Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0699790 (colon cancer)
28,837 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 1826
Mol 1719
p53 1510
colon carcinoma 1001
caspase-3 842
catenin 712
Bcl-2 607
p21 551
cage 462
gut 458
beta-catenin 439
DLD 407
cytokine 402
E-cadherin 385
AKT 383
COX-2 380
cyclin D1 376
carcinoembryonic antigen 353
APC 344
cyclooxygenase-2 339
vascular endothelial growth factor 317
NMR 315
KRAS 313
ERK 308
epidermal growth factor receptor 295
PARP 283
PI3K 275
insulin 273
adenomatous polyposis coli 273
She 259
MAPK 258
histone 256
mucin 253
CEA 250
p38 250
mTOR 246
caspase-9 243
tumor necrosis factor 235
cytochrome c 228
TNF 219
BRAF 219
IL-6 218
caspase-8 214
cyclooxygenase 213
ERK1 211
c-Myc 210
CD44 208
proliferating cell nuclear antigen 198
EGFR 195
tyrosine kinase 186
collagen 183
TNM 181
endoplasmic reticulum 180
CD8 178
annexin V 177
ras 174
glycoprotein 172
ATP 171
survivin 171
VEGF 169
MLH1 169
ROS 166
proteasome 161
STAT3 157
matrix metalloproteinase 156
p65 155
c-myc 153
histone deacetylase 152
CRC 151
MEK 150
CD133 150
inducible nitric oxide synthase 148
thymidylate synthase 147
JNK 146
lymphoid 145
p27 142
Fas 138
epidermal growth factor 136
IFN 134
MMP-9 134
more...
Disease
colon cancer 28837
cancer 15677
tumor 9605
colorectal cancer 5506
carcinogenesis 2325
breast cancer 1773
carcinoma 1716
adenocarcinoma 1671
metastases 1619
tumor growth 1517
tumorigenesis 1426
rectal cancer 1160
Colon cancer 1100
lung cancer 979
tumor progression 908
gastric cancer 797
melanoma 785
prostate cancer 613
adenoma 610
colitis 602
liver metastases 556
leukemia 480
inflammatory bowel disease 467
ulcerative colitis 460
pancreatic cancer 447
hepatocellular carcinoma 447
MCF 420
familial adenomatous polyposis 409
ovarian cancer 407
polyposis 379
obesity 353
APC 345
Colon 344
Colon 344
Colon 344
primary tumor 325
Dukes 319
diabetes 294
liver cancer 287
dysplasia 280
liver cancer 241
lymphoma 225
Crohn's disease 215
metastatic colon cancer 209
Lynch syndrome 203
cervical cancer 189
non-small cell lung cancer 180
bladder cancer 179
gastrointestinal cancer 164
squamous cell carcinoma 160
hypertension 156
anemia 152
renal cell carcinoma 148
renal cancer 147
bowel obstruction 146
esophageal cancer 140
glioblastoma 131
lung metastases 129
solid tumor 128
endometrial cancer 126
esophageal cancer 125
adenocarcinoma of the colon 125
multiple myeloma 121
tumor angiogenesis 120
glioma 116
cardiovascular disease 116
lung carcinoma 115
sarcoma 112
Colorectal Cancer 109
retinoblastoma 108
aggressiveness 107
stage III colon cancer 106
carcinomatosis 105
GSH 97
SCID 94
Rectum 93
Rectum 93
Rectum 93
Rectum 93
type 2 diabetes 92
more...
Symptom
diarrhea 262
abdominal pain 223
pain 189
constipation 98
nausea 95
vomiting 85
fatigue 78
starvation 66
anesthesia 62
overweight 61
colic 55
anorexia 55
nausea and vomiting 52
discomfort 29
discomfort 29
dyspnea 28
cough 25
headache 24
cachexia 22
weakness 20
back pain 19
analgesia 18
chills 16
Ill 16
menopausal symptoms 15
chest pain 14
erythema 13
abdominal discomfort 13
collapse 13
abdominal fullness 12
ataxia 12
seizures 12
Wind 12
bloating 12
dizziness 11
angina 11
splenomegaly 11
shortness of breath 9
epigastric pain 9
vertigo 8
exhaustion 8
numbness 8
flushing 8
acidity 8
asthenia 7
HSA 7
hot flashes 7
acute abdomen 7
fever of unknown origin 7
paresthesia 6
pelvic pain 6
dysarthria 6
hepatomegaly 6
hoarseness 6
Sister Mary Joseph's nodule 6
low back pain 6
flank pain 6
arthralgia 5
sleepiness 5
intestinal bleeding 5
cancer pain 5
tenesmus 5
chronic constipation 5
acute abdominal pain 4
decreased appetite 4
lethargy 4
hemoptysis 4
agitation 4
respiratory distress 4
hypoproteinemia 3
tinnitus 3
leg edema 3
pneumaturia 3
acute pain 3
myalgia 3
left lower quadrant pain 3
thinning 3
left upper quadrant pain 3
persistent cough 3
physical appearance 3
more...
