Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0684275 (haemophilia)
 10,958 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
factor VIII 2432
Sep 1151
hemophilia A 882
factor IX 772
FVIII 682
prothrombin 466
von Willebrand factor 450
VIII 429
factor VII 381
thrombin 357
Factor VIII 329
FIX 279
thromboplastin 272
coagulation factor VIII 212
X-linked 173
CD4 159
tissue factor 148
fibrinogen 135
Mol 116
Factor IX 91
albumin 88
interferon 84
factor XI 78
X-linked recessive 70
factor V 69
collagen 63
coagulation factor IX 62
tissue factor pathway inhibitor 56
She 53
vWF 51
glycoprotein 51
MRI 50
clotting factor VIII 49
antithrombin 48
FXI 43
CD8 41
factor Xa 41
arginine vasopressin 41
HLA 40
protein C 40
vasopressin 37
Pol 37
surface antigen 35
cytokine 34
X-chromosome 32
heavy chain 31
CD20 29
antithrombin III 26
IgA 26
IFN 24
alanine aminotransferase 24
Prothrombin 23
serine protease 23
IL-10 22
B19 22
protein S 20
PLA 19
plasminogen 19
factor XII 19
IL-6 18
factor V Leiden 17
tissue plasminogen activator 17
hemoglobin 17
ADP 16
IL-4 16
IL-2 16
p24 15
SDS 15
CD25 15
coagulation factor VII 15
GPIIb 14
thrombomodulin 14
BDE 14
lymphoid 14
EPI 14
serum albumin 13
FPP 13
alkaline phosphatase 13
DIC 13
UTR 13
p24 antigen 13
JAMA 13
interferon-alpha 13
reserved 12
prion 12
kit 12
endonuclease 12
insulin 12
ferritin 12
anonymous 11
interferon alpha 11
fused 11
telomeric 11
TNF 11
dilute 11
IgG3 11
San 10
beta 2-microglobulin 10
severe combined immunodeficiency 10
HLA-DR 10
endoplasmic reticulum 10
major histocompatibility complex 10
PEG 10
Polymerase 10
CCR5 10
thrombin-activatable fibrinolysis inhibitor 10
AST 10
chronic renal failure 10
plasma glycoprotein 9
growth hormone 9
P-selectin 9
Hip 9
interleukin-2 9
Men 9
ENT 9
LDL receptor 9
ARC 9
IgE 9
human leucocyte antigen 8
SPCA 8
erythropoietin 8
NHS 8
lectin 8
IL10 8
CGA 8
glycoprotein IIb 8
gut 8
urokinase-type plasminogen activator 8
Y chromosome 8
HAL 8
gag 7
osteocalcin 7
F8A 7
MHC 7
CTLA4 7
natural killer cell 7
tumor necrosis factor 7
non-functional 7
interleukin-10 7
RIN 7
ABO blood group 7
ABO 7
F5F8D 7
MHC class II 7
ICD 7
GPIb 7
fibronectin 7
TGA 7
CD40 7
polypeptide 7
HLA class I 7
zinc finger 7
megakaryocyte 7
F8C 7
HLA class II 7
androgen receptor 7
lipopolysaccharide 7
PCC 7
protease inhibitor 7
Gen 7
more...
