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Query: UMLS:C0684249 (lung carcinoma)
 23,830 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Although it is true that pulmonary perfusion scanning is generally accepted primarily in the differential diagnosis of pulmonary embolism, the introduction of regional ventilation studies with radioactive 133Xe, the use of the computer to provide quantitative data, and the advances being made in cardiovascular nuclear medicine indicate that nuclear medicine procedures will be used more and more in the evaluation of patients with a variety of lung and heart diseases. They have already proved of value in the following circumstances: (1) differential diagnosis of pulmonary embolism; (2) assessment of regional involvement in pulmonary parenchymal disease, including degenerative, neoplastic, and infectious diseases; (3) detection of bullous disease and the determination of the possible effectiveness of surgery; (4) assessment of the response to radiation therapy in patients with carcinoma of the lung; (5) detection of pulmonary venous hypertension in patients with mitral valve or left ventricular disease; (6) detection of cor pulmonale; (7) differential diagnosis of cyanosis in newborn infants.
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PMID:The use of radioisotope techniques for the evaluation of patients with pulmonary disease. 124 35

We retrospectively reviewed 46 patients with superior vena cava syndrome during the period 1986-1992. The common symptoms included congestion of collateral veins of the neck, anterior chest wall, face, eyelids and right arm. Dyspoea and cyanosis occurred less frequently. In all but two patients a histological diagnosis was made by invasive and non-invasive examination without complications. In 82% of all patients a primary lung carcinoma was the cause of the superior vena cava syndrome. For 39 patients radiotherapy was the first treatment of choice. To relieve the distressing symptoms patients received one of two regimens employing hypofractionated radiotherapy. In regimen 3F, 25 patients received three weekly high dose fractions of 8 Gy delivering a total dose of 24 Gy. Regimen 2F, applied to seven patients, consisted of two weekly fractions of 8 Gy, giving a total of 24 Gy. In both regimens a good palliative result was established, however the results of the 3F regimen were superior. Using the 3F regimen a partial response was obtained in 96% of all patients, and 56% achieved a complete response. With the 2F regimen a partial response was achieved in 70% of all patients, and a complete response in only 28%. Minimal side effects were noted. After reviewing our experience, the 3F regimen is recommended for rapid and effective relief of the superior vena cava syndrome.
Lung Cancer 1993 Dec
PMID:Hypofractionated radiation therapy in the treatment of superior vena cava syndrome. 752 Dec 65