Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0700208 (scoliosis)
 8,574 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 13-month-old female Andalusian was evaluated because of a congenital left deviation of the maxilla and nasal septum, which had resulted in a gross malocclusion of the maxillary incisor teeth. Surgical correction of a deviated nasal septum and premaxilla in a horse was first reported in 1978 and involved a pre-maxilla osteotomy and use of an autogenous rib graft, with a nasal septum osteotomy performed in a second surgery; to the authors' knowledge, no alternative surgical treatments have since been described. In this horse, a new surgical treatment by distraction osteogenesis without nasal septum osteotomy was attempted. After the procedure, the premaxilla and nasal septum deviations were corrected; however, an overjet lesion (rostral projection of maxillary arcade over the mandibular arcade) was evident, for which the owners declined treatment. Compared with previously recommended procedures, distraction osteogenesis appears to be a less invasive treatment for congenital facial deformities and may be considered an option in the treatment of congenital deviation of the nasal septum and premaxilla (wry nose), head scoliosis, brachygnathism, and prognathism in horses.
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PMID:Use of distraction osteogenesis for the correction of deviated nasal septum and premaxilla in a horse. 1507 63

The objective of the current epidemiological study is to show the correlation of various postural abnormalities and spinal deformities and the clinically identifiable dentofacial anomalies by orthodontic examination. Twenty-three children with Scheuermann's disease [mean age: 14 years 8 months; standard deviation (SD): 1 year 8 months] and 28 with scoliosis (mean age: 14 years 7 months; SD: 2 years 3 months) participated in the study. Standardized orthodontic screening protocols were used to map the occlusal relations in the sagittal, vertical, and horizontal dimensions; the space relations of the maxillary and mandibular frontal segment; the temporomandibular joint (TMJ) status; and the facial asymmetries. Statistically significant differences (p<0.05) were found between the values of the examined groups of patients for the following measurements: incisal overjet and overbite, upper and lower midline deviation, mandibular frontal spacing, TMJ pathological symptoms and functional characteristics, and frequency of facial asymmetries. A large percentage of patients with pre-pubertal developments of spinal deformities have various dentofacial anomalies. The majority of these anomalies are present in patients with Scheuermann's disease. Early treatment of the malocclusions closely correlated to postural disorders should minimize the progression of the dentofacial anomalies, making necessary performing orthodontic screening of these patients as early as possible.
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PMID:Orofacial characteristics of adolescents with diagnosed spinal disorders. 2271 94

The purpose of the present study was to assess the prevalence of various types of malocclusions in a group of female patients with adolescent idiopathic scoliosis (AIS), as well as the association between occlusal anomalies and the side, location, and severity of the spine deformity. The study group was comprised of 60 females aged 12-16 years with AIS and 54 healthy controls. Apart from clinical examination, alginate impressions and wax bites were taken. Occlusal traits were assessed on the casts in maximum intercuspation. Data were statistically analyzed with a significance taken as p < 0.05. All patients with AIS showed at least one abnormal orthodontic trait, while 9 (16.7%) patients from the control group had dentition free from any orthodontic anomaly. The difference was statistically significant (p = 0.0032). In the sagittal dimension, patients with AIS had a higher frequency of bilateral distocclusion and unilateral mesiocclusion as compared to the control group (p = 0.0004 and p = 0.0034, respectively). They also showed crowding, increased overjet and overbite more often than healthy age- mates (p = 0.0417, p = 0.0121, and p = 0.0166, respectively). Regarding the association between site, side, or severity of scoliosis and the occurrence of the malocclusion, asymmetric molar occlusion was more frequently observed in patients with right convex (p = 0.0149), while unilateral mesiocclusion, appeared more often in patients with the thoracic apex of the curve (p = 0.0349). The results emphasize a need for collaboration between orthopedists and orthodontists in the complex medical care for scoliotic individuals. Orthodontic treatment can alleviate negative impact that a malocclusion has on the oral health, aesthetics, and psychological well-being of this vulnerable group of patients.
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PMID:Adolescent idiopathic scoliosis and malocclusion - a cross sectional study of female patients without previous orthodontic treatment. 3270 18