Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0699790 (colon cancer)
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Human Gene/Protein
zinc finger protein 292 10.1
PCDHB15 10.1
UBXN2A protein 10.1
RAG cohort 1, importin alpha 1 10.1
RNA binding motif protein 35A 10.1
C6orf102 10.1
CCDC83 10.1
HMGCL protein 10.1
ribonucleotide reductase M2 polypeptide 10.1
Endothelin-converting enzyme-1c 10.1
C6orf64 10.1
Serine/threonine-protein kinase 2 10.1
TMEM208 10.1
ZNF138 10.1
HCA90 10.1
ARHE 10.1
PHLDB3 10.1
SASS6 protein 10.1
NY-CO-45 10.1
AD034 10.1
RBP7 protein 10.1
HRAS-like suppressor 2 10.1
Core 3 synthase 10.1
BCLAF1 protein 10.1
OR51B4 10.1
down-regulated by Ctnnb1, a 10.1
BET1 homolog 10.1
hCLA-iso 10.1
FLJ33803 10.1
CYP2A7 protein 10.1
TMED3 9.8
truncated adenomatous polyposis coli 9.4
UBXN2A 9.3
NY-CO-1 9.1
p21 protein (Cdc42/Rac)-activated kinase 3 9.1
WD repeat domain 8 9.1
DRCTNNB1A 9.1
WNK lysine deficient protein kinase 2 9.1
DBF4B 9.1
PRRG1 9.1
YTH domain containing 2 9.1
TCERG1L 9.1
TBX19 protein 9.1
E3 ubiquitin ligase SMURF1 9.1
Tyrosine-protein kinase receptor 9.1
FMO5 protein 9.1
Protocadherin LKC 9.1
FAM84A protein 9.1
Structural maintenance of chromosomes protein 2 9.1
KRAP 9.1
MICALL1 9.1
ZNF767 9.1
HIST1H2AE 9.1
MAP1D 9.1
HCA59 9.1
ZNF165 protein 9.1
ZNF560 9.1
C17orf82 9.1
Lin-28 homolog B 9.1
angiopoietin-related protein-2 9.1
NY-CO-8 9.1
DNA mismatch repair gene homologue 9.1
RNA polymerase II subunit 11 9.1
CRTC2 protein 9.1
G protein-coupled receptor 137 9.1
betaine-homocysteine methyltransferase 2 9.1
insulin-like growth factor receptor type II 9.1
LMTK2 protein 9.1
cat eye syndrome chromosome region, candidate 2 9.1
HNRNPCL1 9.1
V-set and transmembrane domain containing 2A 9.1
protein phosphatase 1H 9.1
PHF21B 9.1
NWD1 9.1
connector enhancer of kinase suppressor of Ras 1 9.1
TPARM 9.1
JARID2 protein 9.1
TTC22 9.1
TMEM147 9.1
PNMA5 9.1
more...
