Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0700208 (scoliosis)
8,574 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Lumbar disc herniation in young adolescent is uncommon. Twelve patients of 13 to 16 years old (4 boys and 8 girls) are reported. Traumatic history is encountered only in 1/3 of cases and any spinal abnormality is noted in this series. The rapidity in clinical course is the main difference compared with the lumbosciatalgia of the adult. The mean interval of time between the beginning of clinical signs and surgery is 5 months and a half. A positive straight leg raising test is always present as well as antalgic pseudo-scoliosis. The radiculalgia without lumbalgia is the essential sign in on fourth of cases. The myelography and C.T. scan revealed lumbar disc herniation 5 times in L4-L5 intervertebral space and 7 times in L5-S1 space. The intervertebral disc is reached by unilateral interlaminal approach. The complete removal of the disc is always difficult as the disc is not dehydrated at this age. The radiculalgia disappears immediately in the postoperative period as well as the lumbalgia. The back pain persist some months following the surgery. Up the date any response is noted but the authors think that some prudence is necessary in the evaluation of the results especially because of the incomplete removal of disc in young patients. The authors think also that well hydrated and simply protruded disc of young adolescent may constitute an excellent indication for chemonucleolysis.
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PMID:[Lumbar disk hernia in children. Apropos of 12 cases]. 307 Apr 21

We investigated the incidence, history, clinical findings and results of treatment of lumbar intervertebral disc herniation in adolescents. During the period January 1992 to medio March 1995 we operated on 20 adolescents aged 15 to 19 years (3.4% of all cases of lumbar disc herniation). In the case of five patients there was a delay of more than a year before the correct diagnosis was made. Ten women and ten men were operated on. Median time from start of symptoms to operation was 1 year (1 month-5 years). The dominant symptom was back pain with radiating pain (17/ 20). The straight leg raising test was positive in 19/20. Seven of the patients had scoliosis. The levels of herniation were ten in the 4th lumbar disc and nine in the 5th lumbar disc. The results were excellent or good in all patients, except in one patient in whom no disc herniation had been found. Lumbar disc herniation in adolescents should be considered in the case of back pain and radiating pain to one or both legs. Investigation and treatment should follow the same guidelines as for adults. The short-term results of surgical treatment are good.
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PMID:[Lumbar intervertebral disk prolapse in adolescents]. 897 21