Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0699790 (colon cancer)
 28,837 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An analysis of the local and systemic perioperative complications is conducted to explore the risk of resection of colon cancer. In a retrospective study we analyzed 231 consecutive patients operated on between 1984 and 1988. The mean age was 70 (37-91) years. The operations consisted in 3 ileocecal resections, 144 right hemicolectomies, 10 resections of the transverse colon, 22 left hemicolectomies, 77 resections of the sigmoid colon and 5 subtotal colonic resections. 2 patients (0.9%) had a clinical leakage of the anastomosis. 3 patients were reoperated: one because of anastomotic leakage and two because of ileus due to small bowel adhesions. 2 patients with uncomplicated local healing died within 30 days after the operation from systemic complications (mortality 0.9%). It is concluded that with standardized preoperative bowel preparation, prophylactic perioperative antibiotics and modern anesthesia, the resection of colon cancer is today possible with minimal perioperative risk.
 ...
PMID:[Perioperative morbidity and mortality of colon resection in colonic carcinoma]. 162 49

The authors analyse 62 patients suffering from carcinoma of the colon with metastases in the lungs. Six patients were operated on not only for primary tumor of the colon but also in solitary metastatic affection of the lungs. The interval during which a solitary metastasis in the lung was detected lasted 18.1 months on average. Palliative resection of the colon when distal metastases were found in the lungs was conducted in 21 patients; in 7 of these patients, metastases in the lungs were recognized before the operation while in 2 the diagnosed solitary metastasis was mistaken for carcinoma of the lung and only during operation for ileus was the tumor of the colon discovered. The postoperative mortality was 23.8%, in 17.7%, death was caused by incompetence of anastomosis sutures.
 ...
PMID:[Treatment of colonic cancer with metastases to the lungs]. 169 93

The analysis of treatment and diagnosis is presented for 168 colon cancer patients with occlusive ileus. Late diagnosis is responsible for high percentage of palliative operations (61.9%) with a 26% mortality. Radical surgery involves, as a rule, delayed primary one-stage resection and establishment of a single- or doubled-barreled anus. The mortality in this case reaches 19%. Advances in colon cancer treatment results and ways to reduce mortality in this conditions lie in early diagnosis and better knowledge by general practitioners of occlusive ileus pathogenesis and clinical appearance.
 ...
PMID:[Obturation ileus in cancer of the large intestine]. 170 45

Six cases of lung cancer combined with the disease which has needed semi-emergency operation, two cases of unstable angina, two of ileus due to colon cancer, one of impending rupture of abdominal aortic aneurysm and one of purulent cholecystitis with cholelithiasis, were discussed. Mean age was 62.0 years (range, 36 to 73); four were male and two were female. Case 1 and 2 were admitted with anterior chest pain, Case 3 with lumbago and abdominal pain, Case 4 and 5 with an abnormal shadow on chest x-ray film and Case 6 with abdominal pain. Of the two with unstable angina, one was operated on with right upper lobectomy during the first months after aorto-coronary bypass. Of the two with colon cancer, one was operated on with right upper lobectomy during about 5 weeks after right hemi-colectomy. Case 3 with abdominal aortic aneurysm operated on with left upper lobectomy during 4 weeks after replacement of abdominal aorta. Case 4 with cholecystitis was operated on with left pneumonectomy during about 3 weeks after cholecystectomy. The postoperative course of 4 cases and the post-chemotherapy condition of 2 cases were uneventful.
 ...
PMID:[Evaluation of treatment of lung cancer combined with the disease which has needed a semi-emergency operation]. 188 16

Reported is the case of a 66-year-old woman who complained of a pain in the upper abdomen. A barium enema revealed a stenosis in the transverse and sigmoid colon and since her ileus worsened, an emergency operation was performed, which revealed an unresectable transverse colon cancer with a diffuse peritoneal metastases. After closing the wound, the patient was treated with local thermotherapy of the abdomen using an RF wave in combination with chemotherapy and immunotherapy. Later, since the tumor could not be palpated and the tumor markers dissipated, a reoperation was performed, and it was found that diffuse metastases had completely disappeared from the peritoneum. Further, a histopathological study did not disclose any tumor cells. Therefore, as the cancer was remarkably reduced, a partial transverse and descending colon colectomy was performed.
 ...
PMID:[An unresectable colon cancer with a diffuse metastases that turned resectable following thermotherapy with chemoimmunotherapy]. 212 46