Disease
Intestinal carcinoma 10.1
Adult dermatomyositis 10.1
colon cancer 10.1
Carcinoma in a polyp 10.1
Adhesion of lung 10.1
Bacterial aneurysm 10.1
Colon cancer 10.0
colon cancer stage 9.5
recurrent colon cancer 9.4
stage III colon cancer 9.2
Acquired megacolon 9.1
dietary carcinogenesis 9.1
enteroptosis 9.1
Rhinocerebral phycomycosis 9.1
Dukes A colon cancer 9.1
Large bowel perforation 9.1
Intestinal ulceration 9.1
endometrial cancer, stage 9.1
Secondary autoimmune haemolytic anaemia 9.1
stage II colon cancer 9.1
metastatic colon cancer 8.8
Duodenocolic fistula 8.8
Aberrant Crypt Foci 8.8
Descending colon 8.5
Small bowel angioedema 8.5
Concato 8.5
Colonic MALToma 8.5
metastatic uterine cancer 8.5
Paraneoplastic dermatomyositis 8.5
Phlegmonous enteritis 8.5
Descending colon 8.5
mucinous adenocarcinoma of the colon 8.2
stage III rectal cancer 8.1
intestinal amyloid 8.1
CONSUMPTION 8.1
Splenic flexure 8.1
Pericholangitis 8.1
Common peroneal nerve palsy 8.1
Paraneoplastic vasculitis 8.1
Sigmoid colon 7.9
Sigmoid colon 7.9
Adenomatous Polyp 7.8
Hemorrhoidal bleeding 7.8
cervical adenosquamous cell carcinoma 7.8
adenocarcinoma of the colon 7.7
Streptococcus bovis infection 7.6
precancerous polyps 7.6
Mucin-producing carcinoma 7.5
Tumor hemorrhage 7.5
sebaceous gland neoplasm 7.5
PCP dependence 7.5
colon growth 7.5
Occupational Cancer 7.4
DHD 7.4
ameboma 7.4
DHD 7.4
Colorectal adenocarcinoma 7.3
adenoma of the colon 7.3
adenomatous polyp 7.3
Mucinous Neoplasm 7.3
Adenomatosis 7.3
Arizona infection 7.3
Raccoonpox 7.3
Perifollicular fibroma 7.3
MHS6 7.3
stage II rectal cancer 7.3
Congenital hypertrophy of the retinal pigment epithelium 7.3
rectal cancer 7.3
colon neoplasm 7.3
Dukes 7.2
Adult celiac disease 7.1
digestive neoplasm 7.1
Colonic obstruction 7.1
rectal cancer stage 7.1
Acrokeratosis paraneoplastica 7.0
Metastatic colorectal cancer 7.0
HNPCC 7.0
Drug-induced neutropenia 6.9
Fibrosing colonopathy 6.9
Periampullary carcinoma 6.9
more...
Symptom
Chills and fever 6.8
feeling worried 6.6
Sister Mary Joseph's nodule 6.5
left lower quadrant pain 5.8
Soft stools 5.5
PUO 5.4
abdominal fullness 5.0
not coping 4.9
left upper quadrant pain 4.7
Functional abdominal pain 4.6
pneumaturia 4.6
Severe diarrhea 4.3
colic 4.3
Skin symptoms 4.0
penile lesion 3.9
corpulence 3.9
anal pain 3.8
frequent urination 3.7
tenesmus 3.5
generalized abdominal pain 3.5
constipation 3.4
nerve pain 3.4
menopausal symptoms 3.3
infant diarrhea 3.3
abdominal discomfort 3.1
bloating 3.0
abdominal pain 3.0
hot flashes 2.9
iliac fossa pain 2.8
No adverse effect 2.8
intestinal bleeding 2.8
precordial pain 2.7
Flare 2.6
nausea and vomiting 2.6
rectal pain 2.5
Scratch 2.5
persistent cough 2.4
Opposition 2.4
Wind 2.3
diarrhea 2.3
dyschezia 2.3
leg edema 2.3
disturbed balance 2.3
nausea 2.2
anorexia 2.1
cachexia 2.1
chronic constipation 2.1
chills 2.0
body pain 2.0
hyperemesis gravidarum 2.0
ataxic gait 2.0
Anoxia 2.0
Gastrointestinal symptoms 1.9
decreased appetite 1.9
fever of unknown origin 1.9
right lower quadrant pain 1.8
right upper quadrant pain 1.7
testicular pain 1.7
flank pain 1.6
vomiting 1.6
hypoproteinemia 1.5
starvation 1.5
asthenia 1.5
epigastric pain 1.5
mastalgia 1.5
irregular bleeding 1.5
consciousness disturbance 1.4
breakthrough pain 1.4
HSA 1.4
overweight 1.4
acute abdomen 1.3
clubbing 1.3
loss of balance 1.3
DNA marker 1.2
dysesthesia 1.2
hoarseness 1.2
acute abdominal pain 1.2
physical appearance 1.1
lightheadedness 1.1
nipple discharge 1.1
more...