Disease
haemophilia 10958
Haemophilia 6549
HIV 748
von Willebrand disease 656
arthropathy 636
hemophilia B 490
AIDS 426
immunodeficiency 378
hepatitis C 338
cancer 257
synovitis 189
hepatitis 175
coagulopathy 168
hepatitis B 159
thrombocytopenia 145
liver disease 124
Acquired hemophilia 111
arthritis 100
diabetes 92
cirrhosis 91
chronic hepatitis 85
rheumatoid arthritis 82
anemia 80
infectious diseases 74
hypertension 72
cystic fibrosis 69
leukemia 69
osteoarthritis 68
thalassemia 67
disseminated intravascular coagulation 66
systemic lupus erythematosus 63
lymphadenopathy 62
Glanzmann's thrombasthenia 57
hepatitis A 57
virus infection 56
abortion 56
sickle cell disease 55
cardiovascular disease 55
osteoporosis 49
tumor 49
depression 46
hepatocellular carcinoma 45
chronic liver disease 43
obesity 43
ARC 42
sepsis 42
lupus 42
lymphoma 42
genetic disorder 42
stroke 42
autoimmune disease 41
Hemophilic arthropathy 41
chronic pain 39
sepsis 39
lupus 38
chronic disease 38
myocardial infarction 37
arthrodesis 35
Duchenne muscular dystrophy 35
Infection 34
parvovirus 33
cytomegalovirus 32
rare disease 32
viral hepatitis 31
viremia 30
deep vein thrombosis 30
hemorrhagic diathesis 29
coronary artery disease 29
thrombocytopenic purpura 28
PCP 27
septic arthritis 26
malnutrition 26
idiopathic thrombocytopenic purpura 26
Kaposi's sarcoma 26
muscular dystrophy 25
Bernard-Soulier syndrome 23
hemoglobinopathies 22
nephrotic syndrome 22
immune deficiency 22
asthma 20
myocardial ischemia 20
West 19
heart disease 19
pneumonia 19
Down syndrome 19
lymphopenia 19
Creutzfeldt-Jakob disease 19
SCID 18
renal disease 18
Huntington's disease 18
atherosclerosis 18
Best 17
anaphylaxis 17
Hodgkin's disease 17
afibrinogenemia 16
opportunistic infection 16
purpura 16
Poland 16
Epstein 16
multiple sclerosis 15
tuberculosis 15
juvenile rheumatoid arthritis 15
platelet disorder 15
SDS 15
thrombophlebitis 14
hemangioma 14
villonodular synovitis 14
uremia 14
Gilbert 14
Rosenthal 14
vasculitis 14
muscular atrophy 14
plaque 13
hypothyroidism 13
FPP 13
heart failure 13
carcinoma 13
hemolytic anemia 13
pulmonary embolism 13
chronic active hepatitis 13
aplastic anemia 13
liver fibrosis 12
chronic renal failure 12
neuropathy 12
multiple myeloma 12
blood disorder 12
HTLV-I 12
joint effusion 12
liver cancer 12
LCA 11
HCV coinfection 11
cold 11
compartment syndrome 11
dysplasia 11
phenylketonuria 11
HIV disease progression 11
mental retardation 11
renal failure 11
vascular disease 11
mental retardation 11
hepatitis G 11
Glanzmann 10
hemochromatosis 10
Parkinson's disease 10
rash 10
Thrombus 10
hypercholesterolemia 10
SEM 10
intravenous drug abuse 10
acute myocardial infarction 10
prostate cancer 10
liver cancer 10
clotting factor deficiency 10
non-Hodgkin's lymphoma 10
Mycobacterium 10
fragile X syndrome 9
Gaucher disease 9
syphilis 9
osteomyelitis 9
epilepsy 9
more...
Symptom
pain 348
anesthesia 56
arthralgia 33
overweight 23
headache 18
discomfort 16
seizures 16
discomfort 16
weakness 15
abdominal pain 14
splenomegaly 12
analgesia 10
acute pain 10
ENT 9
stigma 9
back pain 9
vomiting 9
flushing 9
knee pain 7
diarrhea 7
respiratory distress 7
hip pain 7
nausea 7
distraction 6
hepatomegaly 6
fatigue 6
angina 6
hepatosplenomegaly 6
functional recovery 6
