Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0700208 (scoliosis)
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Human Gene/Protein
Galactose-3-O-sulfotransferase 4 11.9
TMEM184C 11.9
26S protease regulatory subunit 8 11.9
MYH7 protein 11.9
Hypothetical short protein 11.9
G protein-coupled receptor 126 11.6
ladybird homeobox 1 11.3
Ras and Rab interactor 2 11.3
p59 subunit 10.9
golgin, RAB6-interacting 10.9
ZNF541 10.9
SH3TC2 protein 10.9
fibrillin 15 10.9
olfactomedin-like 1 10.9
CMT4C 10.4
RIN2 10.4
LBX1 10.3
SH3TC2 10.2
ROBO3 10.1
PIGK 9.9
TMEM51 9.9
AHNAK nucleoprotein 9.9
TBX6 9.8
chromodomain helicase DNA binding protein 2 9.5
kyphoscoliosis peptidase 9.5
Golgi UDP-GlcNAc transporter 9.5
DSTYK 9.5
GZF1 9.5
CLCF1 9.4
MESP2 9.3
Golgi SNAP 9.3
EXOC6B 9.3
potassium inwardly-rectifying channel 9.3
horizontal gaze palsy with progressive scoliosis 9.3
regulating synaptic membrane exocytosis 2 9.3
MEIS3 9.3
GPR126 9.2
COL27A1 9.2
PPP1R9B 9.2
KLHL7 9.2
RIPPLY2 9.1
TUBGCP4 9.1
SEPN1 9.0
FGD4 8.9
SEDC 8.9
SLC8A2 8.9
NXF5 8.9
GOSR2 8.9
PIGU 8.9
MSTO1 8.7
SNRPB 8.7
Chondroadherin 8.7
DA2B 8.7
ECEL1 8.7
TMBIM4 8.7
HYDIN2 8.7
myosin light chain, phosphorylatable, fast skeletal muscle 8.7
IRX4 8.6
LFNG 8.5
COL23A1 8.5
SEDT 8.5
KIAA1217 8.5
STAC3 8.5
BNC2 8.4
MHC class 1 antigen 8.4
DHX34 8.4
G protein-regulated inducer of neurite outgrowth 1 8.4
MATN1 8.4
Spinocerebellar ataxia 7 8.4
TELO2 8.3
GNB4 8.3
PTDSS1 8.3
calmodulin-binding transcription activator 1 8.3
AIS 8.2
IRX2 8.2
BRWD3 8.2
ZC4H2 8.2
IER3IP1 8.2
RIMS2 8.2
filamin B 8.1
Homeobox protein 8.1
CFTD 8.1
SOC3 8.0
PHOSPHO1 8.0
AICARFT 8.0
FKBP10 8.0
PIGS 8.0
SH3PXD2B 8.0
B3GAT3 8.0
melatonin receptor 1B 7.9
CHRNG 7.9
MEOX1 7.9
KIF22 7.9
FLNB 7.8
NPAS1 7.8
GRIN2C 7.8
AKAP220 7.8
POLE2 7.8
lysyl hydroxylase 1 7.8
PLOD2 7.8
SRS 7.7
fibrillin-2 7.7
transforming growth factor beta receptor II 7.7
IRX1 7.7
EDS VI 7.6
GPAA1 7.6
neuronal growth regulator 1 7.6
COG7 7.6
ADAMTS-2 7.6
phosphatidylinositol-binding clathrin assembly protein 7.6
TNNT3 7.6
LLGL1 7.5
CHRNA 7.5
TMCO1 7.5
B3GALT6 7.5
NFIX 7.5
cardiotrophin-like cytokine 7.5
CISS 7.5
Filamin B 7.5
ubiquitin-protein ligase E3A 7.5
ARHGAP10 7.5
Hes7 7.5
TAL-H 7.5
Ymer 7.5
NXF2 7.5
PIGT 7.5
SLC35A3 7.4
B4GALT7 7.3
MAGEL2 7.3
ZFYVE26 7.3
RGMA 7.3
IFITM5 7.3
exostosin 7.3
COG6 7.3
KIF6 7.3
EOS 7.3
CMT4A 7.2
glucose-6-phosphate 1-dehydrogenase 7.2
CAMK2B 7.2
FBLN1 7.2
DMRT2 7.2
GORAB 7.2
SEC24D 7.2
T12 7.2
Delta3 7.2
gigaxonin 7.2
AAC1 7.2
ZIC4 7.2
Sotos syndrome 7.1
PAX1 7.1
bromodomain containing 4 7.1
CHST14 7.1
DNA helicase B 7.1
CANT1 7.1
CELSR3 7.1
CHM1 7.1
NSD1 7.0
DTDST 7.0
choline kinase beta 7.0
XYLT2 7.0
more...