Drug
Balsalazide disodium 10.1
Ergamisol 8.8
Edotecarin 8.5
Witch hazel 8.5
Tezacitabine 8.5
1,N6-Ethenoadenine 8.1
OncoScint CR/OV 8.1
Tilomisole 8.1
OncoScint 7.8
CEA-Scan 7.8
Topotecan hydrochloride 7.8
5-Iododeoxyuridine 7.6
Sobuzoxane 7.5
Lexatumumab 7.5
Leucovorin 7.5
Tandutinib 7.3
Doxifluridine 7.1
Uzel 7.0
Caraway 7.0
Canvaxin 6.9
CPT-11 6.9
Oxaliplatin 6.9
Xeloda 6.8
Mapatumumab 6.8
Y-700 6.6
Hemocoagulase 6.6
Isovorin 6.6
Purvalanol 6.6
Loxoribine 6.5
Irinotecan 6.3
Fidarestat 6.3
Fidarestat 6.3
Panitumumab 6.2
Gardenia fruit 5.9
4-Methylimidazole 5.9
Sulofenur 5.8
Edatrexate 5.7
Mevastatin 5.7
Foscavir 5.6
Peridinin 5.6
Vatalanib 5.6
Urso 5.5
Carmofur 5.5
Cetuximab 5.5
Ciglitazone 5.4
8-Azaguanine 5.4
Vioxx 5.3
Tolfenamic acid 5.3
Monastrol 5.2
Irofulven 5.2
Dextran sulfate sodium 5.1
Proleukin 5.0
Levamisol 5.0
GEO 5.0
Pemetrexed disodium 5.0
Polydextrose 4.9
Carbadox 4.9
Methyl aminolevulinate 4.9
Ilomastat 4.9
Romidepsin 4.9
Bevacizumab 4.8
FML 4.8
Alimta 4.8
Effexor 4.8
MT6 4.8
Celebrex 4.7
CDX 4.7
Caramel 4.7
Intron A 4.7
Intron A 4.6
Pemetrexed 4.6
URF 4.6
Temodal 4.6
Pirarubicin 4.6
Panorex 4.6
Darifenacin 4.6
Sunitinib malate 4.5
Epalrestat 4.5
Vitamin K2 4.5
Corn oil 4.4
more...
Enzyme
mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 9.1
zingipain 8.5
beta4GalNAc-T3 8.5
7alpha-dehydroxylase 7.9
kallikrein 13 7.8
APTM 7.8
proprotein convertase 5 7.3
pterin-4alpha-carbinolamine dehydratase 6.5
fragilysin 6.4
N-acetylneuraminylgalactosylglucosylceramide 6.2
matrilysin-2 5.8
linoleic acid isomerase 5.8
uridine hydrolase 5.6
thymidylate synthase 5.6
25-hydroxyvitamin D3 1alpha-hydroxylase 5.5
KLK13 5.4
methioninase 5.3
DNA 3'-phosphatase 5.3
15-hydroxyprostaglandin dehydrogenase 5.3
thymidine phosphorylase 5.2
dihydropyrimidine dehydrogenase 5.2
glycoprotease 5.1
nardilysin 5.1
caspase-7 5.1
dihydropyrimidine dehydrogenase 5.0
2-hydroxyglutarate dehydrogenase 5.0
caspase-7 5.0
uracil phosphoribosyltransferase 5.0
endo-alpha-N-acetylgalactosaminidase 4.9
inositol polyphosphate 4-phosphatase 4.9
cytosine deaminase 4.9
stratum corneum chymotryptic enzyme 4.9
isochorismatase 4.9
folylpolyglutamate synthetase 4.8
caspase-9 4.8
cellobiose 2-epimerase 4.8
kynurenine formamidase 4.7
chondroitin synthase 4.7
STK4 4.7
PARP 4.7
uridine phosphorylase 4.7
hyaluronate lyase 4.6
caspase-8 4.6
protein N-myristoyltransferase 4.6
sucrase-isomaltase 4.6
APC 4.6
3-mercaptopyruvate sulfurtransferase 4.5
spermidine/spermine N1-acetyltransferase 4.5
caspase-6 4.4
sialyltransferase 4.4
sialyltransferase 4.4
sialyltransferase 4.4
caspase-3 4.3
caspase-2 4.3
O-GlcNAc transferase 4.3
caspase-6 4.3
ALDH 4.3
N-acetylglucosaminyltransferase 4.3
caspase-2 4.3
NSY 4.3
GP-I 4.2
azoreductase 4.2
KLK7 4.2
HOA 4.1
orotate phosphoribosyltransferase 4.0
MMP 4.0
ornithine decarboxylase 4.0
GSK 4.0
MHCK 4.0
15-lipoxygenase 4.0
IOR 3.9
BAT 3.9
eEF2 kinase 3.8
histone demethylase 3.8
lactase-phlorizin hydrolase 3.8
HK2 3.8
N-acetylglucosaminyltransferase V 3.8
NADPH:quinone oxidoreductase 3.8
CCS1 3.8
BBE 3.8
more...
