Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0699790 (colon cancer)
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Human Gene/Protein
ribonucleotide reductase M2 polypeptide 10.1
SASS6 protein 10.1
TMEM208 10.1
RNA binding motif protein 35A 10.1
zinc finger protein 292 10.1
UBXN2A protein 10.1
CCDC83 10.1
FLJ33803 10.1
BET1 homolog 10.1
HRAS-like suppressor 2 10.1
CYP2A7 protein 10.1
hCLA-iso 10.1
OR51B4 10.1
down-regulated by Ctnnb1, a 10.1
AD034 10.1
RBP7 protein 10.1
RAG cohort 1, importin alpha 1 10.1
HCA90 10.1
PHLDB3 10.1
Endothelin-converting enzyme-1c 10.1
Core 3 synthase 10.1
C6orf64 10.1
C6orf102 10.1
BCLAF1 protein 10.1
Serine/threonine-protein kinase 2 10.1
PCDHB15 10.1
ARHE 10.1
HMGCL protein 10.1
NY-CO-45 10.1
ZNF138 10.1
TMED3 9.8
truncated adenomatous polyposis coli 9.4
UBXN2A 9.3
HNRNPCL1 9.1
ZNF560 9.1
PNMA5 9.1
FMO5 protein 9.1
p21 protein (Cdc42/Rac)-activated kinase 3 9.1
FAM84A protein 9.1
C17orf82 9.1
more...
Disease
Adhesion of lung 10.1
Bacterial aneurysm 10.1
colon cancer 10.1
Intestinal carcinoma 10.1
Adult dermatomyositis 10.1
Carcinoma in a polyp 10.1
Colon cancer 10.0
colon cancer stage 9.5
recurrent colon cancer 9.4
stage III colon cancer 9.2
Secondary autoimmune haemolytic anaemia 9.1
Acquired megacolon 9.1
dietary carcinogenesis 9.1
Large bowel perforation 9.1
Rhinocerebral phycomycosis 9.1
Intestinal ulceration 9.1
Dukes A colon cancer 9.1
enteroptosis 9.1
endometrial cancer, stage 9.1
stage II colon cancer 9.1
metastatic colon cancer 8.8
Aberrant Crypt Foci 8.8
Duodenocolic fistula 8.8
Concato 8.5
Paraneoplastic dermatomyositis 8.5
Colonic MALToma 8.5
Descending colon 8.5
metastatic uterine cancer 8.5
Descending colon 8.5
Small bowel angioedema 8.5
Phlegmonous enteritis 8.5
mucinous adenocarcinoma of the colon 8.2
Common peroneal nerve palsy 8.1
CONSUMPTION 8.1
intestinal amyloid 8.1
Pericholangitis 8.1
Splenic flexure 8.1
Paraneoplastic vasculitis 8.1
stage III rectal cancer 8.1
Sigmoid colon 7.9
more...
Symptom
Chills and fever 6.8
feeling worried 6.6
Sister Mary Joseph's nodule 6.5
left lower quadrant pain 5.8
Soft stools 5.5
PUO 5.4
abdominal fullness 5.0
not coping 4.9
left upper quadrant pain 4.7
Functional abdominal pain 4.6
pneumaturia 4.6
Severe diarrhea 4.3
colic 4.3
Skin symptoms 4.0
penile lesion 3.9
corpulence 3.9
anal pain 3.8
frequent urination 3.7
tenesmus 3.5
generalized abdominal pain 3.5
constipation 3.4
nerve pain 3.4
menopausal symptoms 3.3
infant diarrhea 3.3
abdominal discomfort 3.1
bloating 3.0
abdominal pain 3.0
hot flashes 2.9
iliac fossa pain 2.8
intestinal bleeding 2.8
No adverse effect 2.8
precordial pain 2.7
Flare 2.6
nausea and vomiting 2.6
rectal pain 2.5
Scratch 2.5
persistent cough 2.4
Opposition 2.4
Wind 2.3
diarrhea 2.3
more...