Disease
Biconcave vertebrae 11.9
Scoliosis associated with other conditions 11.9
Postoperative pneumothorax 11.9
Drug-induced diabetes mellitus 11.9
Horizontal gaze palsy 11.9
Infantile idiopathic scoliosis 11.9
Resolving infantile idiopathic scoliosis 11.9
scoliosis 11.9
MURCS ASSOCIATION 11.9
VACTERL ASSOCIATION 11.9
Neuromuscular scoliosis 11.5
Kyphosis and lordosis 11.4
CISS2 11.1
Iliac vein thrombosis 10.9
CISS1 10.9
BRKS1 10.9
Neuropathic arthritis 10.9
Man-in-the-barrel syndrome 10.9
BRKS2 10.9
Thoracolumbar scoliosis 10.9
partial monosomy 2q 10.9
CMT4C 10.8
Generalized osteopenia 10.3
Miles-Carpenter syndrome 10.3
Amyloid neuropathy 10.3
Progression of rheumatoid arthritis 10.3
Peripheral sensorimotor neuropathy 10.3
Localized tetanus 9.9
SPONASTRIME 9.9
CMT1E 9.9
Sponastrime dysplasia 9.9
Hydrosyringomyelia 9.9
osteoarthritis of the lumbar spine 9.9
Bruck syndrome 9.8
Multiple joint contractures 9.5
Choanal stenosis 9.5
Progressive pulmonary hypertension 9.5
Esophageal atresia/tracheoesophageal fistula 9.5
acrorenal syndrome 9.5
Scheuermann's disease 9.5
Protrusio acetabuli 9.5
arachnodactyly 9.4
recombinant 8 syndrome 9.3
labile personality 9.3
CMT2B1 9.3
Staphylococcus epidermidis meningitis 9.3
Scapuloperoneal spinal muscular atrophy 9.3
diploid/triploid mixoploidy 9.3
Congenital fiber type disproportion 9.2
diastematomyelia 9.1
IS1 9.1
ring chromosome 12 9.1
Distal arthrogryposis 9.1
Wilms' tumor stage 9.1
Linear and whorled nevoid hypermelanosis 9.1
de Barsy syndrome 9.1
Hepatic osteodystrophy 9.1
XLAG 9.1
Neuhauser syndrome 9.0
spondyloperipheral dysplasia 8.9
LQT7 8.9
DA7 8.7
protruded disk 8.7
14q deletion syndrome 8.7
Restrictive lung disease 8.7
CMT2B2 8.7
Marshall-Smith syndrome 8.6
spondylolisthesis 8.6
CACP 8.5
Vertebral column 8.5
trisomy 19q 8.5
Bronchial compression 8.5
Vertebral column 8.5
tetrasomy 15q 8.5
facet joint degeneration 8.5
Spinal instability 8.5
uniparental disomy of chromosome 14 8.4
flatback syndrome 8.4
Jarcho-Levin syndrome 8.4
Proteus syndrome 8.3
Wildervanck syndrome 8.3
partial monosomy 6q 8.3
Rebound hypertension 8.3
ter Haar syndrome 8.3
Brachyolmia 8.3
Pisa syndrome 8.3
Klippel 8.2
Jaffe-Campanacci syndrome 8.2
floppy baby syndrome 8.2
Vertebral anomalies 8.2
partial trisomy 6q 8.2
Superior mesenteric artery syndrome 8.1
trisomy 15q 8.1
tetrasomy 18p 8.1
Degenerative lumbar spinal stenosis 8.1
spondylolysis 8.0
AIS 8.0
Rud syndrome 8.0
MPS IVB 7.9
camptocormia 7.9
syringomyelia 7.9