Compound
3-phenyl-N-propylacrylamide 10.1
1,3-bis(4-morpholinylmethyl)-2-imidazolidinethione 10.1
ethyl dithiocarbamate 10.1
1-methyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione 10.1
Isogentisin 10.1
N-ethylhydrazinecarbothioamide 10.1
5-indanesulfonamide 10.1
Swertianolin 10.1
C14H21N3O2 9.5
C14H21N3O2 9.5
C14H21N3O2 9.5
C14H21N3O2 9.5
C14H21N3O2 9.5
2-butanone thiosemicarbazone 9.1
C14H21N3O2 9.1
C19H18O11 9.1
5-methyl-1,3-benzodioxole 9.1
Avenanthramide A 9.1
Macbecin II 9.1
Clionasterol 9.1
Dipropyl sulfide 9.1
NeuAcalpha2,6Galbeta1,4GlcNAc 9.1
6-phenyl-1,3,5-triazine-2,4-diamine 9.1
Gardenin B 9.1
N-(1,3-thiazol-2-yl)acetamide 9.1
C14H21N3O2 8.8
C14H21N3O2 8.8
Azoxymethane 8.6
N1,N12-Diacetylspermine 8.5
C14H21N3O2 8.5
ethyl 2-cyano-3-ethoxyacrylate 8.5
N-formylphenylalanine 8.5
allyl butyrate 8.5
Polyporic acid 8.5
Gentisin 8.5
Lupulone 8.3
C8H9NO2 8.3
3,4,5-trimethoxybenzohydrazide 8.1
C14H21N3O2 8.1
2-pyridinecarbothioamide 8.1
5-hydroxy-2-phenyl-4H-chromen-4-one 8.1
2-methyl-1,3-cyclopentanedione 8.1
2,3-diphenylacrylonitrile 8.1
1,2-dimethylhydrazine 7.8
Robinetin 7.8
Tephrosin 7.8
Myrtenal 7.8
Astragaloside III 7.8
Robinin 7.8
11H-indeno[1,2-b]quinoline 7.8
Robinetin 7.8
Myrtenal 7.8
Robinin 7.8
Vernodalin 7.8
Justicidin A 7.8
11H-indeno[1,2-b]quinoline 7.8
Robinetin 7.8
Vernodalin 7.8
benzyl selenocyanate 7.6
Tributyrin 7.6
Loganic acid 7.5
Rubrofusarin 7.5
3-phenyl-1H-indole 7.5
C16H15NO3 7.5
Epoxycholesterol 7.5
9-Anthraldehyde 7.5
7-Hydroxyflavone 7.5
2-Amino-4-nitrophenol 7.5
6H-pyrido[4,3-b]carbazole 7.5
Cyanidin 3-rutinoside 7.5
Leucovorin 7.5
Dinactin 7.3
2-anilinobenzamide 7.3
docosanedioic acid 7.3
6-Hydroxyflavone 7.3
Gracillin 7.3
Virosecurinine 7.3
2,4,6-trihydroxybenzaldehyde 7.3
Baccharin 7.3
Dihydrofisetin 7.3
more...