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Query: UMLS:C0700208 (scoliosis)
 8,574 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Multicore disease is a rare congenital myopathy that normally stops or makes slow progress. It starts with delayed motor development and frequent falls. Especially the proximal muscles are involved. Other symptoms include contractures of joints, clubfoot, high arched palate, chest deformities, involvement of eye-muscle, cardiac abnormalities, hyperlordosis and scoliosis that normally does not require surgery. We report a rare case of advanced scoliosis in multicore disease requiring operative treatment in a 15-year-old girl. In this case the scoliosis took a rapidly progredient course in puberty close to the end of skeletal growth. A dorsal spondylodesis with USS instrumentation from T9 to L3 was performed. A significant reduction of the scoliosis was obtained. Scoliosis in multicore disease may take a rapidly progredient course. Frequent checks will lead to the initiation of surgical treatment in time.
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PMID:Rapidly progredient scoliosis associated with multicore disease. 970 67

Pedicle screws are widely used to fix posterior spinal implants. However, in some situations, such as at the ends of long constructs in scoliosis correction, the screws may pull out of the pedicles. This limits the use of pedicle screw fixation where bone quality is poor. The aim of this study was to investigate the effect of using either a low-viscosity bone cement (Palacos LV) or a bone augmentation material (Cortoss) on the pullout strength of typical pedicle screws (5 mm USS Schanz screws). Ten lumbar calf vertebrae were implanted with pedicle screws. One screw was inserted as normal, and the contralateral screw was augmented with Palacos LV or Cortoss. A plate was then cemented to the posterior surface of each pedicle and the screws were pulled out using a tensile testing machine. The pullout strength of the non-augmented screws was 1203+/-260 N, while the pullout strength of the augmented screws was 1970+/-220 N (Palacos LV) and 2021+/-342 N (Cortoss). Both Palacos LV and Cortoss significantly increased the pullout strength (p=0.0213 and p=0.0029, respectively). There was no significant difference between the Palacos LV and Cortoss groups (p=0.79).
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PMID:Bone cement or bone substitute augmentation of pedicle screws improves pullout strength in posterior spinal fixation. 1534 56

Scoliosis is defined as a three-dimensional deformity of the spine. The most pronounced component of scoliosis is in the frontal plane, comprising the lateral bending of the spine. Rotation of vertebra takes place in the transverse plane. In most cases of idiopathic scoliosis a decrease of thoracic kyphosis in the sagittal plane occurs. A more rare event is the appearance of a junctional kyphosis between the primary and secondary curve. The instrumentation introduced by Harrington dealt mainly with balancing the bending forces in the frontal plane (distraction of the concavity of the curve), along with fusion of the instrumented area. The multisegmental CD instrumentation allowed for the diminution of the lateral curve in the frontal plane, while at the same time "forcing" an increase of thoracic kyphosis in single curves, and restoration of physiological sagittal curves (thoracic kyphosis lumbar lordosis) in double curve scoliosis. The CD method achieved this good by a 90 degrees rotation of the rod towards the concavity of the curve, "changing" the lateral curve into kyphotic curve. In the AO USS (Universal Spine System) correction is achieved by pulling the hooks towards the rod. The procedure ends with the linking of two rods with transverse connectors forming this way a stable framework. The degree of correction achieved with this method is based on the biomechanic inter relation between the spine and the instrumentation system (application of distraction forces, compensatory forces and translocation of the instrumented segment). Post-op decompensation of the spine is usually the result of incorrect hook fixation, inadequate application of forces (distraction and compression) and use of a standard hook pattern for thoracic curves (type III) in other types of scoliosis.
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PMID:[Biomechanics of scoliosis]. 1575 26

