Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0700208 (scoliosis)
 8,574 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This study investigates mineral metabolism following scoliosis surgery in girls. During the first week there was a significant increase in the secretion of parathormone and a decrease in that of calcitonin. The serum calcium became significantly elevated from between the 3rd and 7th post-operative days. The serum phosphate decreased during the first week and increased significantly thereafter. The urinary excretion of calcium increased five-fold.
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PMID:The effect of scoliosis surgery on parathormone, calcitonin and calcium levels in serum and the urinary excretion of calcium. 727 15

Parathyroid adenoma is the main cause of primary hyperparathyroidism. It is usually asymptomatic and occurs more commonly in adults. It presents with raised parathormone (PTH) and Ca+ levels in serum. Its presentation in adolescence is rare. We report one such incidence of a 14 years old girl who presented with bone pains short stature, and generalized muscle wasting. She was found to have genu valgum at the knee joint, pectus carniatum, scoliosis and cystic changes in pelvis and calvarium. Biochemical investigations and parathyroid Tc-99mMIBI scan confirmed the diagnosis of a parathyroid adenoma. The gland was removed by parathyroidectomy. Till date 12 such cases are reported and none had thoracic, vertebral or calvarium involvement.
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PMID:Presentation of parathyroid adenoma with genu valgum and thoracic deformities. 2671 92