CMT2K 7.9
Martsolf syndrome 7.9
Atlantoaxial instability 7.9
Roussy-Levy 7.9
Intervertebral disc calcification 7.9
SMA II 7.8
SRS 7.7
Dysostosis 7.7
heritable connective tissue disorder 7.7
pseudocroup 7.7
Meningocele 7.7
Leg length discrepancy 7.7
spondylopathy 7.7
Spondyloepiphyseal dysplasia tarda 7.6
EDS VI 7.6
Hajdu-Cheney syndrome 7.6
funnel chest 7.6
Osteoblastoma 7.6
FRDA 7.5
spondyloepiphyseal dysplasia 7.5
spinal stenosis 7.5
Cardiorespiratory failure 7.5
OIC 7.5
familial hypophosphatemia 7.5
Central core disease 7.4
lumbar spondylosis 7.4
Speckled lentiginous nevus 7.3
HIES 7.3
spinal degeneration 7.3
Neuroaxonal dystrophy 7.3
Andermann syndrome 7.3
EOS 7.3
EOS 7.3
Mayer-Rokitansky-Kuster-Hauser syndrome 7.2
Skeletal dysplasia 7.2
CMT4A 7.2
MOPD II 7.2
sacralization 7.2
FSS 7.2
trisomy 10q 7.2
dentinogenesis imperfecta 7.2
Lumbar spinal stenosis 7.1
trisomy 8q 7.1
Sotos syndrome 7.1
cafe au lait spots 7.1
Mucolipidosis 7.1
unable to remember 7.1
Amniotic band 7.1
partial trisomy 2p 7.1
degenerative disc disease 7.0
hemolymphangioma 7.0
Brown-Sequard 7.0
Premature adrenarche 7.0
osteodysplastic primordial dwarfism 7.0
megalocornea 7.0
Hurler-Scheie syndrome 7.0
LGMD2D 7.0
triplegia 7.0
Giant axonal neuropathy 7.0
more...
Symptom
musculoskeletal back pain 9.3
Generalized fatigue 9.3
poor balance and coordination 9.3
Antecollis 9.1
chest restriction 8.5
Tandem gait 8.5
Easy bruising 8.4
prominent nose 8.3
hypertrophic breast 8.3
Night pain 8.3
Persistent vomiting 8.2
Neurogenic pain 8.0
Sensory ataxia 7.8
Lasegue's sign 7.8
Ankle stiffness 7.7
Quadriceps weakness 7.5
rib pain 7.4
lumbar instability 7.4
Pyramidal signs 7.3
iridodonesis 7.3
Poor weight gain 7.2
torticollis 7.2
thoracic back pain 7.1
Halo 6.9
Q angle 6.8
finger pain 6.6
delayed language development 6.4
lumbar back pain 6.4
hypotonia 6.4
Radicular pain 6.4
Plantar flexion 6.2
back pain 6.2
leg pain 6.2
Central pain 6.2
Referred pain 6.1
coccygodynia 6.1
monoplegia 6.1
abnormal reflex 6.1
distraction 5.9
Organ failure 5.9
Joint hypermobility 5.9
Spontaneous nystagmus 5.9
nerve root irritation 5.9
abnormal breathing 5.7
paraparesis 5.6
abiotrophy 5.5
Lhermitte's sign 5.5
abnormal gait 5.4
athetosis 5.4
spasticity 5.4
low back pain 5.4
Spastic 5.4
loss of balance 5.4
ataxic gait 5.3
sighing 5.3
growing pains 5.2
Buckling 5.2
hypertonia 5.2
chronic back pain 5.1
cardiovascular impairment 5.1
Platypnea 5.1
weakness 5.0
female puberty 4.9
drooling 4.8
thigh pain 4.8
