Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0684249 (lung carcinoma)
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Human Gene/Protein
small nuclear ribonucleoprotein polypeptide B 10.4
zinc finger protein 800 10.4
ASB-8 10.4
c-bas/has 10.4
X102 10.4
RAB5A protein 10.4
topoisomerase III beta 10.4
ATXN7L2 10.4
PRAME family member 10.4
MAP4K3 protein 10.4
GNAI2B 10.4
OTX3 10.4
Family with sequence similarity 129, member A 10.4
bromodomain containing 2 10.4
H2BFS 10.4
C1orf142 10.4
pre T-cell antigen receptor alpha 10.4
HLC-2 9.9
carbonic dehydratase 9.4
Desmocollin-3 9.4
tRNA isopentenyltransferase 1 9.4
ALKBH1 protein 9.4
heterogeneous nuclear ribonucleoprotein U-like 2 9.4
EDIL3 protein 9.4
ZNF560 9.4
Olfactomedin 3 9.4
HIST2H2BF 9.4
A type IV collagen 9.4
Vasopressin-neurophysin 9.4
INFA 9.4
Delta-like 1 protein 9.4
WDYHV1 9.4
DIL-1 9.4
HIST1H2BO 9.4
deleted in azoospermia 1 9.4
MS4A8 9.4
rho GTPase activating protein 9.4
SNRPC 9.4
GTP-binding protein SAR1 9.4
voltage-gated calcium channel alpha 1 subunit 9.4
ZNF165 protein 9.4
attractin-like 1 9.4
NADH dehydrogenase (ubiquinone) Fe-S protein 2 9.4
C8orf48 9.4
RUNDC3B 8.8
TMEM92 8.8
FAM179A 8.8
HIST1H2BL 8.8
OR4C6 8.8
uveal autoantigen with coiled coil domains and ankyrin repeats 8.8
makorin ring finger protein 1 8.8
ODZ2 8.8
C9orf9 8.8
Neuroendocrine-specific protein 8.8
ZNF35 8.8
aldehyde dehydrogenase 7 8.8
OR2B6 8.8
FLJ40296 8.8
COTL1 8.8
DEFB127 8.8
LLC1 8.7
LOC123688 8.6
L-myc protein 8.5
rlf 8.5
PHP14 8.4
Transmembrane protein 106A 8.4
ZNF645 8.4
MFSD2 8.4
ZNF589 8.4
chemokine BRAK 8.4
KAT protein 8.4
CMKOR1 8.4
basic helix-loop-helix domain-containing 8.4
Ras-related protein Rab-7b 8.4
C3orf1 8.4
TSPAN14 8.4
HGFL 8.4
TUBB2 8.4
LCRMP 8.4
Kangai 1 8.1
more...
Disease
Scar emphysema 10.4
Metastases to soft tissue 10.4
Total airway obstruction 10.4
Null cell acute lymphoblastic leukemia 10.4
lung carcinoma 10.4
Intestinal carcinoma 10.4
Malignant esophageal stricture 10.4
nervous system carcinoma 10.4
Pulmonary Pathology 9.6
Familial Atypical Multiple Mole-Melanoma 9.4
Thymic epithelial neoplasm 9.4
squamous cell carcinoma of the larynx, stage II 9.4
Pharyngeal Carcinoma 9.4
Non-caseating epithelioid cell granulomas 8.8
Malignant pericarditis 8.8
Paraneoplastic optic neuropathy 8.8
Giant cell carcinoma 8.7
Pleomorphic carcinoma 8.7
carcinoma of the brain 8.6
Tumorlet 8.4
SCA18 8.4
cancer associated retinopathy 8.2
large cell carcinomas 8.1
stage II NSCLC 8.1
stage III NSCLC 8.1
Basaloid carcinoma 8.1
Primary achalasia 8.1
Myofibrosarcoma 8.1
recurrent NSCLC 8.0
Paraneoplastic encephalomyelitis 7.9
