Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0699790 (colon cancer)
28,837 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Amoeboma is an inflammatory mass of the colon. It is uncommon with most cases occurring in Latin America and South Africa. When amoeboma is the presenting symptom of amoebiasis, it poses the problem of differential diagnosis of colon cancer. This report describes the case of a 60-year-old patient who presented a painful mass in the left hypochondrium. Radiologic and endoscopic examinations depicted a ring-like stenosis of the transverse colon in association with a mesenteric reaction. The presumptive diagnosis was colon cancer and the patient was referred to the National Oncology Institute for surgical treatment. Histological examination of the surgical specimen after segmental colectomy confirmed diagnosis of intestinal amoeboma. The patient was treated medically using metronidazole. Since intestinal amoebiasis is common in our country, amoeboma must be considered as a rare but potential diagnosis in patients presenting masses of the colon. Differential diagnosis of carcinoma is necessary to avoid the risks associated with unnecessary surgery.
...
PMID:[Diagnostic problems associated with intestinal amoeboma: case report]. 1546 Jan 49

Amebic colitis is common in developing countries, with its variable and non-specific symptoms. Amebomas occur rarely, resulting from the formation of annular granulation tissue, usually in the cecum and in the ascending colon. This report describes the case of a 59-year-old male who presented with abdominal pain. Radiological examination depicted concentric thickening of the cecal wall with mass formation and a cystic lesion in the liver. The endoscopy performed showed a growth in the ascending colon. Biopsy revealed extensive necrosis and inflammatory cells. The patient was referred to this hospital for surgical treatment with a provisional diagnosis of carcinoma of the colon. Peroperatively, a cecal mass was identified. However, suspected secondaries were not seen on the surface of the liver. Histological examination of the right hemicolectomy specimen revealed cecal and ascending colon amebomas. Trophozoites of Entamoeba histolytica were better recognized after periodic acid-Schiff staining. Treatment with Metronidazole for 2 weeks followed by diloxanide furoate for an additional 2 weeks was administered. The liver lesion resolved completely after 8 weeks. Colonic ameboma accompanied by amebic liver abscess may be misdiagnosed as metastatic colon cancer. A high index of suspicion is essential for diagnosis when dealing with colonic masses and liver lesions, especially in the tropics.
...
PMID:Ameboma of the colon with amebic liver abscess mimicking metastatic colon cancer. 1933 22

Amoeboma is an inflammatory mass of the colon. It can be an inaugural symptom and thus pose the problem of differential diagnosis with colon cancer. The purpose of this report is to describe the case of a 43-year-old patient who presented with acute abdomen. Physical examination revealed a perforated circumferential mass in the sigmoid colon. Based on a presumptive diagnosis of colonic cancer complicated by perforation, segmental colectomy was performed. Histological examination of the surgical specimen demonstrated colonic amoeboma. The patient was treated using metronidazole. Although rare, amoeboma must be considered in differential diagnosis of cancer of any colonic mass.
...
PMID:[Complicated sigmoid tumor: perforated amebiasis]. 2236 43

Ameboma is a rare complication of amebic colitis presenting as a mass of granulation tissue with peripheral fibrosis and a core of inflammation related to amebic chronic infection. The initial presentations are usually obstruction and low gastrointestinal bleeding. The most common sites are the ascending colon and the cecum. It may mimic colon carcinoma, Crohn's disease, carcinoma of the colon, non-Hodgkin's lymphoma, tuberculosis, fungal infection, AIDS-associated lymphoma and Kaposi's sarcoma in colonoscopy findings. The therapeutic strategy should be combined with antibiotics for invasive dysentery and eradication of luminal cysts.
...
PMID:Ameboma: a colon carcinoma-like lesion in a colonoscopy finding. 2440 82

Colonic ameboma is a rare benign inflammatory tumor due to the infection by Entamoeba histolytica and poses frequently the problem of colon cancer. We report a case of a 52 year-old patient who presented a cecal amoeboma revealed by a painful mass in the right iliac fossa. Radiologic and endoscopic examinations depicted a parietal thickening of the right colon and the cecum. A presumptive diagnosis of colon cancer was firstly discussed. Confirmation of ameboma was made on pathological examination, PCR and serology.
...
PMID:[Ileocecal ameboma: a case diagnosed by pathology and molecular biology]. 2483 62