Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0699790 (colon cancer)
 28,837 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Atraumatic infections due to Clostridium septicum are known to be associated with immunosuppression or even malignancy. In this case report, we present a patient with severe Clostridium septicum infection related to advanced colon cancer that had not previously been diagnosed. The case demonstrates the strong association between Clostridium septicum infections and malignancy, particularly in the presence of other predisposing diseases such as diabetes mellitus. It strongly suggests excluding malignant neoplasms, especially of the gastrointestinal tract, when severe Clostridium septicum infections occur. Moreover, if patients with known colorectal or other malignancy develop septicaemia or spontaneous gas gangrene, clinicians should be aware of Clostridium septicum as one of the main causative agents, as early diagnosis and aggressive treatment are important to improve prognosis.
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PMID:[Spontaneous gas gangrene in a diabetic patient with Clostridium septicum]. 1602 94

Clostridium septicum infection is a rare cause of spontaneous nontraumatic gas gangrene. The resultant myonecrosis is acutely painful and rapidly fatal. The infection occurs in the absence of trauma and is usually associated with an underlying malignancy. A case of spontaneous gas gangrene of the upper limb caused by C. septicum infection associated by carcinoma of the colon is presented, with a review of the literature.
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PMID:Spontaneous gas gangrene associated with occult carcinoma of the colon: a case report and review of literature. 1654 24