Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0684249 (
lung carcinoma
)
23,830
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
1565
p53
685
epidermal growth factor receptor
636
Mol
622
tyrosine kinase
588
EGFR
437
colon carcinoma
276
vascular endothelial growth factor
272
caspase-3
213
cytokine
203
nodal
187
NMR
184
Bcl-2
183
TNM
173
ALK
168
p21
156
CD8
138
KRAS
134
anaplastic lymphoma kinase
132
VEGF
130
AKT
125
carcinoembryonic antigen
122
tumor necrosis factor
119
FDG
117
interferon
115
E-cadherin
114
ATP
110
MRI
110
mTOR
110
glycoprotein
109
PD-L1
108
cage
107
neuron-specific enolase
107
PI3K
106
collagen
100
ERK
97
matrix metalloproteinase
96
She
95
vimentin
95
IFN
93
bombesin
93
fibronectin
92
epidermal growth factor
91
CD4
91
ras
88
Ki-67
88
MET
87
p38
85
P-glycoprotein
85
TNF
84
thymus
84
MAPK
83
cyclin D1
81
HER2
81
ERK1
81
K-ras
80
lymphoid
79
Calu
78
cytokeratin
76
proteasome
76
PD-1
74
gastrin-releasing peptide
73
PARP
73
Epidermal growth factor receptor
72
BRAF
72
vasopressin
72
MMP-9
72
c-myc
72
IL-6
72
GSH
72
polypeptide
69
IFN-gamma
68
MMP-2
68
MEK
66
urokinase-type plasminogen activator
65
IL-2
64
receptor tyrosine kinase
64
mucin
64
histone
64
fused
63
more...
Disease
lung carcinoma
23830
lung cancer
12580
cancer
7291
tumor
7156
carcinoma
2771
adenocarcinoma
2150
non-small cell lung cancer
1813
metastases
1736
tumor growth
1106
squamous cell carcinoma
998
melanoma
959
small cell lung cancer
589
primary tumor
516
leukemia
489
tumor progression
458
breast cancer
399
carcinogenesis
393
mesothelioma
354
tumorigenesis
331
hepatocellular carcinoma
302
lymphoma
253
lung metastases
229
sarcoma
228
MCF
227
brain metastases
227
neutropenia
212
pneumonia
179
carcinoid
178
renal cell carcinoma
176
thrombocytopenia
175
adenocarcinoma of the lung
154
fibrosarcoma
154
neuroblastoma
151
epithelial ovarian cancer
143
Thoracic
141
bronchogenic carcinoma
137
neuroendocrine carcinoma
125
tumor angiogenesis
124
anemia
118
solid tumor
118
malignant mesothelioma
116
colon cancer
115
prostate cancer
114
glioblastoma
111
myelosuppression
104
leukopenia
104
Lambert-Eaton myasthenic syndrome
99
glioma
95
tuberculosis
95
multiple myeloma
93
bronchioloalveolar carcinoma
93
retinoblastoma
87
chronic obstructive pulmonary disease
87
colorectal cancer
83
stage III NSCLC
77
large cell carcinomas
77
lung disease
75
osteosarcoma
74
lymphadenopathy
73
GSH
72
Hodgkin's disease
72
ovarian cancer
71
paraneoplastic syndrome
70
sarcoma 180
70
bone metastases
70
liver metastases
69
dysplasia
69
Small cell carcinoma
65
aggressiveness
63
depression
62
encephalitis
60
tumor vasculature
58
esophagitis
58
Adenocarcinoma
56
bladder cancer
56
neuroendocrine tumor
55
malignant pleural effusion
53
residual disease
53
neuropathy
52
pancreatic cancer
51
more...
Symptom
pain
151
dyspnea
144
cough
136
vomiting
98
nausea
96
diarrhea
89
fatigue
86
weakness
83
hemoptysis
77
cachexia
70
nausea and vomiting
62
chest pain
56
anorexia
50
headache
35
ataxia
31
abdominal pain
30
anesthesia
30
collapse
26
seizures
25
shortness of breath
24
splenomegaly
23
asthenia
21
myoclonus
20
back pain
18
constipation
18
discomfort
16
cerebellar ataxia
15
respiratory distress
15
paresthesia
14
Ill
13
myalgia
13
discomfort
12
hoarseness
11
erythema
11
analgesia
11
starvation
11
dizziness
10
numbness
10
exhaustion
10
sleepiness
9
dysarthria
9
productive cough
9
epigastric pain
9
hepatomegaly
8
exertional dyspnea
8
acute abdomen
8
vertigo
7
chronic cough
7
paresis
7
cancer pain
7
arthralgia
7
shoulder pain
6
chills
6
lethargy
6
angina
6
low back pain
6
blurred vision
5
hyperoxia
5
polyuria
5
polydipsia
5
facial pain
4
clubbing
4
memory loss
4
stridor
4
acute abdominal pain
4
chorea
4
insomnia
4
overweight
3
sore throat
3
wheezing
3
pallor
3
arm pain
3
night sweats
3
consciousness disturbance
3
agitation
3
photopsia
3
syncope
3
flank pain
3
neck pain
3
tingling
3
more...