Drug
Balsalazide disodium 10.1
Ergamisol 8.8
Edotecarin 8.5
Tezacitabine 8.5
Witch hazel 8.5
1,N6-Ethenoadenine 8.1
Tilomisole 8.1
OncoScint CR/OV 8.1
CEA-Scan 7.8
Topotecan hydrochloride 7.8
OncoScint 7.8
5-Iododeoxyuridine 7.6
Sobuzoxane 7.5
Lexatumumab 7.5
Leucovorin 7.5
Tandutinib 7.3
Doxifluridine 7.1
Uzel 7.0
Caraway 7.0
Canvaxin 6.9
CPT-11 6.9
Oxaliplatin 6.9
Xeloda 6.8
Mapatumumab 6.8
Y-700 6.6
Hemocoagulase 6.6
Isovorin 6.6
Purvalanol 6.6
Loxoribine 6.5
Irinotecan 6.3
Fidarestat 6.3
Fidarestat 6.3
Panitumumab 6.2
Gardenia fruit 5.9
4-Methylimidazole 5.9
Sulofenur 5.8
Edatrexate 5.7
Mevastatin 5.7
Peridinin 5.6
Foscavir 5.6
more...
Enzyme
mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 9.1
beta4GalNAc-T3 8.5
zingipain 8.5
7alpha-dehydroxylase 7.9
APTM 7.8
kallikrein 13 7.8
proprotein convertase 5 7.3
pterin-4alpha-carbinolamine dehydratase 6.5
fragilysin 6.4
N-acetylneuraminylgalactosylglucosylceramide 6.2
matrilysin-2 5.8
linoleic acid isomerase 5.8
uridine hydrolase 5.6
thymidylate synthase 5.6
25-hydroxyvitamin D3 1alpha-hydroxylase 5.5
KLK13 5.4
methioninase 5.3
DNA 3'-phosphatase 5.3
15-hydroxyprostaglandin dehydrogenase 5.3
thymidine phosphorylase 5.2
dihydropyrimidine dehydrogenase 5.2
glycoprotease 5.1
nardilysin 5.1
caspase-7 5.1
dihydropyrimidine dehydrogenase 5.0
2-hydroxyglutarate dehydrogenase 5.0
caspase-7 5.0
uracil phosphoribosyltransferase 5.0
inositol polyphosphate 4-phosphatase 4.9
endo-alpha-N-acetylgalactosaminidase 4.9
cytosine deaminase 4.9
isochorismatase 4.9
stratum corneum chymotryptic enzyme 4.9
folylpolyglutamate synthetase 4.8
caspase-9 4.8
cellobiose 2-epimerase 4.8
kynurenine formamidase 4.7
STK4 4.7
chondroitin synthase 4.7
PARP 4.7
more...
Compound
1-methyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione 10.1
ethyl dithiocarbamate 10.1
1,3-bis(4-morpholinylmethyl)-2-imidazolidinethione 10.1
3-phenyl-N-propylacrylamide 10.1
Isogentisin 10.1
N-ethylhydrazinecarbothioamide 10.1
5-indanesulfonamide 10.1
Swertianolin 10.1
C14H21N3O2 9.5
C14H21N3O2 9.5
C14H21N3O2 9.5
C14H21N3O2 9.5
C14H21N3O2 9.5
Dipropyl sulfide 9.1
C14H21N3O2 9.1
Clionasterol 9.1
Macbecin II 9.1
6-phenyl-1,3,5-triazine-2,4-diamine 9.1
Gardenin B 9.1
NeuAcalpha2,6Galbeta1,4GlcNAc 9.1
2-butanone thiosemicarbazone 9.1
C19H18O11 9.1
Avenanthramide A 9.1
N-(1,3-thiazol-2-yl)acetamide 9.1
5-methyl-1,3-benzodioxole 9.1
C14H21N3O2 8.8
C14H21N3O2 8.8
Azoxymethane 8.6
allyl butyrate 8.5
N1,N12-Diacetylspermine 8.5
Polyporic acid 8.5
N-formylphenylalanine 8.5
C14H21N3O2 8.5
Gentisin 8.5
ethyl 2-cyano-3-ethoxyacrylate 8.5
C8H9NO2 8.3
Lupulone 8.3
2-methyl-1,3-cyclopentanedione 8.1
3,4,5-trimethoxybenzohydrazide 8.1
2-pyridinecarbothioamide 8.1
more...