physical appearance 4.7
sciatica 4.6
ophthalmoplegia 4.5
Severe pain 4.5
Physical findings 4.5
Catch 4.4
scaly skin 4.4
hypalgesia 4.4
hyperesthesia 4.4
Postoperative pain 4.4
pachyonychia 4.3
Regurgitation 4.3
arm weakness 4.3
clonus 4.3
neck pain 4.2
dysarthria 4.1
inanition 4.1
leg edema 4.0
Spots 4.0
ataxia 4.0
disturbed balance 4.0
ACHE 4.0
dystonia 3.9
groin pain 3.9
asthenia 3.8
clumsiness 3.8
cerebellar ataxia 3.7
hip pain 3.6
neck stiffness 3.6
elbow pain 3.6
rales 3.5
Psychiatric symptoms 3.5
numbness 3.5
paresis 3.5
enuresis 3.5
limb pain 3.5
blepharospasm 3.4
cyanosis 3.4
metatarsalgia 3.4
joint stiffness 3.4
prostration 3.3
myoclonus 3.3
pain 3.2
exertional dyspnea 3.1
chronic constipation 3.1
incoordination 3.1
constipation 3.1
bone pain 3.1
clubbing 3.1
anesthesia 3.0
hypercapnia 3.0
Respiratory symptoms 3.0
analgesia 3.0
dysesthesia 3.0
arthralgia 2.9
muscle rigidity 2.8
bloating 2.7
adenitis 2.7
neuralgia 2.7
Gastrointestinal symptoms 2.7
stridor 2.7
muscle stiffness 2.6
paresthesia 2.6
atypical chest pain 2.5
shortness of breath 2.5
discomfort 2.5
thinning 2.5
discomfort 2.5
cachexia 2.4
skin irritation 2.4
spasm 2.3
seizures 2.3
photophobia 2.2
hemiplegia 2.2
myalgia 2.2
dyspnea 2.2
livedo 2.1
shoulder pain 2.0
hepatomegaly 1.9
respiratory distress 1.9
Stiffness 1.9
dry skin 1.9
vertigo 1.9
hemoptysis 1.9
collapse 1.9
cough 1.8
hot flashes 1.8
flank pain 1.8
nasal congestion 1.7
epigastric pain 1.7
hypothermia 1.7
regurgitation 1.7
bradykinesia 1.7
nausea and vomiting 1.6
pallor 1.6
more...
Drug
Deflazacort 8.1
Arfonad 6.9
Arfonad 6.3
Somatropin 6.3
CXM 6.2
Sulla 5.9
Triptorelin 5.6
TMX 5.6
Cobalamin 4.8
Metrizamide 4.7
Conray 4.4
Growth hormone 4.2
Growth hormone 4.2
Thiopentone 4.2
Aprotinin 4.0
CTM 3.9
Desferal 3.9
Zmax 3.8
Desferal 3.8
TES 3.7
Premarin 3.6
CPO 3.6
EDR 3.5
CTM 3.5
Dexon 3.5
Posture 3.5
Teriparatide 3.5
Frontal 3.4
Piracetam 3.4
Zinat 3.3
MTC 2.9
AIC 2.8
Propofol 2.8
Vicryl 2.8
GHRP 2.7
BTC 2.7
Azithromycin 2.6
Vitamin B12 2.6
Glide 2.6
Fentanyl 2.5
Depo-Provera 2.5
CAM 2.3
Gelfoam 2.3
Clonidine 2.2
Ceftazidime 2.2
PTC 2.1
DDAVP 2.0
Isoniazid 1.9
DDAVP 1.9
Check 1.9
Salbutamol 1.8
CTC 1.8
Horizon 1.6
Serum albumin 1.6
Vitamin B 1.6
DPA 1.5
CTC 1.5
NBT 1.5
CTA 1.4
Prednisolone 1.3
Monit 1.3
Bayer 1.2
TAC 1.2
CPR 1.1
Award 1.1
Norplant 1.1
nitroglycerin 1.1
TTC 1.0
CSF 0.9
Spectrum 0.9
Dakar 0.8
Paraffin 0.8
Fragment 0.7
Adriamycin 0.7
Spectrum 0.5
Ringer's solution 0.4
Mutagen 0.3
AZT 0.3
Leaf 0.3
