Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0699790 (colon cancer)
28,837 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 1826
Mol 1719
p53 1510
colon carcinoma 1001
caspase-3 842
catenin 712
Bcl-2 607
p21 551
cage 462
gut 458
beta-catenin 439
DLD 407
cytokine 402
E-cadherin 385
AKT 383
COX-2 380
cyclin D1 376
carcinoembryonic antigen 353
APC 344
cyclooxygenase-2 339
vascular endothelial growth factor 317
NMR 315
KRAS 313
ERK 308
epidermal growth factor receptor 295
PARP 283
PI3K 275
adenomatous polyposis coli 273
insulin 273
She 259
MAPK 258
histone 256
mucin 253
CEA 250
p38 250
mTOR 246
caspase-9 243
tumor necrosis factor 235
cytochrome c 228
BRAF 219
more...
Disease
colon cancer 28837
cancer 15677
tumor 9605
colorectal cancer 5506
carcinogenesis 2325
breast cancer 1773
carcinoma 1716
adenocarcinoma 1671
metastases 1619
tumor growth 1517
tumorigenesis 1426
rectal cancer 1160
Colon cancer 1100
lung cancer 979
tumor progression 908
gastric cancer 797
melanoma 785
prostate cancer 613
adenoma 610
colitis 602
liver metastases 556
leukemia 480
inflammatory bowel disease 467
ulcerative colitis 460
pancreatic cancer 447
hepatocellular carcinoma 447
MCF 420
familial adenomatous polyposis 409
ovarian cancer 407
polyposis 379
obesity 353
APC 345
Colon 344
Colon 344
Colon 344
primary tumor 325
Dukes 319
diabetes 294
liver cancer 287
dysplasia 280
more...
Symptom
diarrhea 262
abdominal pain 223
pain 189
constipation 98
nausea 95
vomiting 85
fatigue 78
starvation 66
anesthesia 62
overweight 61
colic 55
anorexia 55
nausea and vomiting 52
discomfort 29
discomfort 29
dyspnea 28
cough 25
headache 24
cachexia 22
weakness 20
back pain 19
analgesia 18
Ill 16
chills 16
menopausal symptoms 15
chest pain 14
erythema 13
abdominal discomfort 13
collapse 13
bloating 12
abdominal fullness 12
ataxia 12
seizures 12
Wind 12
dizziness 11
splenomegaly 11
angina 11
epigastric pain 9
shortness of breath 9
flushing 8
more...
Drug
CPT-11 199
ROS 166
lysine 117
Oxaliplatin 96
Leucovorin 84
vitamin E 75
IL-2 70
ascorbate 66
IFN-gamma 65
Irinotecan 60
Bevacizumab 46
GEO 45
Bifidobacterium 44
Cetuximab 38
Adriamycin 38
Dermatol 37
Monit 36
caffeine 31
CSF 29
Cardiovasc 25
lactose 25
Taxol 25
Glutathione 25
ADM 23
MAP 22
ROC 22
Mutagen 21
Indomethacin 20
ABC 19
NADH 19
CAM 18
THF 18
Gel 18
MRC 17
uPA 17
Xeloda 16
Imatinib 16
ADR 16
G-CSF 15
G418 15
more...
Enzyme
mitogen-activated protein kinase 813
ERK 753
caspase-3 651
protein kinase 382
luciferase 372
APC 348
PARP 313
focal adhesion kinase 268
MEK 211
protein kinase C 190
caspase-9 190
proteasome 162
thymidylate synthase 156
caspase-8 152
catalase 124
alkaline phosphatase 117
topoisomerase 112
topoisomerase 108
P-glycoprotein 108
superoxide dismutase 104
cdc2 102
GSK 100
ornithine decarboxylase 94
phosphatidylinositol 3-kinase 91
AMP-activated protein kinase 91
reverse transcriptase 90
glutathione S-transferase 88
urokinase-type plasminogen activator 85
peroxidase 74
lactate dehydrogenase 70
ATPase 69
ACS 65
thymidine kinase 63
MMP 63
glutathione peroxidase 60
NQO1 58
phosphoinositide 3-kinase 57
DNA methyltransferase 52
trypsin 51
AMPK 49
more...
Compound
DNA 2941
Dec 2065
Clin 1361
oxygen 728
MTT 695
sodium 614
5-FU 580
water 571
calcium 525
sulfate 404
glucose 392
1,2-dimethylhydrazine 273
tyrosine 255
MDA 244
phosphate 221
TNF 219
vitamin D 214
acetate 206
bromide 198
CPT-11 198
nitric oxide 198
iron 184
TNM 181
serine 178
ethanol 175
galactose 171
ATP 171
methionine 159
cysteine 150
lysine 148
barium 148
hydrogen 145
MEK 145
Curcumin 140
iodine 138
threonine 133
PEG 126
selenium 125
ASA 124
arginine 115
more...