lung cancer 7.9
stage IV NSCLC 7.8
Combined small cell carcinoma 7.8
Endogenous lipoid pneumonia 7.8
Acrokeratosis 7.8
pre-T LBL 7.8
Malignant pyoderma 7.8
recurrent SCLC 7.7
Lambert-Eaton myasthenic syndrome 7.7
stage IIIA NSCLC 7.7
extensive stage SCLC 7.6
Regenerative anemia 7.6
Fetal adenocarcinoma 7.6
Adrenal carcinoma 7.6
stage IIIB NSCLC 7.5
Squamous dysplasia 7.5
limited-stage small cell lung cancer 7.4
bronchioloalveolar carcinoma 7.4
Intra-abdominal metastases 7.4
Erythema gyratum repens 7.4
Acute esophagitis 7.4
Rabbitpox 7.4
stage I NSCLC 7.4
Simple pneumoconiosis 7.2
Typical carcinoid 7.2
squamous cell lung cancer 7.2
lung neoplasm 7.2
Large cell neuroendocrine carcinoma 7.1
adenocarcinoma of the lung 7.1
pulmonary carcinoid tumor 7.0
bronchial neoplasm 7.0
Masquerade syndromes 6.9
Empyema necessitans 6.9
small cell lung cancer 6.9
Squamous Cell Cancer 6.8
Secondary adrenal insufficiency 6.8
Pleural metastases 6.8
Endobronchial metastases 6.8
Radiation esophagitis 6.8
Mesothelioma 6.8
Small cell carcinoma 6.8
ovarian sarcoma 6.8
non-small cell lung cancer 6.7
lung sarcoma 6.7
Sarcoma 37 6.7
ADH3*2 6.7
SCCH 6.7
Anaplastic Lymphoma 6.7
Opsoclonus-myoclonus syndrome 6.7
Adenosquamous carcinoma 6.7
more...
Symptom
photopsia 4.9
Referred pain 4.7
General symptoms 4.5
brittle nails 4.4
staggering gait 4.3
penile lesion 4.2
Sister Mary Joseph's nodule 4.2
hemoptysis 4.1
cachexia 4.0
Spasmodic Torticollis 4.0
Musculoskeletal symptoms 3.7
nerve pain 3.6
productive cough 3.4
asthenia 3.4
nausea and vomiting 3.1
menometrorrhagia 3.1
loin pain 3.0
arm pain 3.0
cough 2.9
blushing 2.9
jaw pain 2.9
Neurologic symptoms 2.9
arm weakness 2.9
dyspnea 2.8
myoclonus 2.6
shortness of breath 2.6
clubbing 2.6
orthopnea 2.5
ACHE 2.5
cerebellar ataxia 2.5
nausea 2.5
body pain 2.3
Postoperative nausea and vomiting 2.3
hoarseness 2.3
consciousness disturbance 2.3
anorexia 2.3
personality change 2.3
chronic cough 2.2
Gastrointestinal symptoms 2.2
pleuritic chest pain 2.2
Burning 2.1
persistent cough 2.1
chest pain 2.1
vomiting 2.0
Physical findings 2.0
testicular pain 1.9
paresthesia 1.9
loss of taste 1.8
epigastric pain 1.8
mastalgia 1.8
acute abdomen 1.8
Scratch 1.8
night sweats 1.7
rigors 1.7
blurred vision 1.7
dysarthria 1.7
tingling 1.7
exertional dyspnea 1.7
splenomegaly 1.6
cancer pain 1.6
polydipsia 1.6
Spots 1.6
weakness 1.5
shoulder pain 1.5
acute abdominal pain 1.4
syncopal episodes 1.4
myalgia 1.4
dry skin 1.4
ataxia 1.4
numbness 1.4
chorea 1.3
emaciation 1.3
hyperesthesia 1.3
POA 1.3
ataxic gait 1.3
bloating 1.3
adenitis 1.2
constipation 1.2
stridor 1.2
facial pain 1.2
more...