DNA marker 5
dyspnea 5
ovulatory bleeding 4
paresthesia 4
torticollis 4
hemoptysis 4
shoulder pain 4
neck pain 3
tense 3
acute abdomen 3
exhaustion 3
intestinal bleeding 3
Ill 3
pallor 3
menometrorrhagia 3
elbow pain 3
sore throat 3
low back pain 2
consciousness disturbance 2
nausea and vomiting 2
chest pain 2
agitation 2
apathy 2
chorea 2
groin pain 2
enuresis 2
dizziness 2
nocturnal polyuria 2
hopelessness 2
body pain 2
fever of unknown origin 2
paresis 2
musculoskeletal impairment 2
bone pain 2
ankle pain 2
hemiplegia 2
colic 2
hypothermia 2
meningism 2
erythema 2
leg pain 2
lethargy 2
abnormal bruising 1
swollen joints 1
epigastric pain 1
renal colic 1
Mechanical pain 1
painful swallowing 1
Cutaneous anergy 1
polydipsia 1
acute low back pain 1
paraparesis 1
monoplegia 1
Respiratory symptoms 1
spasticity 1
neuralgia 1
No adverse effect 1
thinning 1
physical appearance 1
Joint hypermobility 1
lassitude 1
cough 1
persistent cough 1
numbness 1
rigors 1
sleepiness 1
spasm 1
dysarthria 1
thigh pain 1
adenitis 1
otalgia 1
hypotonia 1
myoclonus 1
left upper quadrant pain 1
chronic back pain 1
starvation 1
bedwetting 1
right upper quadrant pain 1
stridor 1
Quadriceps weakness 1
flank pain 1
tingling 1
anorexia 1
collapse 1
tinnitus 1
dyschezia 1
pelvic pain 1
PAIN 1
prostration 1
tremor 1
myalgia 1
HSA 1
asthenia 1
regurgitation 1
hoarseness 1
joint stiffness 1
chills 1
ataxia 1
acute abdominal pain 1
forgetfulness 1
decreased appetite 1
not coping 1
Multimorbidity 1
Roth spots 1
vertigo 1
abdominal discomfort 1
Drug
NovoSeven 128
DDAVP 117
AHF 115
DDAVP 115
PTC 93
Bayer 26
Rituximab 22
Kogenate FS 18
PFA 18
Dermatol 16
IL-2 16
Cardiovasc 13
ENT 13
lysine 13
Antihemophilic factor 11
Desmopressin acetate 10
AZT 8
AZT 8
Mononine 7
Leaf 7
Albumin 6
CTX 6
IFN-gamma 6
Alliance 6
Asn 6
Gel 5
Campath 4
Dakar 4
THA 4
CTX 4
EE2 4
CTX 4
Prednisolone 4
Prednisone 4
MAP 4
uPA 4
Campath 4
Monit 3
Orphan 3
Vitamin B12 3
Award 3
Dial 3
Aprotinin 3
Kaolin 3
EPI 2
Ethanol 2
Nonacog alfa 2
ddI 2
CaCl2 2
CaCl2 2
Mutagen 2
CaCl2 2
Gelfoam 2
ROC 2
ACT 2
Clopidogrel 2
G418 2
Heme 2
Raltegravir 2
Nephron 2
Immune globulin 2
Alanine 2
CTA 2
FeCl3 1
DNase I 1
G-CSF 1
Voltaren 1
PCP 1
Xanthium 1
Vitamin K 1
Diclofenac sodium 1
Botox 1
Portal 1
AGG 1
Tocilizumab 1
NAG 1
ADR 1
Pentamidine isethionate 1
IL-11 1
Mezlocillin 1
TAT 1
AMC 1
Trimethoprim-sulfamethoxazole 1
MDS 1
Axitinib 1
Posture 1
Acyclovir 1
CTC 1
Check 1
ascorbate 1
PDL 1
ALA 1
Domin 1
Adalimumab 1
Activase 1
Coumadin 1
Citric acid 1
p75 1
Orlistat 1
Fraction 1
Meth 1
Fragment 1
Asthma 1
lactose 1
GRF 1
SPP 1
PFT 1
Aztec 1
Epsilon-Aminocaproic acid 1
Gamma globulin 1
Antithrombin III 1
IFN-beta 1
CTC 1
Ibandronate 1
L-tyrosine 1
Enzyme
thrombin 349
thromboplastin 325
APC 56
alanine aminotransferase 48
tissue plasminogen activator 27
plasmin 18
coagulation factor VIIa 16
aspartate aminotransferase 14
alkaline phosphatase 13
reverse transcriptase 12
endonuclease 12
AST 10
thrombin-activatable fibrinolysis inhibitor 9
urokinase-type plasminogen activator 8
ERK 8
luciferase 8
beta-galactosidase 7
peroxidase 6
matriptase 5
trypsin 5
ceruloplasmin 5
Hageman factor 4
focal adhesion kinase 4
MAP 4
renin 4
glucose-6-phosphate dehydrogenase 3
proteasome 3
ECH 3
STR 3
pepsin 3