Retinoic acid 0.1
MRC 0.1
PCP 0.0
ascorbate -0.0
EE2 -0.1
NADH -0.2
MAP -0.5
ROC -1.1
Dermatol -1.1
Biopolymers -1.2
ENT -1.2
Asthma -1.2
vitamin E -1.2
Cardiovasc -1.4
CTX -1.5
Nephron -1.7
lysine -2.0
ampicillin -2.2
Nephron -2.3
Dial -3.0
Enzyme
PHOSPHO1 8.0
lysyl hydroxylase 6.2
DSR 6.0
galactosyltransferase I 5.7
coagulation factor VIIa 5.2
hatching enzyme 4.8
CTD kinase 4.7
CAO 4.4
CDH 4.3
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.2
GM3 synthase 4.1
esterase D 3.9
pantothenate kinase 3.9
proline oxidase 3.8
PME 3.3
nucleotide pyrophosphatase 3.3
rhodopsin kinase 3.3
transaldolase 3.2
methylmalonyl-CoA mutase 3.2
chymopapain 3.2
chymopapain 3.1
cyclohydrolase 3.1
CAD 3.1
CAD 3.1
CAD 3.0
BIS 3.0
TGT 2.9
nucleotidase 2.9
MMP-3 2.7
myosin ATPase 2.7
lysyl oxidase 2.6
endothelin-converting enzyme 2.5
DAT 2.3
MCS 2.3
acyl-CoA dehydrogenase 2.2
ubiquitin-protein ligase 2.2
methionine synthase 2.2
PHD 2.1
methionine synthase 2.0
cathepsin K 2.0
Rex 2.0
creatine kinase 2.0
ECH 1.8
proprotein convertase 1.8
fumarase 1.7
acyl-CoA dehydrogenase 1.4
alpha-mannosidase 1.3
triphosphatase 1.3
sialyltransferase 1.3
apyrase 1.3
sialyltransferase 1.3
sialyltransferase 1.3
succinic dehydrogenase 1.1
glycerol-3-phosphate dehydrogenase 1.1
AOR 1.1
glycerol-3-phosphate dehydrogenase 1.0
prolyl hydroxylase 1.0
DCF 0.9
alkaline phosphatase 0.8
methylenetetrahydrofolate reductase 0.8
methylenetetrahydrofolate reductase 0.8
phosphoglycerate kinase 0.8
matrix metalloproteinase 9 0.8
citrate synthase 0.7
thromboplastin 0.5
MDP 0.5
succinate dehydrogenase 0.4
phosphorylase 0.4
pepsin 0.4
carboxylesterase 0.3
isocitrate dehydrogenase 0.3
cholinesterase 0.2
CPT 0.2
furin 0.2
sulfatase 0.2
isocitrate dehydrogenase 0.1
CPT 0.1
MAP 0.0
PCP -0.0
acetylcholinesterase -0.1
ATPase -0.2
cytochrome oxidase -0.2
PAH -0.3
MEK -0.3
CPT -0.3
hyaluronidase -0.3
lipase -0.3
transglutaminase -0.4
beta-galactosidase -0.4
MIP -0.4
kinesin -0.4
ceruloplasmin -0.4
CPR -0.5
APC -0.6
pyruvate dehydrogenase -0.6
focal adhesion kinase -0.6
proteasome -0.6
phosphoinositide 3-kinase -0.7
diaphorase -0.7
ERK -0.7
AST -0.7
ACE -0.7
hyaluronidase -0.7
luciferase -0.8
acid phosphatase -0.8
ribonuclease -0.8
ribonuclease -0.8
thrombin -0.8
PARP -0.9
mitogen-activated protein kinase -0.9
glutathione peroxidase -1.0
caspase-9 -1.0
beta-glucuronidase -1.0
glucose-6-phosphate dehydrogenase -1.1
guanylate cyclase -1.2
complex I -1.3
renin -1.3
gamma-glutamyl transpeptidase -1.3
elastase -1.3
