Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0679427 (
myeloblastosis
)
982
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Chick-embryo cells contain four isoaccepting species of methionine transfer RNA (I-IV). One species (I) is the initiator, tRNA(f) (Met), and the others (II, III, and IV) are the donors of internal methionyl residues (tRNA(m) (Met)). Over 85% of the tRNA(Met) in purified avian
myeloblastosis
virus consists of one tRNA(m) (Met) species, which resembles host-cell tRNA(Met) IV with respect to chromatographic properties on
RPC
-5, electrophoretic mobility of the terminal methionyl-oligonucleotide, and activity in cell-free protein synthesis in response to synthetic and natural messenger RNAs. Thus, tRNA(Met) IV of avian
myeloblastosis
virus is structurally indistinguishable from the corresponding host-cell species, and, although not involved in initiation of viral protein synthesis, is able to function in peptide-chain elongation.
...
PMID:Methionine transfer ribonucleic acids of avian myeloblastosis virus. 435 68