adenosine deaminase 2
phosphoglycerate kinase 2
asparaginase 2
MCS 2
furin 2
prostate-specific antigen 2
protein kinase 2
lipoprotein lipase 2
protein kinase C 2
collagenase 2
BAT 2
adenosine deaminase 2
thyroid peroxidase 2
MIP 2
adenylate kinase 2
chymotrypsin 2
hypoxanthine-guanine phosphoribosyltransferase 2
ACS 2
tyrosine hydroxylase 2
CPS 2
gamma-glutamyl transpeptidase 2
endoglycosidase H 2
DNA polymerase 2
caspase-3 2
alpha-galactosidase 2
lysyl endopeptidase 1
acid phosphatase 1
TAT 1
proteinase K 1
carboxypeptidase B 1
creatine kinase 1
PAM 1
PCP 1
beta-glucuronidase 1
GTI 1
phosphoglucomutase 1
GP-I 1
granzyme B 1
MMP-3 1
firefly luciferase 1
CGT 1
phospholipase C 1
SPC 1
cathepsin G 1
CEP 1
tyrosinase 1
ACE 1
6-phosphogluconate dehydrogenase 1
FPS 1
mitogen-activated protein kinase 1
TGT 1
factor C 1
meprin 1
lecithin:cholesterol acyltransferase 1
PNGase F 1
arginase 1
apyrase 1
methylenetetrahydrofolate reductase 1
phosphoenolpyruvate carboxykinase 1
sulfatase 1
coagulation factor IXa 1
phosphoenolpyruvate carboxykinase 1
acetylcholinesterase 1
RNase 1
catalase 1
aspartylglucosaminidase 1
HIV-1 protease 1
adenine phosphoribosyltransferase 1
6-phosphogluconate dehydrogenase 1
coagulation factor XIa 1
NOS 1
ornithine transcarbamylase 1
cholinesterase 1
kallikrein 1
methylenetetrahydrofolate reductase 1
ACAT 1
aldolase 1
elastase 1
GMT 1
phosphoenolpyruvate carboxykinase 1
lactate dehydrogenase 1
PPH 1
CEP 1
urease 1
aromatic L-amino acid decarboxylase 1
UDP-glucuronosyltransferase 1
neuraminidase 1
transcriptase 1
glutathione S-transferase 1
calcineurin 1
aldehyde dehydrogenase 1
heparinase 1
DNase 1
FAST 1
RNA polymerase 1
cholesterol acyltransferase 1
phenylalanine hydroxylase 1
Compound
Clin 502
Dec 441
DNA 416
His 58
calcium 58
Desmopressin 55
iron 48
arginine 47
Thrombin 45
PEG 27
water 26
Optimal 23
leucine 21
alanine 21
acetate 21
ADP 19
Factor X 19
phosphate 18
serine 18
Asp 16
SDS 16
ADP 16
neopterin 16
ADP 16
sodium 15
Fibrin 15
lysine 15
Tranexamic acid 15
6-12 14
oxygen 14
Heme 14
vitamin D 14
tyrosine 13
ITP 13
DIC 13
sulfate 12
AZT 12
ACS 11
urea 11
PEG 11
phosphorus 11
TNF 11
Ile 10
hyaluronic acid 10
Fibrinogen 10
Gly 10
Cardiol 10
DEAE 9
glucose 9
methionine 8
glutamine 8
threonine 8
cysteine 8
Off 8
Heparin 7
hydrogen 7
creatinine 6
proline 6
CTX 6
aspartic acid 6
nitric oxide 6
aluminum 6
Neo 6
COS 6
Vitamin D 6
Phe 5
Abbott 5
Pac 5
asparagine 5
BPL 5
acrylamide 5
galactose 5
tryptophan 5
ethanol 5
Argentine 5
ASA 5
isopropanol 5
aldosterone 4
glutamate 4
A 71 4
Prednisolone 4
Rifampicin 4
ATP 4
tryptophan 4
tryptophan 4
Danazol 4
TTP 4
valine 4
glutamic acid 4
aspartic acid 4
Vasopressin 4
PPD 4
PPD 4
barium 4
aspartic acid 4
A 3 4
MAP 4
copper 4
tryptophan 4
zinc 4
iodine 4
Prednisone 4
APAP 4
formaldehyde 4
aspartic acid 4
TEG 4
NH2 4
Hemoglobin 4
Dial 3
AHA 3
A 42 3
CCC 3
Cyclosporine 3
HCP 3
Plasmin 3
cGMP 3
PMA 3
isoleucine 3
silver 3
EDTA 3
hydroxide 3
HEP 3
HCP 3
ATA 3
Ribavirin 3
CO2 3
DMD 3
CIT 3
salt 3
isoleucine 3
Panam 3
PAM 2
Retard 2
IPA 2
IPA 2
Collagen 2
BaCl2 2
PRN 2
PAM 2
HAQ 2
Ritonavir 2
LPC 2
Isoproterenol 2
Hearts 2
GM1 2
BCG 2
AMP 2
homocysteine 2
ammonia 2
TMP 2
ALP 2
Mato 2
C 5 2
Alanine 2
ACS 2
PMA 2
fluorine 2
ornithine 2
Glycyrrhizin 2
T 1 2
more...