Ventral derotation spondylodesis, according to Zielke, achieves good results in operative treatment of idiopathic thoracic scolioses. Corrections of scoliotic major and secondary curve as well as derotation of the spine are reliably performed. The high rate of rod fractures with subsequent correction loss as well as a proportionate kyphogenic effect represents a problem. By keeping to the correcting principle, anterior double-rod instrumentation (Halm-Zielke Instrumentation) is to be stable in a similar way as posterior double-rod systems. Thus, it is done to facilitate brace-free postoperative care and to prevent excessive kyphotic pattern of the spine. In this prospective study, we retrospectively collected data. We performed radiological follow-up of two groups of patients with idiopathic thoracic scoliosis (King II, III and IV) undergoing an operation with posterior approach (USS instrumentation, posterior group, n=104) in 1997 and 1998 or being corrected with an anterior fusion (Halm-Zielke instrumentation, anterior group, n=37) between 2000 and 2001. Mean age of all patients for operation was 15+/-4 years. Follow-up was performed after 4+/-2 years on average. Preoperative measurements of the major and secondary curve, the lateral profile, rotation and frontal balance (C7 to S1) did not show any significant differences apart from a more severe scoliotic curve in the lumbar spine for the anterior group with appropriately higher lumbar rotation. During follow-up we noticed similar corrections of the thoracic major and lumbar curve in both groups ranging from 49 to 56%. In case of hypokyphotic (T4-T12<or=20 degrees ) scoliosis a kyphogenic effect on the thoracic spine was achieved with both surgical methods. Hyperkyphotic (T4-T12>or=40 degrees ) scolioses were flattened by posterior spinal fusion; the effect of anterior spinal fusion was not significant. Correction of thoracic and lumbar rotation in the anterior group by 37 or 30% was more significant than in the posterior group by 27 or 20%. There was no impact of anterior technique on the balance of the spine whereas the latter shifted by an average of 7 mm to the left in the posterior group. The number of fused segments was significantly smaller in the anterior group with 7+/-1 vertebral bodies (posterior, 11+/-1 vertebral bodies). Rates of complication were identical with 11 or 12% in both groups during follow-up. Anterior and posterior double-rod instrumentations result in comparable corrections for idiopathic thoracic scoliosis of the major and secondary curve. In case of posterior technique, however, four vertebral bodies less were integrated in spondylodesis on average. Balance of the spine did not change after anterior spondylodesis; however, it declined by using the posterior technique. Augmentation of the anterior threaded rod combined with a solid second rod significantly decreases the rate of implant breakages and reliably reduces consecutive correction losses.
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PMID:Comparison of anterior and posterior double-rod instrumentation for thoracic idiopathic scoliosis: results of 141 patients. 1647 Mar 98

A lot of new implant devices for spine surgery are coming onto the market, in which vertebral screws play a fundamental role. The new screws developed for surgery of spine deformities have to be compared to established systems. A biomechanical in vitro study was designed to assess the bone-screw interface fixation strength of seven different screws used for correction of scoliosis in spine surgery. The objectives of the current study were twofold: (1) to evaluate the initial strength at the bone-screw interface of newly developed vertebral screws (Universal Spine System II) compared to established systems (product comparison) and (2) to evaluate the influence of screw design, screw diameter, screw length and bone mineral density on pullout strength. Fifty-six calf vertebral bodies were instrumented with seven different screws (USS II anterior 8.0 mm, USS II posterior 6.2 mm, KASS 6.25 mm, USS II anterior 6.2 mm, USS II posterior 5.2 mm, USS 6.0 mm, USS 5.0 mm). Bone mineral density (BMD) was determined by quantitative computed tomography (QCT). Failure in axial pullout was tested using a displacement-controlled universal test machine. USS II anterior 8.0 mm showed higher pullout strength than all other screws. The difference constituted a tendency (P = 0.108) when compared to USS II posterior 6.2 mm (+19%) and was significant in comparison to the other screws (+30 to +55%, P < 0.002). USS II posterior 6.2 mm showed significantly higher pullout strength than USS 5.0 mm (+30%, P = 0.014). The other screws did not differ significantly in pullout strength. Pullout strength correlated significantly with BMD (P = 0.0015) and vertebral body width/screw length (P < 0.001). The newly developed screws for spine surgery (USS II) show higher pullout strength when compared to established systems. Screw design had no significant influence on pullout force in vertebral body screws, but outer diameter of the screw, screw length and BMD are good predictors of pullout resistance.
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PMID:Pullout strength of anterior spinal instrumentation: a product comparison of seven screws in calf vertebral bodies. 1727 38

Gilbert syndrome (GS) is mainly characterized by intermittent unconjugated hyperbilirubinemia in the absence of hepatocellular disease or hemolysis. Little data are available on operative outcomes in GS patients with spinal deformity surgery.This study has presented a case of GS occurring in the patient with scoliosis.The patient was a 30-year-old female with scoliosis and GS. She was taken a correction form Thoracic 2 to Lumbar 1) levels by using the USS-II spinal system. At 2 years follow-up, the patient was well balanced and pain free. Plain radiographs demonstrated spine solid fusion without correction loss.Although complex scoliosis surgery can be performed safely in these patients with GS, careful perioperative managements including liver function and coagulation function are required.
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PMID:Scoliosis in a Patient With Gilbert Syndrome: A Case Report and Review of the Literature. 2663 44