Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
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Drug
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Target Concepts:
Gene/Protein
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Query: UMLS:C0699790 (
colon cancer
)
28,837
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Disseminated superficial porokeratosis
(
DSP
) is a specific disorder of keratinization. Genetic studies show that
DSP
is an autosomal dominant trait. Clinically, the lesions show a sharply demarcated and hyperkeratotic plaque with central atrophy. The lesions appear mainly in the extremities and generally develop with bilateral symmetry. Unusual cases of
DSP
accompanied by severe pruritus have been reported as "eruptive pruritic papular porokeratosis" or "inflammatory
DSP
." Histopathologically, inflammatory
DSP
is characterized by the presence of cornoid lamella with a dense infiltration of eosinophils and lymphocytes in the perivascular area of the upper dermis. Here we report a case of inflammatory
DSP
in a 84-year-old man with
colon cancer
who presented with multiple hyperpigmented atrophic macules.
...
PMID:A case of inflammatory disseminated superficial porokeratosis in a colon cancer patient. 2052 74