Drug
Belagenpumatucel-L 8.1
Carzelesin 7.9
1-Aminoethyl 7.8
Ilmofosine 7.7
Bavituximab 7.2
7-Hydroxystaurosporine 7.2
Pemetrexed 7.2
Adozelesin 7.2
Zedoary 7.1
Paclitaxel poliglumex 6.9
Alimta 6.9
Pemetrexed disodium 6.8
Vinorelbine 6.8
Trimegestone 6.8
Gefitinib 6.8
Erlotinib 6.6
Tarceva 6.4
Lubeluzole 6.4
Epoetin beta 6.4
Navelbine 6.3
Toad venom 6.3
Prinomastat 6.2
Atractylodes rhizome 6.2
Etoposide phosphate 6.1
Vindesine 6.1
Dilaudid 6.1
Leucin 6.1
Vindesine 6.1
Edatrexate 6.0
Troxacitabine 6.0
Plaunotol 6.0
Avasimibe 5.8
Sparsomycin 5.7
Gallium nitrate 5.7
Aclarubicin 5.6
Docetaxel 5.5
Irofulven 5.4
Butaprost 5.4
Gemzar 5.4
Teniposide 5.4
Imagent 5.4
Meth 5.3
Velban 5.2
Vesnarinone 5.1
Arlacel 5.1
Panitumumab 5.0
Flavopiridol 5.0
Bexarotene 4.9
Sandostatin LAR 4.9
Compound 19 4.9
Wellferon 4.9
Etoposide 4.9
Podophyllotoxin 4.9
Paraplatin 4.8
Taxotere 4.8
Human Serum Albumin 4.7
ZnI2 4.6
Epidoxorubicin 4.6
CPT-11 4.6
Parecoxib 4.6
Dexrazoxane 4.6
Irinotecan 4.5
Ontak 4.5
Ontak 4.5
Adriamycin 4.4
Photofrin 4.3
Tiopronin 4.3
Epoetin alfa 4.3
Levamisol 4.3
VCR 4.3
Talc 4.2
Bestatin 4.2
Marimastat 4.2
Cetuximab 4.2
ADR 4.1
Maxon 4.1
Taxol 4.1
Lipitor 4.0
Darbepoetin alfa 4.0
Podophyllum 4.0
more...
Enzyme
prostaglandin 13-reductase 8.4
EC 3.4.19.1 6.0
L-lysine alpha-oxidase 6.0
GalNAc4S-6ST 5.7
spermidine/spermine N1-acetyltransferase 5.6
DNA 3'-phosphatase 5.6
FGAM synthetase 5.4
heparitinase I 5.0
tubulin carboxypeptidase 5.0
deoxycytidine deaminase 5.0
caspase-5 4.9
PGE2 isomerase 4.7
dCMP deaminase 4.5
polyamine oxidase 4.3
STK11 4.3
10-formyltetrahydrofolate dehydrogenase 4.3
serralysin 4.2
macrophage elastase 4.2
pyridoxal kinase 4.2
dihydrodiol dehydrogenase 4.2
caspase-5 4.2
methylthioadenosine phosphorylase 4.1
enolase 4.1
endoglycoceramidase 4.1
CMP kinase 4.1
methioninase 4.0
orotate phosphoribosyltransferase 4.0
deoxycytidine kinase 3.9
chondroitin ABC lyase 3.9
dihydropyrimidine dehydrogenase 3.9
TSR 3.9
proline oxidase 3.9
EC 2.6.1.16 3.9
polypeptide N-acetylgalactosaminyltransferase 3.9
thymidylate synthase 3.9
cancer procoagulant 3.8
CDP-diacylglycerol synthase 3.8
MTD 3.7
topoisomerase 3.7
topoisomerase 3.7
ketohexokinase 3.7
ERK 3.7
GM3 synthase 3.6
DAP II 3.6
GalNAc-T 3.6
phosphofructokinase 1 3.5
LDT 3.5
glucosylceramide synthase 3.5
ornithine aminotransferase 3.5
amidophosphoribosyltransferase 3.5
matrix metalloproteinase 2 3.5
LTC4 synthase 3.4
dihydropyrimidine dehydrogenase 3.4
glycyl-tRNA synthetase 3.4
glycoprotease 3.4
prostacyclin synthase 3.4
cathepsin C 3.4
AiiA 3.4
riboflavin kinase 3.4
stromelysin-3 3.3
aromatic L-amino acid decarboxylase 3.3
urokinase-type plasminogen activator 3.3
SPC 3.2
cytosine deaminase 3.2
CEP 3.2
IOR 3.2
HDR 3.1
SST 3.1
P-glycoprotein 3.1
ribonucleotide reductase 3.1
caspase-9 3.1
cytidine deaminase 3.0
spermidine synthase 3.0
caspase-8 3.0
cathepsin B 3.0
pyroglutamate aminopeptidase 3.0
ribonucleotide reductase 3.0
Omi/HtrA2 3.0
PARP 3.0
folylpolyglutamate synthetase 2.9
more...
