Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0699790 (colon cancer)
 28,837 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two cases of ulcerative colitis in the Bantu are reported. One patient presented with fulminant acute colitis with toxic dilatation of the colon and massive rectal haemorrhage, the second with chronic, continuous diarrhoea for over twenty years, culminating ultimately with carcinoma of the colon. The aetiology of ulcerative colitis is discussed, together with the problems of specific diagnosis encountered in a population with a high incidence of parasitic infestation and infective diarrhoea. It is considered that the sparseness of reports and apparent rarity of this disease in the Bantu may reflect a failure of detection rather than a true infrequent occurrence. The natural incidence of the disease may be on the increase.
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PMID:Ulcerative colitis in the South African Bantu. 531 8

Prevalence of infestation with Schistosoma japonicum was highly correlated with mortality from colorectal cancer in 89 communes in four counties of Jiangsu province, China (rank correlation coefficient = 0.68) in 1973-75, and with incidence of colorectal cancer in 24 communes of Haining county, Zhejiang province in 1977-79. No similar correlations were seen with lung cancer. The presence or absence of a past history of schistosomiasis was ascertained from 154 patients with cancer of the rectum, 98 patients with cancer of the colon and two sets of individually matched control patients. One set consisted of patients with non-gastrointestinal cancer and the other of near neighbours of the colorectal cancer patients. In patients with a history of schistosomiasis, relative risk of rectal cancer was 8.3 (95% confidence interval 3.1 to 22.6) when other cancer patients were used as controls and 4.5 (95% confidence interval 1.7 to 12.1) with neighbourhood controls. Relative risk of colon cancer was not significantly increased (1.20 with 95% confidence interval 0.48 to 3.18 in a matched triplet analysis) in association with schistosomiasis.
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PMID:Schistosoma japonicum and colorectal cancer: an epidemiological study in the People's Republic of China. 648 Jan 52

A 60-year-old man was admitted due to rectosigmoid colon cancer, and a hepatic mass was incidentally found during the staging work-up. The mass appeared cystic with a thick wall and contained multiple bizarre cord-like structures on ultrasound, computed tomography and magnetic resonance imaging. The differential diagnoses included organizing abscess/hematoma, foreign body granuloma and parasite infestation. Serologic study revealed anti-sparganum antibodies. Over 4-year follow-up, the patient did not complain of symptoms, and no changes in the characteristics of the liver mass were observed. Hepatic sparganosis is rare; only two cases have been clinically reported, and no detailed radiologic description was available until now. This case report presents a detailed radiologic description of a hepatic mass that could most likely represent hepatic sparganosis.
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PMID:Presumptive case of sparganosis manifesting as a hepatic mass: A case report and literature review. 2784 43