Drug
Cardiovasc
151
Gefitinib
98
Adriamycin
74
IFN-gamma
65
CSF
64
IL-2
64
ROS
60
Docetaxel
59
CTX
58
Erlotinib
55
lysine
49
Pemetrexed
44
Meth
41
Dermatol
40
Taxol
40
Vinorelbine
36
MRC
35
CPT-11
34
ADR
27
Etoposide
25
CTX
21
CTX
21
vitamin E
21
Bevacizumab
20
G-CSF
19
MAP
18
Glutathione
18
TTC
18
ADM
16
VCR
15
uPA
14
ROC
14
ascorbate
14
Tarceva
14
Photofrin
14
Irinotecan
14
Paraffin
14
Taxotere
13
Cetuximab
13
NADH
12
caffeine
12
Gel
11
Mutagen
11
Monit
11
Bortezomib
11
Navelbine
11
CCL
11
CAM
10
ABC
10
IFN-beta
10
DNase I
10
VCR
9
GEO
9
PTH
9
Herceptin
8
Imatinib
8
G418
8
NVP
8
TAT
7
Alimta
7
Leaf
7
Indomethacin
7
Spectrum
6
Arsenic trioxide
6
Vindesine
6
HCG
6
DM1
6
Vindesine
6
Albumin
6
Asthma
6
Retinoic acid
6
Vitamin A
6
Gemzar
6
CDP
6
Tocopherol
6
ENT
6
Silica
5
Pronase
5
Fluorescein
5
Gleevec
5
more...
Enzyme
ERK
913
mitogen-activated protein kinase
312
caspase-3
180
protein kinase
128
luciferase
117
topoisomerase
97
focal adhesion kinase
95
topoisomerase
89
P-glycoprotein
85
MEK
83
protein kinase C
82
PARP
79
proteasome
78
urokinase-type plasminogen activator
78
lactate dehydrogenase
58
reverse transcriptase
53
enolase
47
caspase-9
47
catalase
45
peroxidase
43
alkaline phosphatase
42
caspase-8
41
cdc2
41
thymidylate synthase
39
phosphatidylinositol 3-kinase
38
superoxide dismutase
37
collagenase
36
ACS
35
glutathione S-transferase
33
trypsin
33
thrombin
32
ATPase
30
RNase
29
thymidine kinase
26
NQO1
26
neuraminidase
25
ornithine decarboxylase
25
cathepsin B
25
phosphoinositide 3-kinase
24
RNA polymerase
24
RNase
24
glutathione peroxidase
23
plasmin
23
AMP-activated protein kinase
23
creatine kinase
22
beta-galactosidase
21
dihydrofolate reductase
21
phospholipase C
21
AMPK
20
lysozyme
20
APC
20
matrix metalloproteinase 2
19
calcineurin
19
ribonucleotide reductase
19
SPC
18
MDR
17
ribonucleotide reductase
17
alanine aminotransferase
16
MMP
16
transcriptase
16
DNA polymerase
15
arginase
14
MDP
14
MAP
14
AMPK
13
protein phosphatase 2A
12
neutrophil elastase
12
MMP-3
12
acetylcholinesterase
12
granzyme B
12
NADPH oxidase
11
gamma-glutamyl transpeptidase
11
NOS
11
glutathione reductase
11
GSK
11
acid phosphatase
11
NADPH oxidase
11
lipoxygenase
10
DNA methyltransferase
10
adenylate cyclase
10
more...
Compound
Clin
2876
Dec
1834
DNA
1504
oxygen
321
water
249
MTT
243
calcium
207
tyrosine
195
TNM
173
sodium
168
glucose
143
methionine
138
DDP
137
MDA
111
ATP
110
acetate
109
Adriamycin
106
VP-16
99
phosphate
95
sulfate
90
GSH
85
GSH
85
arginine
85
TNF
84
bromide
81
hydrogen
80
lysine
75
PEG
75
leucine
74
cysteine
70
His
70
ethanol
69
serine
68
MEK
68
galactose
68
nitrogen
68
nitric oxide
65
iodine
64
ADR
63
CTX
58
threonine
57
PEG
57
iron
56
CCNU
55
ACTH
53
pyrene
53
Docetaxel
53
Paclitaxel
52
cAMP
52
retinoic acid
52
Gemcitabine
51
Gemcitabine
51
NH2
51
SCC
50
alanine
49
CBDCA
48
methanol
48
CBDCA
48
salt
47
pyrimidine
43
pyrimidine
43
5-FU
42
zinc
42
silver
41
copper
41
SDS
40
acridine
40
potassium
37
MES
36
MES
36
urea
36
BCNU
36
Phe
35
PGE2
35
GM1
35
Asp
34
ACS
34
ACS
34
DBA
33
CPT-11
33
more...