collagenase -1.3
alcohol dehydrogenase -1.3
lactate dehydrogenase -1.4
aspartate aminotransferase -1.5
phosphatidylinositol 3-kinase -1.6
catalase -1.6
phospholipase A2 -1.9
neuraminidase -2.0
RNase -2.1
caspase-3 -2.3
RNase -2.3
phosphodiesterase -2.3
superoxide dismutase -2.4
protein kinase -2.5
glutathione S-transferase -2.6
alanine aminotransferase -2.8
reverse transcriptase -3.1
ACS -3.4
protein kinase C -3.7
Compound
Simetryn 9.1
MB 1 7.9
2-Nitrophenol 7.5
EOS 7.3
Hydroxylysine 7.1
Quinalphos 6.9
Trimethaphan 6.8
dihydrosphingosine-1-phosphate 6.6
2-hydroxy-3-methoxybenzaldehyde 6.6
T11 6.6
Coronal 6.4
T10 6.3
AICA-riboside 6.3
Ziram 6.1
SD 25 6.1
Methomyl 5.6
Cloxacillin 5.2
Semicarbazide 5.2
Etoricoxib 5.2
Edrophonium 5.0
Cobalamin 4.8
TDT 4.5
Remifentanil 4.4
DPS 4.4
Atracurium 4.3
3,4-DAP 4.3
Emery 4.3
MEP 4.2
TES 4.2
CDH 4.1
TGR 4.1
Chlordecone 4.1
MEP 4.1
DTP 4.0
TIF 4.0
ASK 3.9
keratan sulfate 3.9
Desferal 3.9
Ethylene oxide 3.9
AME 3.8
Botulinum toxin type A 3.8
hexuronic acid 3.8
Ephedrine 3.8
hexuronic acid 3.8
hexuronic acid 3.8
hexuronic acid 3.7
BMD 3.7
Cyanogen bromide 3.7
DMD 3.7
T13 3.7
Droperidol 3.6
Enflurane 3.6
Succinylcholine 3.6
Premarin 3.6
Dextromethorphan 3.6
Etretinate 3.5
Halothane 3.5
6-aminonicotinamide 3.4
Nitroprusside 3.4
DBM 3.3
Aztreonam 3.3
DLT 3.3
DBM 3.3
Hydroxyproline 3.3
Desmopressin 3.3
Prone 3.3
TBC 3.2
Nonylphenol 3.2
PPF 3.2
Dantrolene 3.2
FB2 3.2
Alizarin Red S 3.2
TGT 3.1
BAP 3.1
titanium 3.1
EMC 3.1
Elastin 3.0
Eicosapentaenoic acid 3.0
Melatonin 3.0
BIC 3.0
TBS 3.0
Cannabidiol 3.0
Leucovorin 2.9
Endosulfan 2.9
Tanshinone 2.9
MTC 2.8
PID 2.8
Carnosine 2.8
DTT 2.8
PID 2.8
Propofol 2.7
BTC 2.6
Toluidine blue 2.6
Isoform 2.6
Deoxyribonucleic acid 2.6
Nicardipine 2.6
Safranin O 2.6
pentosidine 2.6
MAK 2.6
TCE 2.5
APO 2.5
DTT 2.5
THE 2.5
N2O 2.4
Collagen 2.4
TTA 2.4
GAP 2.4
Cap 2.4
Sevoflurane 2.4
BAF 2.4
DDVP 2.4
DAT 2.3
SET 2.3
Polyamine 2.3
MCA 2.3
MCA 2.3
SSD 2.3
Lea 2.2
25-hydroxycholecalciferol 2.2
Ceftazidime 2.2
IPA 2.2
MAD 2.2
IPA 2.2
IPA 2.1
Chondroitin sulfate 2.1
IPA 2.1
Premarin 2.1
Dexmedetomidine 2.1
TBI 2.1
MMC 2.1
Trichloroethylene 2.0
Vincristine 2.0
Azithromycin 2.0
FDP 1.9
Isoflurane 1.9
6-12 1.9
Valproic acid 1.9
Salbutamol 1.8
Xenon 1.8
Guo 1.8
Creatine 1.8
DPA 1.8
A 3 1.8
DPA 1.8
A 71 1.7
UMP 1.7
Alizarin 1.7
Ketamine 1.7
Bisphenol A 1.6
Bisphenol A 1.6
His 1.6
Oil Red O 1.6
DPA 1.6
Thiamine 1.6
Bisulfite 1.6
DPA 1.6
DPA 1.5
CAM 1.5
DFO 1.5
Bicuculline 1.5
more...