A 51-year-old man with congenital diaphragmatic hernia and enterothorax was found to have persisting leucocytosis (25,000/microliters), diarrhoea and weight loss (20 kg). Computed tomography (CT) revealed intrahepatic space-occupying lesions. CT-directed needle biopsy demonstrated adenocarcinoma metastases. Colon contrast enema was ambiguous. Since no primary tumour had been found, ambulatory treatment with 5-fluorouracil was started. After initial improvement diarrhoea and obstipation alternated so that the patient finally gave permission for coloscopy to which he had not consented at first. It revealed a carcinoma of the colon located in the thorax about 10 cm oral to the left colonic flexure. Progressive ileus necessitated an ileodescendostomy for palliation. The patient died three months later while on symptomatic treatment.
 ...
PMID:[Colonic carcinoma localized in the chest in enterothorax due to congenital diaphragmatic hernia]. 220 44

We report the case of a 55-year-old woman with intermittent fever of unknown origin of several weeks duration. The past medical history was uneventful, as was the review of systems. After an extensive work-up, which did not produce the cause of the fever, the patient developed abdominal pains with signs of sub-ileus. In further examinations, a large stenotic carcinoma of the colon was found.
 ...
PMID:[Febrile status]. 281 8

Direct outcomes of 215 urgent operations for complicated forms of carcinoma of the colon were analyzed. Operations for acute ileus were performed in 147 patients, for perforation of the bowel and peritonitis in 45 patients, for profuse intestinal bleedings in 23 patients. The lethality after the urgent operations was 32.5%. Operations with the removal of the primary tumor give better direct and remote results.
 ...
PMID:[Emergency operations in complicated forms of cancer of the colon]. 378 75

Over the period 1963 to July 30, 1978 a total of 312 patients with clinical picture of acute or subacute mechanical ileus were admitted to the surgical department of the district hospital in Targovishte, and 227 of them were operated on as emergency cases. During the first period covering 1963-1970, the number of operated patients amounted to 78 of which eighteen - a 23.07 per cent lethality. During the second out of 149 patients operated on twenty-three died which makes a 15.63 per cent lethality. A detailed analysis is made of the factors influencing the treatment results, and the conclusion is reached that the age of patients, cause of obstruction and level of ileus have an essential practical bearing. It is assumed that in small intestinal ileus the 11.95 per cent lethality recorded among the 92 operated patients, against 26.3 per cent in the first period, is due first and foremost to the radical operative interventions applied, aimed not only to tackle the ileus problem but also to remove the prime cause of ileus, as well as to the measures undertaken - mesenteriplication after Childs-Philips and its modification - to prevent early and late recurrence of the ileus. The tactics adopted in the various forms of small intestinal ileus are analyzed in detail. The operative methods used and lethality recorded in colonic ileus are also analyzed. Here the condition presents volvulus of the sigma and carcinoma of the colon. The immediate results of the applied radical and palliative operations are evaluated. Radical surgery of the right half of the colon is more justified. Ileus of the left half of the colon demands meticulous assessment of the local status prior to take the decision about undertaking radical intervention on passage indications. The indications for resection of the colon and its completion with anastomosis or provisory preternatural anus are discussed. The lethality rate recorded in 57 patients operated for colonic ileus during the second period amounts to 21 per cent.
 ...
PMID:[Results and conclusions based on our experience with the surgical treatment of mechanical intestinal obstruction]. 744 69

Since April 1990, multiple metastatic liver tumors have been treated with intraoperative ultrasound-guided microwave tumor coagulation (MTC) in combination with postoperative intraarterial chemotherapy. Twenty-four patients have been enrolled in this therapeutic modality and two of five patients treated in 1990 achieved long-term survival. In case 1, a 67-year-old woman was diagnosed as bearing gastric leiomyosarcoma with multiple liver metastasis. Total gastrectomy was performed, and six hepatic lesions were treated by MTC along with implantation of an intraarterial reservoir. Postoperative intraarterial chemotherapy was administered in a selective or subselective manner. Her survival time was 4 years and 6 months. In case 2, a 47-year-old man was diagnosed as having liver metastasis from descending colon cancer 1 year and 5 months after left hemicolectomy. When he was laparotomized for the treatment of adhesive ileus, three metastatic liver tumors were treated with MTC. Afterward, he underwent hepatic resection, intraarterial and intraportal chemotherapy. He survived for 5 years and 5 months after being diagnosed with liver metastasis. MTC is one of the useful modalities for the treatment of multiple liver metastasis.
 ...
PMID:[Long-term survival in two cases of multiple liver metastasis successfully treated with intraoperative ultrasound-guided microwave tumor coagulation (MTC)]. 757 91


1 2 3 4 5 6 7 8 9 Next >>