 4.4
DPS 4.4
3,4-DAP 4.3
Atracurium 4.3
Emery 4.3
MEP 4.2
TES 4.2
CDH 4.1
TGR 4.1
Chlordecone 4.1
MEP 4.1
DTP 4.0
TIF 4.0
ASK 3.9
keratan sulfate 3.9
Desferal 3.9
Ethylene oxide 3.9
AME 3.8
Botulinum toxin type A 3.8
hexuronic acid 3.8
Ephedrine 3.8
hexuronic acid 3.8
hexuronic acid 3.8
hexuronic acid 3.7
BMD 3.7
Cyanogen bromide 3.7
DMD 3.7
T13 3.7
Droperidol 3.6
Enflurane 3.6
Succinylcholine 3.6
Premarin 3.6
Dextromethorphan 3.6
Halothane 3.5
Etretinate 3.5
6-aminonicotinamide 3.4
Nitroprusside 3.4
DBM 3.3
Aztreonam 3.3
DLT 3.3
DBM 3.3
Hydroxyproline 3.3
Desmopressin 3.3
Prone 3.3
TBC 3.2
Nonylphenol 3.2
PPF 3.2
Dantrolene 3.2
FB2 3.2
Alizarin Red S 3.2
TGT 3.1
BAP 3.1
titanium 3.1
EMC 3.1
Elastin 3.0
Eicosapentaenoic acid 3.0
Melatonin 3.0
BIC 3.0
more...