Compound
Swertianolin 10.4
4-Peroxycyclophosphamide 10.4
cis-CCCNU 10.4
1-oxo-1H-isothiochromene-3-carboxylic acid 10.4
Isogentisin 10.4
1H-naphtho[2,3-d]imidazole-4,9-dione 9.4
2-butanone thiosemicarbazone 9.4
2,5-dimethyl-3-furoic acid 9.4
C19H18O11 9.4
1,4-dibromo-2-butanol 9.4
Dihydroactinidiolide 9.4
K-DR 9.2
C6H13NO2 8.8
Capillin 8.8
Isophosphoramide mustard 8.8
2,4,5-trichloropyrimidine 8.8
C20H24O7 8.8
Lavendamycin 8.8
Tallysomycin A 8.8
Gentisin 8.8
Stictic acid 8.8
CI 301 8.8
9-beta-D-arabinofuranosyl-9H-purine-6-thiol, 8.8
N-hydroxy-5-phenylpentanamide 8.6
CI-921 8.4
H-69 8.3
2-(difluoromethyl)ornithine 8.2
11H-indeno[1,2-b]quinoline 8.1
11H-indeno[1,2-b]quinoline 8.1
H-82 8.1
GANU 8.0
C20H26O6 7.8
Ouabagenin 7.8
Cymarin 7.8
Vasicinone 7.8
4-methoxybenzohydrazide 7.8
GANU 7.7
Tetrahydrocortisol 7.7
Cotylenin A 7.6
2-isopropyl-1,3-dioxolane 7.6
Pyrazine diazohydroxide 7.6
AD 32 7.4
RPCNU 7.4
Illudin S 7.3
Acronycine 7.2
4-aminocyclohexanecarboxylic acid 7.2
4-aminocyclohexanecarboxylic acid 7.2
Clomesone 7.1
hexanediamide 7.1
Prospidin 6.9
Triptonide 6.9
6-phenylphenanthridine 6.9
Gilvocarcin V 6.9
benzo[a]phenazine 6.9
Pyrazine diazohydroxide 6.9
Loganic acid 6.8
Staphyloxanthin 6.8
alpha-Hederin 6.7
Pectolinarigenin 6.7
RFCNU 6.7
Mitozolomide 6.7
Harmol 6.5
2-oxopropanamide 6.5
2,6-piperazinedione 6.5
Gilvocarcin V 6.5
2-amino-5-methylphenol 6.5
Nitrosamine 6.5
CCNU 6.3
Sialyl Lewis a 6.3
Harringtonine 6.3
Harringtonine 6.3
Ferrioxamine 6.3
Chartreusin 6.3
Harringtonine 6.3
BCME 6.3
7-methoxy-2H-chromen-2-one 6.2
Hederagenin 6.2
Deoxydoxorubicin 6.2
4-Ipomeanol 6.2
Pyran 6.2
more...