Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0699790 (colon cancer)
 28,837 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 69-year-old man underwent right middle lobectomy because of the tumor lesion in the right middle lung. He had ever been in Celebes and China (riverside area of the Yangtze), the infected area of schistosomiasis japonica, for military service during the World War II. Resected lung specimen was carefully examined at the department of pathology in our hospital. Several ova of Schistosoma japonicum were discovered scattered in the specimen, and the pathological feature of the lung lesion was revealed to be metastasis of the sigmoid colon cancer which was resected 4 years ago at a certain hospital. The ova of Schistosoma japonicum were also distributed near the colon lesion. Recently in Japan, it is said, acute infected case of schistosomiasis japonica has been ceased, however, in cases of chronic stage of this disease, hepatoma or lower intestinal cancers are still discovered through the careful follow up study.
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PMID:[A case of metastatic lung tumor of the colon cancer with ova of schistosoma japonicum in the resected lung specimen]. 251 5

Prevalence of infestation with Schistosoma japonicum was highly correlated with mortality from colorectal cancer in 89 communes in four counties of Jiangsu province, China (rank correlation coefficient = 0.68) in 1973-75, and with incidence of colorectal cancer in 24 communes of Haining county, Zhejiang province in 1977-79. No similar correlations were seen with lung cancer. The presence or absence of a past history of schistosomiasis was ascertained from 154 patients with cancer of the rectum, 98 patients with cancer of the colon and two sets of individually matched control patients. One set consisted of patients with non-gastrointestinal cancer and the other of near neighbours of the colorectal cancer patients. In patients with a history of schistosomiasis, relative risk of rectal cancer was 8.3 (95% confidence interval 3.1 to 22.6) when other cancer patients were used as controls and 4.5 (95% confidence interval 1.7 to 12.1) with neighbourhood controls. Relative risk of colon cancer was not significantly increased (1.20 with 95% confidence interval 0.48 to 3.18 in a matched triplet analysis) in association with schistosomiasis.
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PMID:Schistosoma japonicum and colorectal cancer: an epidemiological study in the People's Republic of China. 648 Jan 52

Some reports suggest the positive correlation between Schistosoma japonicum infection and colorectal cancer, however the sufficient evidence that supports a causal relationship between them has not been established. Japan used be an endemic area of S. japonicum infection for 40 years ago. But now all of Japan is a non-endemic area of S. japonicum infection. We report a case of ascending colon cancer associated with deposited ova of S. japonicum in non-endemic area.
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PMID:Ascending colon cancer associated with deposited ova of Schistosoma japonicum in non-endemic area. 2771 58