Drug
CPT-11 199
ROS 166
lysine 117
Oxaliplatin 96
Leucovorin 84
vitamin E 75
IL-2 70
ascorbate 66
IFN-gamma 65
Irinotecan 60
Bevacizumab 46
GEO 45
Bifidobacterium 44
Cetuximab 38
Adriamycin 38
Dermatol 37
Monit 36
caffeine 31
CSF 29
Taxol 25
lactose 25
Glutathione 25
Cardiovasc 25
ADM 23
MAP 22
ROC 22
Mutagen 21
Indomethacin 20
NADH 19
ABC 19
Gel 18
CAM 18
THF 18
MRC 17
uPA 17
Xeloda 16
ADR 16
Imatinib 16
Gefitinib 15
Vitamin E 15
CTC 15
G-CSF 15
G418 15
ALA 15
niacin 14
Heme 14
EPA 14
Vitamin A 14
CTC 13
CCL 13
Sorafenib 13
Asn 12
Leaf 12
Lovastatin 12
Herceptin 12
Panitumumab 11
Bortezomib 11
Portal 11
Ethanol 10
Nitric Oxide 10
Fluorescein 9
DNase I 9
EE2 9
Pemetrexed 9
Activin 9
Etoposide 9
Norplant 9
Simvastatin 9
Troglitazone 8
Lipiodol 8
Ginger 8
Ginseng 8
CPR 8
ICI 7
Meth 7
citric acid 7
TTC 7
Glycyrrhiza 7
Paraffin 7
Gleevec 7
more...
Enzyme
mitogen-activated protein kinase 813
ERK 753
caspase-3 651
protein kinase 382
luciferase 372
APC 348
PARP 313
focal adhesion kinase 268
MEK 211
caspase-9 190
protein kinase C 190
proteasome 162
thymidylate synthase 156
caspase-8 152
catalase 124
alkaline phosphatase 117
topoisomerase 112
topoisomerase 108
P-glycoprotein 108
superoxide dismutase 104
cdc2 102
GSK 100
ornithine decarboxylase 94
phosphatidylinositol 3-kinase 91
AMP-activated protein kinase 91
reverse transcriptase 90
glutathione S-transferase 88
urokinase-type plasminogen activator 85
peroxidase 74
lactate dehydrogenase 70
ATPase 69
ACS 65
thymidine kinase 63
MMP 63
glutathione peroxidase 60
NQO1 58
phosphoinositide 3-kinase 57
DNA methyltransferase 52
trypsin 51
beta-glucuronidase 49
AMPK 49
collagenase 47
AMPK 42
RNA polymerase 40
dihydropyrimidine dehydrogenase 37
neuraminidase 36
thymidine phosphorylase 35
granzyme B 34
MDR 34
calcineurin 32
phospholipase A2 32
lipoxygenase 31
RNase 31
aldehyde dehydrogenase 30
sialyltransferase 29
RNase 29
sialyltransferase 29
aldehyde dehydrogenase 29
sialyltransferase 29
DNA polymerase 29
aldehyde dehydrogenase 27
aldehyde dehydrogenase 27
aldehyde dehydrogenase 27
caspase-7 27
thrombin 27
beta-galactosidase 27
alanine aminotransferase 27
caspase-7 27
dihydropyrimidine dehydrogenase 27
PDK1 25
NO synthase 25
sucrase 25
IKK 25
glutathione reductase 24
endonuclease 24
phosphodiesterase 24
NADPH oxidase 24
dihydrofolate reductase 24
ribonucleotide reductase 24
phospholipase C 23
more...
Compound
DNA 2941
Dec 2065
Clin 1361
oxygen 728
MTT 695
sodium 614
5-FU 580
water 571
calcium 525
sulfate 404
glucose 392
1,2-dimethylhydrazine 273
tyrosine 255
MDA 244
phosphate 221
TNF 219
vitamin D 214
acetate 206
bromide 198
CPT-11 198
nitric oxide 198
iron 184
TNM 181
serine 178
ethanol 175
galactose 171
ATP 171
methionine 159
cysteine 150
lysine 148
barium 148
hydrogen 145
MEK 145
Curcumin 140
iodine 138
threonine 133
PEG 126
selenium 125
ASA 124
arginine 115
GSH 113
GSH 113
His 111
butyric acid 110
zinc 110
PGE 99
Pac 99
nitrogen 98
methanol 97
PEG 96
folinic acid 96
DSS 93
leucine 90
salt 87
PGE2 86
retinoic acid 83
Adriamycin 82
SN-38 82
Leucovorin 80
copper 78
DPPH 72
ACS 66
ethyl acetate 66
N-acetylcysteine 65
pyrimidine 65
pyrimidine 65
ACS 65
SDS 65
pyridine 64
alanine 63
acridine 63
cAMP 62
urea 61
TOF 61
COX 61
ADR 60
dUTP 60
Resveratrol 57
silver 57
NH2 56
more...