Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0694563 (eds)
 1,062 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An activation-tagged allele of activated disease resistance 1 (ADR1) has previously been shown to convey broad spectrum disease resistance. ADR1 was found to encode a coiled-coil (CC)-nucleotide-binding site (NBS)-leucine-rich repeat (LRR) protein, which possessed domains of homology with serine/threonine protein kinases. Here, we show that either constitutive or conditional enhanced expression of ADR1 conferred significant drought tolerance. This was not a general feature of defence-related mutants because cir (constitutive induced resistance)1, cir2 and cpr (constitutive expressor of PR genes)1, which constitutively express systemic acquired resistance (SAR), failed to exhibit this phenotype. Cross-tolerance was not a characteristic of adr1 plants, rather they showed increased sensitivity to thermal and salinity stress. Hence, adr1-activated signalling may antagonise some stress responses. Northern analysis of abiotic marker genes revealed that dehydration-responsive element (DRE)B2A but not DREB1A, RD (response to dehydration)29A or RD22 was expressed in adr1 plant lines. Furthermore, DREB2A expression was salicylic acid (SA) dependent but NPR (non-expressor of PR genes)1 independent. In adr1/ADR1 nahG (naphthalene hydroxylase G), adr1/ADR1 eds (enhanced disease susceptibility)1 and adr1/ADR1 abi1 double mutants, drought tolerance was significantly reduced. Microarray analyses of plants containing a conditional adr1 allele demonstrated that a significant number of the upregulated genes had been previously implicated in responses to dehydration. Therefore, biotic and abiotic signalling pathways may share multiple nodes and their outputs may have significant functional overlap.
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PMID:Drought tolerance established by enhanced expression of the CC-NBS-LRR gene, ADR1, requires salicylic acid, EDS1 and ABI1. 1514 82

Salicylic acid plays an important role in the active oxygen metabolism and the photosynthesis of the plant. Wild type Arabidopsis thaliana (ecotype Columbia) and it's two different mutants were used as experimental material: one is the cpr5 mutant which has an abundant endogenesis SA level under stress conditions, and the other is the eds-4 mutant which has a lacking endogenesis SA level under stress conditions. The leaves of those three different Arabidopsis were treated with 100, 300, and 500 micromol x L(-1) concentrations of salicylic acid, respectively. The fluorescence emission spectra and the delayed fluorescence were detected respectively. The authors found that there was a slight elevation in the photosynthetic efficiency of PS II of the WT and eds-4 leaves with 100 and 300 micromol x L(-1) SA treatment. However, there was a decrease in the photosynthetic efficiency and even a stress of the cpr5 leaves with 100 and 300 micromol x L(-1) SA treatment. It was also showed that there came to be an obvious stress of the leaves of all three different kinds of Arabidopsis with 500 micromol x L(-1) SA treatment and the photosynthetic efficiency of them decreases sharply. The generation of active oxygen was also detected with the DCF labeling under 500 micromol x L(-1) SA treatment. The authors found that there was an obvious accumulation of active oxygen along with the time under SA treatment.
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PMID:[Effects of exogenous salicylic acid on photosynthesis in Arabidopsis leaves based on fluorescence spectra and delayed fluorescence technique]. 1983 40